US4771077A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Spray dried acetaminophen
Assignee: Wyeth LLC
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Filing: 1986-10-21
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Granted: 1988-09-13
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Expires: 2006-10-21
Abstract
Abstract A therapeutic taste-neutral powder form of acetaminophen obtained by spray-drying a suspension of colloidal silica in a lower alkanol solution of acetaminophen and ethyl cellulose.
Inventors
- 👤 Gerald L. Reuter
- 👤 Robert G. Blank
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 00:08
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0087; A61K9/0095; A61K31/00; A61K31/16; A61K31/165; A61K9/0012; A61K9/0053; A61K9/0056; A61K9/14; A61K9/16; A61K9/1605; A61K9/1611; A61K9/1629; A61K9/1652; A61P; A61P25/00; A61P25/04; A61P29/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
68 words
A therapeutic taste neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 40% to 70% by weight acetaminophen, about 15% to 30% by weight ethyl cellulose and about 15% to 30% by weight colloidal silica, the powder having been spray dried from a suspension of the colloidal silica in a lower alkanol solution of the acetaminophen and ethyl cellulose.
Claim 2
Dependent Claim
68 words
A therapeutic taste neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 40% to 70% by weight acetaminophen, about 15% to 30% by weight ethyl cellulose and about 15% to 30% by weight colloidal silica, the powder having been spray dried from a suspension of the colloidal silica in a lower alkanol solution of the acetaminophen and ethyl cellulose.
Claim 3
Dependent Claim
102 words
In a pharmaceutical dosage form for oral administration as a solid, which dosage form can be disintegrated by water within ten seconds, the improvement which comprises incorporating into such dosage form as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 40% to 70% by weight acetaminophen, about 15% to 30% by weight ethyl cellulose and about 15% to 30% by weight colloidal silica, the powder having been spray dried from a suspension of the colloidal silica in a lower alkanol solution of the acetaminophen and ethyl cellulose.
Claim 4
Dependent Claim
102 words
In a pharmaceutical dosage form for oral administration as a solid, which dosage form can be disintegrated by water within ten seconds, the improvement which comprises incorporating into such dosage form as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 40% to 70% by weight acetaminophen, about 15% to 30% by weight ethyl cellulose and about 15% to 30% by weight colloidal silica, the powder having been spray dried from a suspension of the colloidal silica in a lower alkanol solution of the acetaminophen and ethyl cellulose.
Claim 5
Dependent Claim
14 words
The taste neutral powder of claim 1 wherein the lower alkanol is ethyl alcohol.
Claim 6
Dependent Claim
13 words
The dosage form of claim 2 wherein the lower alkanol is ethyl alcohol.
Claim 7
Dependent Claim
93 words
In a pharmaceutical dosage form for oral administration as a solid chewable taste-newtral tablet containing acetaminophen, the improvement which comprises incorporating into such tablet as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of based upon the weight of the powder, about 40% to 70% by weight acetaminophen, about 15% to 30% by weight ethyl cellulose and about 15% to 30% colloidal silica, the powder having been spray dried from a suspension of the colloidal silica in a lower alkanol solution of the acetaminophen and ethyl cellulose.
Claim 8
Dependent Claim
93 words
In a pharmaceutical dosage form for oral administration as a solid chewable taste-newtral tablet containing acetaminophen, the improvement which comprises incorporating into such tablet as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of based upon the weight of the powder, about 40% to 70% by weight acetaminophen, about 15% to 30% by weight ethyl cellulose and about 15% to 30% colloidal silica, the powder having been spray dried from a suspension of the colloidal silica in a lower alkanol solution of the acetaminophen and ethyl cellulose.
Claim 9
Dependent Claim
12 words
The dosage form of claim 5 wherein the lower alkanol is ethanol.
References Cited (Backward Citations)
US4013785A
Cited
JPS58172311A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-09-13 | 1992-03-14 | 1992-09-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-09-13 | 1996-03-14 | 1996-09-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-09-13 | 2000-03-14 | 2000-09-13 | $7700.00 | Window Closed / Lapsed |