US4797422A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical compounds effective against several disorders of the eye in particular the cataract and composition containing them
Assignee: Individual
•
Filing: 1986-07-23
•
Granted: 1989-01-10
•
Expires: 2006-07-23
Abstract
Abstract Some compounds having the general formula of R-C6H4-(CH2)n-OH where we find R is hydrogen, or an alkylic group, possibly mono- or bi-substituted, or a hydroxyl group and n is an entire number varying from 1 to 6. Such compounds display the common property of being effective against several disorders of the eye (presbiopia, amblyopia, cataract etc.) and may be used as active principles in a pharmaceutical formulation of ophthalmic topical preparations.
Inventors
- 👤 Michele Testa
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 03:55
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/045; A61K31/13; A61K31/135
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
72 words
A method for the treatment of cataracts of the eye in humans and animals, which comprises topically administering to the eye of a human or animal in need thereof an anti-cataract effective amount of a compound of the formula R--C.sub.6 H.sub.4 --(CH.sub.2).sub.n --OH wherein R is hydrogen, alkyl of 1 to 6 carbon atoms, amino, monosubstituted amino, disubstituted amino, or hydroxyl, and n is a whole number of from 1 to 6.
Claim 2
Independent Claim
72 words
A method for the treatment of cataracts of the eye in humans and animals, which comprises topically administering to the eye of a human or animal in need thereof an anti-cataract effective amount of a compound of the formula R--C.sub.6 H.sub.4 --(CH.sub.2).sub.n --OH wherein R is hydrogen, alkyl of 1 to 6 carbon atoms, amino, monosubstituted amino, disubstituted amino, or hydroxyl, and n is a whole number of from 1 to 6.
Claim 3
Dependent Claim
12 words
The method according to claim 1, wherein said compound is benzyl alcohol.
Claim 4
Dependent Claim
12 words
The method according to claim 1, wherein said compound is m-hydroxybenzyl alcohol.
Claim 5
Dependent Claim
12 words
The method according to claim 1, wherein said compound is m-hydroxybenzyl aniline.
Claim 6
Dependent Claim
83 words
A pharmaceutical composition for the treatment of cataracts of the eye in humans and animals in the form of eyedrops comprising an aqueous solution comprising an anti-cataract effective amount of a compound of the formula R--C.sub.6 H.sub.4 --(CH.sub.2).sub.n --OH wherein R is hydrogen, alkyl of 1 to 6 carbon atoms, amino, monosubstituted amino, disubstituted amino, or hydroxyl, and n is a whole number of from 1 to 6, the concentration of said compound in said aqueous solution being less than 10 -2 M.
Claim 7
Dependent Claim
83 words
A pharmaceutical composition for the treatment of cataracts of the eye in humans and animals in the form of eyedrops comprising an aqueous solution comprising an anti-cataract effective amount of a compound of the formula R--C.sub.6 H.sub.4 --(CH.sub.2).sub.n --OH wherein R is hydrogen, alkyl of 1 to 6 carbon atoms, amino, monosubstituted amino, disubstituted amino, or hydroxyl, and n is a whole number of from 1 to 6, the concentration of said compound in said aqueous solution being less than 10 -2 M.
Claim 8
Dependent Claim
13 words
The composition according to claim 5, wherein said composition is isotonic with tears.
Claim 9
Dependent Claim
12 words
The composition according to claim 5, wherein said compound is benzyl alcohol.
Claim 10
Dependent Claim
12 words
The composition according to claim 5, wherein said compound is m-hydroxybenzyl alcohol.
Claim 11
Dependent Claim
12 words
The composition according to claim 5, wherein said compound is m-hydroxybenzyl aniline.
Claim 12
Independent Claim
93 words
A method for the treatment of cataracts of the eye in humans and animals, which comprises topically administering to the eye of a human or animal in need thereof an anti-cataract effective amount of eyedrops comprising an aqueous solution of a compound of the formula R--C.sub.6 H.sub.4 --(CH.sub.2).sub.n --OH wherein R is hydrogen, alkyl of 1 to 6 carbon atoms, amino, monosubstituted amino, disubstituted amino, or hydroxyl, and n is a whole number of from 1 to 6, the concentration of said compound in said aqueous solution being less than 10 -2 M.
Claim 13
Independent Claim
93 words
A method for the treatment of cataracts of the eye in humans and animals, which comprises topically administering to the eye of a human or animal in need thereof an anti-cataract effective amount of eyedrops comprising an aqueous solution of a compound of the formula R--C.sub.6 H.sub.4 --(CH.sub.2).sub.n --OH wherein R is hydrogen, alkyl of 1 to 6 carbon atoms, amino, monosubstituted amino, disubstituted amino, or hydroxyl, and n is a whole number of from 1 to 6, the concentration of said compound in said aqueous solution being less than 10 -2 M.
Claim 14
Dependent Claim
13 words
The method according to claim 10, wherein said eyedrops are isotonic with tears.
Claim 15
Dependent Claim
12 words
The method according to claim 10, wherein said compound is benzyl alcohol.
Claim 16
Dependent Claim
12 words
The method according to claim 10, wherein said compound is m-hydroxybenzyl alcohol.
Claim 17
Dependent Claim
12 words
The method according to claim 10, wherein said compound is m-hydroxybenzyl aniline.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1992-01-10 | 1992-07-11 | 1993-01-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-01-10 | 1996-07-11 | 1997-01-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-01-10 | 2000-07-11 | 2001-01-10 | $7700.00 | Window Closed / Lapsed |