US4772593A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Alkoxysilane compounds in the treatment of swine dysentery
Assignee: Dow Chemical Co
•
Filing: 1985-07-01
•
Granted: 1988-09-20
•
Expires: 2005-07-01
Abstract
Abstract The invention discloses a method of treating swine dysentery by the administration of an animal feed composition containing an effective amount of an alkoxysilane compound such as 3-(triethoxysilyl)propyloctadecyldimethyl ammonium chloride.
Inventors
- 👤 Joseph W. Whalen
- 👤 Edward E. Flagg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 10:01
CPC Classifications
A; A23; A23K; A23K50/00; A23K50/30; A23K20/00; A23K20/10; A23K20/105; A61; A61K; A61K31/00; A61K31/695; C; C07; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/18; C07F7/1804
Claims Analysis
Total Claims: 50
Claim 1
Independent Claim
315 words
A method for treating swine dysentery in swine in need of such treatment which comprises administering to said swine an animal feed composition comprising animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR13## wherein R represents: (a) (R.sup.1 O).sub.3 Si-- wherein each R 1 independently represents a straight or branched alkyl moiety of from 1 to 12 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 12 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 12 hydroxyl groups and 1 to 2 amino groups; (b) ##STR14## wherein each R 2 independently represents H or a straight or branched alkyl moiety of from 1 to 11 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 11 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 11 hydroxyl groups and 1 to 2 amino groups, and R 1 is as defined hereinabove; (c) ##STR15## wherein R 2 is as defined hereinabove; (d) ##STR16## wherein R 3 is a straight or branched alkyl moiety of from 3 to 10 carbon atoms, inclusive, or a cyclic alkyl moiety of from 6 to 10 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 10 hydroxyl groups and 1 to 2 amino groups, and R 1 is as defined hereinabove; (e) ##STR17## wherein R 4 is a straight or branched alkyl moiety of from 2 to 9 carbon atoms, inclusive, or a cyclic alkyl moiety of from 5 to 9 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 9 hydroxyl groups and 1 amino group; (f) ##STR18## wherein R 5 is a straight or branched alkyl moiety of from 1 to 6 carbon atoms, inclusive, optionally substituted with 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 2
Independent Claim
315 words
A method for treating swine dysentery in swine in need of such treatment which comprises administering to said swine an animal feed composition comprising animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR13## wherein R represents: (a) (R.sup.1 O).sub.3 Si-- wherein each R 1 independently represents a straight or branched alkyl moiety of from 1 to 12 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 12 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 12 hydroxyl groups and 1 to 2 amino groups; (b) ##STR14## wherein each R 2 independently represents H or a straight or branched alkyl moiety of from 1 to 11 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 11 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 11 hydroxyl groups and 1 to 2 amino groups, and R 1 is as defined hereinabove; (c) ##STR15## wherein R 2 is as defined hereinabove; (d) ##STR16## wherein R 3 is a straight or branched alkyl moiety of from 3 to 10 carbon atoms, inclusive, or a cyclic alkyl moiety of from 6 to 10 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 10 hydroxyl groups and 1 to 2 amino groups, and R 1 is as defined hereinabove; (e) ##STR17## wherein R 4 is a straight or branched alkyl moiety of from 2 to 9 carbon atoms, inclusive, or a cyclic alkyl moiety of from 5 to 9 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 9 hydroxyl groups and 1 amino group; (f) ##STR18## wherein R 5 is a straight or branched alkyl moiety of from 1 to 6 carbon atoms, inclusive, optionally substituted with 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 3
Independent Claim
101 words
A method for treating swine dysentery in swine in need of such treatment which comprises administering to said swine an animal feed composition comprising animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR19## wherein each T independently represents a straight or branched alkyl moiety of from 1 to 5 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 5 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 5 hydroxyl groups and 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 4
Independent Claim
101 words
A method for treating swine dysentery in swine in need of such treatment which comprises administering to said swine an animal feed composition comprising animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR19## wherein each T independently represents a straight or branched alkyl moiety of from 1 to 5 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 5 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 5 hydroxyl groups and 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 5
Independent Claim
86 words
A method for treating swine dysentery in swine in need of such treatment which comprises administering to said swine an animal feed composition comprising animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR20## wherein each Y independently represents H, or a straight or branched alkyl moiety of from 1 to 3 carbon atoms, inclusive, optionally substituted with 1 to 3 hydroxyl groups and 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 6
Independent Claim
86 words
A method for treating swine dysentery in swine in need of such treatment which comprises administering to said swine an animal feed composition comprising animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR20## wherein each Y independently represents H, or a straight or branched alkyl moiety of from 1 to 3 carbon atoms, inclusive, optionally substituted with 1 to 3 hydroxyl groups and 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 7
Independent Claim
71 words
A method for treating swine dysentery in swine in need of such treatment which comprises administering to said swine an animal feed composition comprising animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR21## wherein Z represents an alkyl moiety of 1 or 2 carbon atoms optionally substituted with 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 8
Independent Claim
71 words
A method for treating swine dysentery in swine in need of such treatment which comprises administering to said swine an animal feed composition comprising animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR21## wherein Z represents an alkyl moiety of 1 or 2 carbon atoms optionally substituted with 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 9
Dependent Claim
9 words
The method of claim 1 wherein X.sup.⊖ is chloride.
Claim 10
Dependent Claim
9 words
The method of claim 2 wherein X.sup.⊖ is chloride.
Claim 11
Dependent Claim
9 words
The method of claim 3 wherein X.sup.⊖ is chloride.
Claim 12
Dependent Claim
9 words
The method of claim 4 wherein X.sup.⊖ is chloride.
Claim 13
Dependent Claim
9 words
The method of claim 2 wherein T is ethyl.
Claim 14
Dependent Claim
13 words
The method of claim 2 wherein T is ethyl and X.sup.⊖ is chloride.
Claim 15
Dependent Claim
9 words
The method of claim 1 wherein R is ##STR22##
Claim 16
Dependent Claim
9 words
The method of claim 1 wherein R is ##STR23##
Claim 17
Dependent Claim
9 words
The method of claim 1 wherein R is ##STR24##
Claim 18
Dependent Claim
37 words
The method of claim 1 wherein said effective amount is from about 500 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,500 ppm.
Claim 19
Dependent Claim
37 words
The method of claim 1 wherein said effective amount is from about 600 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,000 ppm.
Claim 20
Dependent Claim
37 words
The method of claim 2 wherein said effective amount is from about 500 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,500 ppm.
Claim 21
Dependent Claim
37 words
The method of claim 2 wherein said effective amount is from about 600 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,000 ppm.
Claim 22
Dependent Claim
37 words
The method of claim 3 wherein said effective amount is from about 500 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,500 ppm.
Claim 23
Dependent Claim
37 words
The method of claim 3 wherein said effective amount is from about 600 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,000 ppm.
Claim 24
Dependent Claim
37 words
The method of claim 4 wherein said effective amount is from about 500 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,500 ppm.
Claim 25
Dependent Claim
37 words
The method of claim 4 wherein said effective amount is from about 600 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,000 ppm.
Claim 26
Dependent Claim
298 words
An animal feed composition which comprises animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR25## wherein R represents: (a) (R.sup.1 O).sub.3 Si-- wherein each R 1 independently represents a straight or branched alkyl moiety of from 1 to 12 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 12 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 12 hydroxyl groups and 1 to 2 amino groups; (b) ##STR26## wherein each R 2 independently represents H or a straight or branched alkyl moiety of from 1 to 11 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 11 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 11 hydroxyl groups and 1 to 2 amino groups, and R 1 is as defined hereinabove; (c) ##STR27## wherein R 2 is as defined hereinabove; (d) ##STR28## wherein R 3 is a straight or branched alkyl moiety of from 3 to 10 carbon atoms, inclusive, or a cyclic alkyl moiety of from 6 to 10 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 10 hydroxyl groups and 1 to 2 amino groups, and R 1 is as defined hereinabove; (e) ##STR29## wherein R 4 is a straight or branched alkyl moiety of from 2 to 9 carbon atoms, inclusive, or a cyclic alkyl moiety of from 5 to 9 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 9 hydroxyl groups and 1 amino group; or (f) ##STR30## wherein R 5 is a straight or branched alkyl moiety of from 1 to 6 carbon atoms, inclusive, optionally substituted with 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 27
Dependent Claim
298 words
An animal feed composition which comprises animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR25## wherein R represents: (a) (R.sup.1 O).sub.3 Si-- wherein each R 1 independently represents a straight or branched alkyl moiety of from 1 to 12 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 12 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 12 hydroxyl groups and 1 to 2 amino groups; (b) ##STR26## wherein each R 2 independently represents H or a straight or branched alkyl moiety of from 1 to 11 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 11 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 11 hydroxyl groups and 1 to 2 amino groups, and R 1 is as defined hereinabove; (c) ##STR27## wherein R 2 is as defined hereinabove; (d) ##STR28## wherein R 3 is a straight or branched alkyl moiety of from 3 to 10 carbon atoms, inclusive, or a cyclic alkyl moiety of from 6 to 10 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 10 hydroxyl groups and 1 to 2 amino groups, and R 1 is as defined hereinabove; (e) ##STR29## wherein R 4 is a straight or branched alkyl moiety of from 2 to 9 carbon atoms, inclusive, or a cyclic alkyl moiety of from 5 to 9 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 9 hydroxyl groups and 1 amino group; or (f) ##STR30## wherein R 5 is a straight or branched alkyl moiety of from 1 to 6 carbon atoms, inclusive, optionally substituted with 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 28
Dependent Claim
83 words
An animal feed composition which comprises animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR31## wherein each T independently represents a straight or branched alkyl moiety of from 1 to 5 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 5 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 5 hydroxyl groups and 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 29
Dependent Claim
83 words
An animal feed composition which comprises animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR31## wherein each T independently represents a straight or branched alkyl moiety of from 1 to 5 carbon atoms, inclusive, or a cyclic alkyl moiety of from 3 to 5 carbon atoms, inclusive, said alkyl moieties are optionally substituted with 1 to 5 hydroxyl groups and 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 30
Dependent Claim
68 words
An animal feed composition which comprises animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR32## wherein each Y independently represents H, or a straight or branched alkyl moiety of from 1 to 3 carbon atoms, inclusive, optionally substituted with 1 to 3 hydroxyl groups and 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 31
Dependent Claim
68 words
An animal feed composition which comprises animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR32## wherein each Y independently represents H, or a straight or branched alkyl moiety of from 1 to 3 carbon atoms, inclusive, optionally substituted with 1 to 3 hydroxyl groups and 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 32
Dependent Claim
53 words
An animal feed composition which comprises animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR33## wherein Z represents an alkyl moiety of 1 or 2 carbon atoms optionally substituted with 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 33
Dependent Claim
53 words
An animal feed composition which comprises animal feed in admixture with an effective swine dysentery treating amount of at least one of the compounds of the formula: ##STR33## wherein Z represents an alkyl moiety of 1 or 2 carbon atoms optionally substituted with 1 amino group; and X.sup.⊖ is a physiologically acceptable anion.
Claim 34
Dependent Claim
9 words
The composition of claim 22 wherein X.sup.⊖ is chloride.
Claim 35
Dependent Claim
9 words
The composition of claim 23 wherein X.sup.⊖ is chloride.
Claim 36
Dependent Claim
9 words
The composition of claim 24 wherein X.sup.⊖ is chloride.
Claim 37
Dependent Claim
9 words
The composition of claim 25 wherein X.sup.⊖ is chloride.
Claim 38
Dependent Claim
9 words
The composition of claim 23 wherein T is ethyl.
Claim 39
Dependent Claim
13 words
The composition of claim 23 wherein T is ethyl and X.sup.⊖ is chloride.
Claim 40
Dependent Claim
9 words
The composition of claim 22 wherein R is ##STR34##
Claim 41
Dependent Claim
9 words
The composition of claim 22 wherein R is ##STR35##
Claim 42
Dependent Claim
9 words
The composition of claim 22 wherein R is ##STR36##
Claim 43
Dependent Claim
37 words
The composition of claim 22 wherein said effective amount is from about 500 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,500 ppm.
Claim 44
Dependent Claim
37 words
The composition of claim 22 wherein said effective amount is from about 600 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,000 ppm.
Claim 45
Dependent Claim
37 words
The composition of claim 23 wherein said effective amount is from about 500 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,500 ppm.
Claim 46
Dependent Claim
37 words
The composition of claim 23 wherein said effective amount is from about 600 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,000 ppm.
Claim 47
Dependent Claim
37 words
The composition of claim 24 wherein said effective amount is from about 500 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,500 ppm.
Claim 48
Dependent Claim
37 words
The composition of claim 24 wherein said effective amount is from about 600 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,000 ppm.
Claim 49
Dependent Claim
37 words
The composition of claim 25 wherein said effective amount is from about 500 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,500 ppm.
Claim 50
Dependent Claim
37 words
The composition of claim 25 wherein said effective amount is from about 600 parts by weight of the compound or compounds per million parts by weight of the final animal feed composition (ppm) to about 1,000 ppm.
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