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US4790640A Expired / Lapsed US ⏱️ 0.0 years remaining

Laboratory slide

Assignee: Individual
•
Filing: 1985-10-11
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Granted: 1988-12-13
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Expires: 2005-10-11
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Abstract

Abstract An improved laboratory slide and related methods of manufacture and use, wherein the slide is designed for analysis and/or testing of liquid specimens and the like. The improved slide comprises a transparent upper coverslip affixed to a lower slide plate by a thin bonding agent of controlled thickness which may be a substantially monocellular thickness on the order of about 0.001 inch or less. In some forms, the bonding agent is shaped in cooperation with the slide plate and coverslip to define one or more examination chambers into which liquid specimens may be drawn by capillary action for viewing and analysis. In other forms, the bonding agent defines one or more elongated flow channels through which a specimen may be drawn, wherein the flow channels may be of varying height and/or include selected reagents along their lengths to perform selected testing of biological specimens and the like.

Inventors

  • 👤 Frederic L. Nason

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 13:06
CPC Classifications
G; G02; G02B; G02B21/00; G02B21/34; B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5027; B01L3/502707; B01L2200/00; B01L2200/06; B01L2200/0689; B01L2200/12; B01L2300/00; B01L2300/08; B01L2300/0809; B01L2300/0822; B01L2300/0861; B01L2300/087; B01L2300/0887; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0406; Y; Y10; Y10S; Y10S436/00; Y10S436/807; Y10S436/809

Claims Analysis

Total Claims: 47
Claim 1
Independent Claim 129 words
A laboratory slide, comprising: a lower slide plate; a transparent coverslip; and an adhesive bonding agent for securing said coverslip in overlying relation upon said slide plate, said bonding agent being interposed directly between said slide plate and coverslip, said bonding agent being patterned to define at least one chamber with a precision controlled and predetermined spacing dimension between said slide plate and coverslip on the order of about 0.003 inch or less; said bonding agent being patterned to define an elongated and open-ended flow channel, said bonding agent cooperating with said slide plate and coverslip to close the top, bottom, and sides of said flow channel, having a precision controlled and predetermined cross sectional size and shape, and further including at least one reagent within said flow channel.
Claim 2
Dependent Claim 129 words
A laboratory slide, comprising: a lower slide plate; a transparent coverslip; and an adhesive bonding agent for securing said coverslip in overlying relation upon said slide plate, said bonding agent being interposed directly between said slide plate and coverslip, said bonding agent being patterned to define at least one chamber with a precision controlled and predetermined spacing dimension between said slide plate and coverslip on the order of about 0.003 inch or less; said bonding agent being patterned to define an elongated and open-ended flow channel, said bonding agent cooperating with said slide plate and coverslip to close the top, bottom, and sides of said flow channel, having a precision controlled and predetermined cross sectional size and shape, and further including at least one reagent within said flow channel.
Claim 3
Dependent Claim 29 words
The laboratory slide of claim 1 wherein said bonding agent secures said slide plate and said coverslip with a spacing therebetween on the order of 0.001 inch or less.
Claim 4
Dependent Claim 17 words
The laboratory slide of claim 1 wherein said bonding agent comprises a layer of an adhesive material.
Claim 5
Dependent Claim 18 words
The laboratory slide of claim 3 wherein said layer has a thickness of about 0.001 inch or less.
Claim 6
Dependent Claim 14 words
The laboratory slide of claim 1 wherein said bonding agent comprises an ink layer.
Claim 7
Dependent Claim 18 words
The laboratory slide of claim 5 wherein said layer has a thickness of about 0.001 inch or less.
Claim 8
Dependent Claim 34 words
The laboratory slide of claim 1 wherein said bonding agent is patterned to define said at least one chamber with a precision controlled and predetermined varying spacing dimension between said slide plate and coverslip.
Claim 9
Dependent Claim 21 words
The laboratory slide of claim 1 wherein said at least one reagent is carried by a substrate within said flow channel.
Claim 10
Dependent Claim 26 words
The laboratory slide of claim 1 wherein said flow channel has varying spacing between said slide plate and coverslip along the length of said flow channel.
Claim 11
Dependent Claim 24 words
The laboratory side of claim 1 wherein said slide plate and said coverslip are formed from the group of transparent glass and transparent plastic.
Claim 12
Dependent Claim 38 words
The laboratory slide of claim 1 wherein said coverslip has at least one opening therein exposing an underlying portion of said slide plate and cooperating therewith to define a specimen application site in flow communication with said chamber.
Claim 13
Dependent Claim 42 words
The laboratory slide of claim 1 wherein said slide plate is formed from a relatively rigid transparent material, said coverlip is formed from a comparatively thin and transparent plastic material, and said bonding agent removably securing said coverslip upon said slide plate.
Claim 14
Dependent Claim 126 words
A laboratory slide; comprising: a lower slide plate; a transparent coverslip; and an adhesive bonding agent for securing said coverslip in overlying relation upon said slide plate, said bonding agent being interposed directly between said slide plate and coverslip, said bonding agent being patterned to define at least one chamber with a precision controlled and predetermined spacing dimension between said slide plate and coverslip on the order of about 0.003 inch or less; said slide plate being sized to protrude beyond one margin of said coverslip, said bonding agent being patterned to define and to surround at least one upwardly open specimen application site upon the portion of said slide plate protruding beyond said coverslip margin, said application site communicating with said at least one chamber.
Claim 15
Dependent Claim 126 words
A laboratory slide; comprising: a lower slide plate; a transparent coverslip; and an adhesive bonding agent for securing said coverslip in overlying relation upon said slide plate, said bonding agent being interposed directly between said slide plate and coverslip, said bonding agent being patterned to define at least one chamber with a precision controlled and predetermined spacing dimension between said slide plate and coverslip on the order of about 0.003 inch or less; said slide plate being sized to protrude beyond one margin of said coverslip, said bonding agent being patterned to define and to surround at least one upwardly open specimen application site upon the portion of said slide plate protruding beyond said coverslip margin, said application site communicating with said at least one chamber.
Claim 16
Dependent Claim 29 words
The laboratory slide of claim 13 wherein said specimen application site is recessed relative to said chamber and bridges a short distance beyond said one margin of said coverslip.
Claim 17
Dependent Claim 19 words
The laboratory slide of claim 14 wherein said specimen application site comprises an etched region of said slide plate.
Claim 18
Dependent Claim 20 words
The laboratory slide of claim 13 wherein said chamber is vented at a position generally opposite said one side margin.
Claim 19
Dependent Claim 15 words
The laboratory slide of claim 13 including filter means disposed at said specimen application site.
Claim 20
Dependent Claim 52 words
The laboratory slide of claim 13 wherein said slide plate is further sized to protrude beyond a second end of said coverslip, said flow channel extending between said one end and said second end of said coverslip, and further including wick means on said slide plate generally adjacent said coverslip second end.
Claim 21
Dependent Claim 33 words
The laboratory slide of claim 13 wherein said coverslip is formed from transparent plastic and includes a surface discontinuity along said one side margin at a position aligned with said specimen application site.
Claim 22
Dependent Claim 93 words
A laboratory slide; comrising: a lower slide plate; a transparent coverslip; and an adhesive bonding agent for securing said coverslip in overlying relation upon said slide plate, said bonding agent being interposed directly between said slide plate and coverslip, said bonding agent being patterned to define at least one chamber with a precision controlled and predetermined spacing dimension between said slide plate and coverslip on the order of about 0.003 inch or less; said bonding agent being soluble upon contact with a specimen, said bonding agent having at least one reagent carried therein.
Claim 23
Dependent Claim 93 words
A laboratory slide; comrising: a lower slide plate; a transparent coverslip; and an adhesive bonding agent for securing said coverslip in overlying relation upon said slide plate, said bonding agent being interposed directly between said slide plate and coverslip, said bonding agent being patterned to define at least one chamber with a precision controlled and predetermined spacing dimension between said slide plate and coverslip on the order of about 0.003 inch or less; said bonding agent being soluble upon contact with a specimen, said bonding agent having at least one reagent carried therein.
Claim 24
Dependent Claim 58 words
The laboratory slide of claim 20 wherein said bonding agent is patterned to include a first portion defining the sides of a flow channel between said slide plate and coverslip, and a second portion disposed along said flow channel and having a reduced density per unit of slide plate surface area relative to said first bonding agent portion.
Claim 25
Dependent Claim 101 words
A laboratory slide, comprising: a lower slide plate; a transparent coverslip; and bonding means comprising a bonding agent of an adhesive material directly interposed between said slide plate and coverslip and directly securing said slide plate and coverslip generally in overlying relation with respect to each other, said bonding means being patterned to define at least one elongated flow channel between said slide plate and coverslip, said bonding means defining said flow channel with a precision controlled and predetermined spacing dimension between said slide plate and coverslip; said bonding agent having a thickness on the order of 0.001 inch or less.
Claim 26
Dependent Claim 101 words
A laboratory slide, comprising: a lower slide plate; a transparent coverslip; and bonding means comprising a bonding agent of an adhesive material directly interposed between said slide plate and coverslip and directly securing said slide plate and coverslip generally in overlying relation with respect to each other, said bonding means being patterned to define at least one elongated flow channel between said slide plate and coverslip, said bonding means defining said flow channel with a precision controlled and predetermined spacing dimension between said slide plate and coverslip; said bonding agent having a thickness on the order of 0.001 inch or less.
Claim 27
Dependent Claim 94 words
A laboratory slide, comprising: a lower slide plate; a transparent coverslip; and bonding means comprising a bonding agent of an adhesive material directly interposed between said slide plate and coverslip and directly securing said slide plate and coverslip generally in overlying relation with respect to each other, said bonding means being patterned to define at least one elongated flow channel between said slide plate and coverslip, said bonding means defining said flow channel with a precision controlled and predetermined spacing dimension between said slide plate and coverslip; said bonding means comprises an ink layer.
Claim 28
Dependent Claim 94 words
A laboratory slide, comprising: a lower slide plate; a transparent coverslip; and bonding means comprising a bonding agent of an adhesive material directly interposed between said slide plate and coverslip and directly securing said slide plate and coverslip generally in overlying relation with respect to each other, said bonding means being patterned to define at least one elongated flow channel between said slide plate and coverslip, said bonding means defining said flow channel with a precision controlled and predetermined spacing dimension between said slide plate and coverslip; said bonding means comprises an ink layer.
Claim 29
Dependent Claim 21 words
The laboratory slide of claim 23 wherein said ink layer has a thickness on the order of 0.001 inch or less.
Claim 30
Dependent Claim 102 words
A laboratory slide, comprising: a transparent lower slide plate; a bonding agent of precision controlled predetermined thickness disposed directly on said slide plate; and a transparent coverslip secured by direct contact with said bonding agent in overlying relation to and spaced from said slide plate by said bonding agent; said bonding agent being patterned to define an elongated and open-ended flow channel of varying width between said slide plate and coverslip with the flow channel having closed top, bottom and sides; the spacing between said slide plate and coverslip being sufficiently small to a draw a liquid specimen along the flow channel.
Claim 31
Dependent Claim 102 words
A laboratory slide, comprising: a transparent lower slide plate; a bonding agent of precision controlled predetermined thickness disposed directly on said slide plate; and a transparent coverslip secured by direct contact with said bonding agent in overlying relation to and spaced from said slide plate by said bonding agent; said bonding agent being patterned to define an elongated and open-ended flow channel of varying width between said slide plate and coverslip with the flow channel having closed top, bottom and sides; the spacing between said slide plate and coverslip being sufficiently small to a draw a liquid specimen along the flow channel.
Claim 32
Dependent Claim 24 words
The laboratory slide of claim 25 wherein the spacing between said slide plate and coverslip is on the order of 0.003 inch or less.
Claim 33
Dependent Claim 25 words
The laboratory slide of claim 25 wherein the spacing between said coverslip and slide plate varies over at least a portion of said flow channel.
Claim 34
Dependent Claim 93 words
A laboratory slide, comprising: a transparent lower slide plate; bonding means on said slide plate; a transparent coverslip secured in overlying relation to and spaced from said slide plate by said bonding means; said bonding means being patterned to define an elongated and open-ended flow channel between said slide plate and coverslip with the flow channel having closed top, bottom and sides; the spacing between said slide plate and coverslip beng sufficiently small to draw a liquid specimen along the flow channel; and further including at least one reagent along said flow channel.
Claim 35
Dependent Claim 93 words
A laboratory slide, comprising: a transparent lower slide plate; bonding means on said slide plate; a transparent coverslip secured in overlying relation to and spaced from said slide plate by said bonding means; said bonding means being patterned to define an elongated and open-ended flow channel between said slide plate and coverslip with the flow channel having closed top, bottom and sides; the spacing between said slide plate and coverslip beng sufficiently small to draw a liquid specimen along the flow channel; and further including at least one reagent along said flow channel.
Claim 36
Dependent Claim 35 words
The laboratory slide of claim 28 wherein said flow channel comprises at least two flow channel sections, at least one of said flow channel sections having said at least one reagent along the length thereof.
Claim 37
Dependent Claim 17 words
The laboratory slide of claim 28 further including wick means at one end of said flow channel.
Claim 38
Independent Claim 68 words
A method of making a laboratory slide, comprising the steps of: providing a lower slide plate; providing a transparent coverslip; applying a thin adhesive bonding agent to one of the slide plate and coverslip with a thickness on the order of 0.003 inch or less and a pattern to define at least one chamber; and securing the slide plate and coverslip together by means of the bonding agent.
Claim 39
Independent Claim 68 words
A method of making a laboratory slide, comprising the steps of: providing a lower slide plate; providing a transparent coverslip; applying a thin adhesive bonding agent to one of the slide plate and coverslip with a thickness on the order of 0.003 inch or less and a pattern to define at least one chamber; and securing the slide plate and coverslip together by means of the bonding agent.
Claim 40
Dependent Claim 17 words
The method of claim 31 wherein the bonding agent has a thickness of 0.001 inch or less.
Claim 41
Dependent Claim 17 words
The method of claim 32 wherein said step of applying the bonding agent comprises applying an adhesive.
Claim 42
Dependent Claim 36 words
The method of claim 31 wherein said step of applying the bonding agent comprises applying an ink layer and said securing step comprises curing the ink layer into intimate contact with the slide plate and coverslip.
Claim 43
Dependent Claim 23 words
The method of claim 31 further including the step of applying at least one reagent within the chamber prior to said securing step.
Claim 44
Dependent Claim 125 words
A laboratory slide, comprising: a lower slide plate; a transparent coverslip; and an adhesive bonding agent for securing said coverslip in overlying relation upon said slide plate, said bonding agent being interposed directly between said slide plate and coverslip and directly interconnecting said slide plate and coverslip, said bonding agent being patterned to define an elongated and open-ended flow channel, said bonding agent cooperating with said slide plate and coverslip to close the top, bottom and sides of said flow channel, said flow channel having a precision controlled cross sectional size and shape and predetermined spacing dimension between said slide plate and coverslip on the order of about 0.003 inch or less; said bonding agent being patterned to define said flow channel of varying width.
Claim 45
Dependent Claim 125 words
A laboratory slide, comprising: a lower slide plate; a transparent coverslip; and an adhesive bonding agent for securing said coverslip in overlying relation upon said slide plate, said bonding agent being interposed directly between said slide plate and coverslip and directly interconnecting said slide plate and coverslip, said bonding agent being patterned to define an elongated and open-ended flow channel, said bonding agent cooperating with said slide plate and coverslip to close the top, bottom and sides of said flow channel, said flow channel having a precision controlled cross sectional size and shape and predetermined spacing dimension between said slide plate and coverslip on the order of about 0.003 inch or less; said bonding agent being patterned to define said flow channel of varying width.
Claim 46
Dependent Claim 121 words
A laboratory slide, comprising: a lower slide plate; a transparent coverslip; an adhesive bonding agent for securing said coverslip in overlying relation upon said slide plate, said bonding agent being interposed directly between said slide plate and coverslip and directly interconnecting said slide plate and coverslip, said bonding agent being patterned to define an elongated and open-ended flow channel, said bonding agent cooperating with said slide plate and coverslip to close the top, bottom and sides of said flow channel, said flow channel having a precision controlled cross sectional size and shape and predetermined spacing dimension between said slide plate and coverslip on the order of about 0.003 inch or less; and filter means at one end of said flow channel.
Claim 47
Dependent Claim 121 words
A laboratory slide, comprising: a lower slide plate; a transparent coverslip; an adhesive bonding agent for securing said coverslip in overlying relation upon said slide plate, said bonding agent being interposed directly between said slide plate and coverslip and directly interconnecting said slide plate and coverslip, said bonding agent being patterned to define an elongated and open-ended flow channel, said bonding agent cooperating with said slide plate and coverslip to close the top, bottom and sides of said flow channel, said flow channel having a precision controlled cross sectional size and shape and predetermined spacing dimension between said slide plate and coverslip on the order of about 0.003 inch or less; and filter means at one end of said flow channel.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-12-13 1992-06-13 1992-12-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-12-13 1996-06-13 1996-12-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-12-13 2000-06-13 2000-12-13 $7700.00 Window Closed / Lapsed

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