US4775646A
Expired / Lapsed
US
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Fluoride-containing Bioglass™ compositions
Assignee: FLORIDA UNVERSITY OF
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Filing: 1986-09-10
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Granted: 1988-10-04
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Expires: 2006-09-10
Abstract
Abstract A fluoride-containing bioactive glass composition suitable for bulk implant prosthetic devices and coatings for prosthetic devices, the bioactive glass compositions selected from glass formulations containing, by mole 46.1% SiO 2 , 2.6% P 2 O 5 , 26.9% CaO and 24.4% Na 2 O and glass formulations containing, by mole, 52.1% SiO 2 , 23.8% CaO, 21.5% Na 2 O, 2.6% P 2 O 5 wherein, respectively, 30 to 50 molar percent and 40 to 60 molar percent of the CaO is substituted with CaF 2 . These fluoride-containing bioactive glass materials demonstrate high resistance to demineralization in physiological fluids as well as extensive apatite formation which shows a predominance of crystalline apatite of mixed phase character.
Inventors
- 👤 Larry L. Hench
- 👤 Derek B. Spilman
- 👤 June W. Hench
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:21
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/28; A61L27/30; A61L27/32; A61F; A61F2/00; A61F2/02; A61F2/28; A61L27/02; A61L27/12; C; C03; C03C; C03C3/00; C03C3/04; C03C3/076; C03C3/097; C03C4/00; C03C4/0007; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293; A61F2310/00389; A61F2310/00592; A61F2310/00796
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
50 words
A prosthetic device comprising a bioactive glass having the composition of 46.1% SiO 2 , 2.6% P 2 O 5 , 26.9% CaO and 24.4% Na 2 O, said percentages being molar percentages, and further characterized by having about 40 molar percent of the CaO substituted by CaF 2 .
Claim 2
Dependent Claim
50 words
A prosthetic device comprising a bioactive glass having the composition of 46.1% SiO 2 , 2.6% P 2 O 5 , 26.9% CaO and 24.4% Na 2 O, said percentages being molar percentages, and further characterized by having about 40 molar percent of the CaO substituted by CaF 2 .
Claim 3
Dependent Claim
19 words
The prosthetic device of claim 1 wherein said device is a bulk implant consisting essentially of said bioactive glass.
Claim 4
Dependent Claim
18 words
The prosthetic device of claim 1 wherein said device is a prosthetic device coated with said bioactive glass.
Claim 5
Independent Claim
56 words
A method for producing a prosthetic device comprising forming said device from a bioactive glass having the composition 46.1% SiO 2 , 2.6% P 2 O 5 , 26.9% CaO and 24.4% Na 2 O, said percentages being molar percentages, and further characterized by having about 40 percent of the CaO substituted by CaF 2 .
Claim 6
Independent Claim
56 words
A method for producing a prosthetic device comprising forming said device from a bioactive glass having the composition 46.1% SiO 2 , 2.6% P 2 O 5 , 26.9% CaO and 24.4% Na 2 O, said percentages being molar percentages, and further characterized by having about 40 percent of the CaO substituted by CaF 2 .
Claim 7
Dependent Claim
22 words
The method for producing a prostehtic device wherein said device is a bulk implant device comprising said bioactive glass of claim 4.
Claim 8
Dependent Claim
20 words
The method for producing a prosthetic device wherein said device comprises a coating of said bioactive glass of claim 4.
Claim 9
Dependent Claim
45 words
A bioactive glass having the composition 46.1% SiO 2 , 2.6% P 2 O 5 , 26.9% CaO and 24.4% Na 2 O, said percentages being molar percentages, and further characterized by having about 40 molar percent of the CaO substituted by CaF 2 .
Claim 10
Dependent Claim
45 words
A bioactive glass having the composition 46.1% SiO 2 , 2.6% P 2 O 5 , 26.9% CaO and 24.4% Na 2 O, said percentages being molar percentages, and further characterized by having about 40 molar percent of the CaO substituted by CaF 2 .
References Cited (Backward Citations)
US3922155A
Cited
US3981736A
Cited
FR2378733A1
Cited
US4103002A
Cited
US4159358A
Cited
US4234972A
Cited
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