Protein PP9, process for its enrichment and its isolation and its use

Claim 1

An isolated, concentrated tissue protein, PP 9 , obtained by fractionating an extract of human organs or a solution obtained from such an extract, said tissue protein having: (a) a content of carbohydrates of 5.57±1.35% consisting of 4.9±1.0% of hexoses, 0.1±0.1% of hexosamines, 0.07±0.05% of fucose, and 0.5±0.20 of neuraminic acid; (b) a sedimentation coefficient S 20 ,W of 3.2±0.2 S; (c) a molecular weight of 35,100±3,800 determined in an ultracentrifuge; (d) a molecular weight of 40,000±4,000 determined in a polyacrylamide gel containing sodium dodecyl sulfate; (e) an extinction coefficient E 1 cm 1% (280 nm) of 14.6±1.0; (f) an electrophoretic mobility in the range of the β 1 -globulins; (g) an isoelectric point in a pH range of 5.0-6.8; and (h) an amino acid analysis of ______________________________________ Variation coefficient Mol % (%) ______________________________________ Lysine 8.04 3.49 Histidine 2.58 5.06 Arginine 3.49 1.8 Aspartic acid 10.30 10.45 Threonine 4.29 9.82 Serine 5.7 10.77 Glutamic acid 11.18 2.15 Proline 6.17 13.61 Glycine 5.50 0.79 Alanine 5.69 1.11 Cystine/2 2.29 4.38 Valine 7.12 2.58 Methionine 1.47 9.64 Isoleucine 5.28 5.28 Leucine 10.55 3.23 Tyrosine 3.95 9.68 Phenylalanine 3.87 5.48 Tryptophan 2.36 0.69 ______________________________________