US4789658A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Immunoprophylactic and immunotherapeutic agents
Assignee: Ajinomoto Co Inc
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Filing: 1986-06-09
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Granted: 1988-12-06
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Expires: 2006-06-09
Abstract
Abstract An immunopropylactic and immunotherapeutic agent comprising human interleukin 2 of human cellular origin is disclosed along with a method of producing the agent.
Inventors
- 👤 Ryota Yoshimoto
- 👤 Nobukazu Kashima
- 👤 Junji Hamuro
- 👤 Koji Mitsugi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 14:51
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/52; C07K14/54; C07K14/55; A; A61; A61K; A61K31/00; A61K31/70; A61K31/715; A61K31/716; A61K38/00; A61K38/16; A61K38/17; A61K38/19; A61K38/21; A61P; A61P35/00
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
86 words
An immunoprophylactic and immunotherapeutic agent, composition comprising grade E human interleukin 2 of human T-lymphocyte cell origin, which is substantially free from endotoxins and pyrogens and is wholly or partially in the oxidized state, having a specific activity of at least 2×10 5 units/mg protein, said interleukin 2 showing no cytocidal activity against human lymphocytes in vitro at a concentration of 10 5 units/ml and having substantially no other lymphokine or monokine activity, in combination with an amount of lentinan sufficient to exert synergistic immunological activity.
Claim 2
Dependent Claim
86 words
An immunoprophylactic and immunotherapeutic agent, composition comprising grade E human interleukin 2 of human T-lymphocyte cell origin, which is substantially free from endotoxins and pyrogens and is wholly or partially in the oxidized state, having a specific activity of at least 2×10 5 units/mg protein, said interleukin 2 showing no cytocidal activity against human lymphocytes in vitro at a concentration of 10 5 units/ml and having substantially no other lymphokine or monokine activity, in combination with an amount of lentinan sufficient to exert synergistic immunological activity.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-12-06 | 1992-06-06 | 1992-12-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-12-06 | 1996-06-06 | 1996-12-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-12-06 | 2000-06-06 | 2000-12-06 | $7700.00 | Window Closed / Lapsed |