US4767861A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Recovery of benzo-c-phenanthridine alkaloids
Assignee: Vipont Pharmaceutical Inc
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Filing: 1987-08-04
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Granted: 1988-08-30
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Expires: 2007-08-04
Abstract
Abstract A method for extracting benzo-c-phenanthridine alkaloids from plants of the families Papaveracease Fumariaciae, and Berberidacae, comprising extracting ground plant material with acidulated methanol precipitating the extract with an acid salt which is soluble in methanol, redissolving the precipitated salt in water, adding sufficient acid to form a precipitate, and collecting the precipitate so formed. The benzo-c-phenanthridine alkaloids have valuable properties as antimicrobials as well as in treating mouth odors, gingivitis, and periodontitis.
Inventors
- 👤 Richard Boulware
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 02:43
CPC Classifications
C; C07; C07D; C07D221/00; C07D221/02; C07D221/04; C07D221/18
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
57 words
A method for extracting benzo-c-phenanthridine alkaloids from plants of the families Papaveracease, Fumariaceae, and Berberidaceae, comprising grinding the plant, extracting the ground plant with acidulated methanol, precipitating the extract with a zinc salt which is soluble in methanol, redissolving the precipitated salt in water, adding sufficient acid to from a precipitate, and collecting the precipitate so formed.
Claim 2
Independent Claim
57 words
A method for extracting benzo-c-phenanthridine alkaloids from plants of the families Papaveracease, Fumariaceae, and Berberidaceae, comprising grinding the plant, extracting the ground plant with acidulated methanol, precipitating the extract with a zinc salt which is soluble in methanol, redissolving the precipitated salt in water, adding sufficient acid to from a precipitate, and collecting the precipitate so formed.
Claim 3
Dependent Claim
28 words
The method of claim 1 wherein the plants are selected from the group consisting of Sanguinaria canadensis, Macleaya cordata, Corydalis sevtvozii, C. ledebouni, Bocconia frutescens, and Chelidonium majus.
Claim 4
Dependent Claim
11 words
The method of claim 2 wherein the plant is Sanguinaria canadensis.
Claim 5
Dependent Claim
25 words
The method of claim 1 wherein the benzo-c-phenanthridine alkaloids are selected from the group consisting of sanguinarine, chelirubine, sanguirubine, chelilutine, chelerythrine, sanguilutine, and mixtures thereof.
Claim 6
Dependent Claim
25 words
The method of claim 1 wherein the acid salt is selected from the group consisting of zinc chloride, zinc sulfate, zinc iodide, and zinc nitrate.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-08-30 | 1992-02-29 | 1992-08-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-08-30 | 1996-02-29 | 1996-08-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-08-30 | 2000-02-29 | 2000-08-30 | $7700.00 | Window Closed / Lapsed |