Patent US4767789A successfully refreshed from Google Patents.
US4767789A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Spray dried acetaminophen
Assignee: Wyeth LLC
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Filing: 1986-10-21
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Granted: 1988-08-30
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Expires: 2006-10-21
Abstract
Abstract A therapeutic taste-neutral powder form of acetaminophen obtained by spray-drying a suspension of acetaminophen in a solution of ethylcellulose in an organic solvent selective for ethylcellulose.
Inventors
- 👤 Robert G. Blank
- 👤 Dhiraj S. Mody
- 👤 Gary R. Agism
- 👤 Richard J. Kenny
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 19:40
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/16; A61K31/165; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0056; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1652; A61P; A61P25/00; A61P25/04; A61P29/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
73 words
A therapeutic taste neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 76% by weight acetaminophen and about 24% to 40% by weight ethyl cellulose, the powder having been spray dried from a suspension of the acetaminophen in a solution of the ethylcellulose in an organic solvent selective for the ethylcellulose having a solids content of at least about 14% by weight.
Claim 2
Dependent Claim
73 words
A therapeutic taste neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 76% by weight acetaminophen and about 24% to 40% by weight ethyl cellulose, the powder having been spray dried from a suspension of the acetaminophen in a solution of the ethylcellulose in an organic solvent selective for the ethylcellulose having a solids content of at least about 14% by weight.
Claim 3
Dependent Claim
108 words
In a pharmaceutical dosage form for oral administration as a solid, which dosage form can be disintegrated by water within ten seconds, the improvement which comprises incorporating into such dosage form as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 76% by weight acetaminophen and about 24% to 40% by weight of ethyl cellulose, the powder having been spray dried from a suspension of the acetaminophen in a solution of the ethylcellulose in an organic solvent selective for the ethylcellulose having a solids content of at least about 14% by weight.
Claim 4
Dependent Claim
108 words
In a pharmaceutical dosage form for oral administration as a solid, which dosage form can be disintegrated by water within ten seconds, the improvement which comprises incorporating into such dosage form as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 76% by weight acetaminophen and about 24% to 40% by weight of ethyl cellulose, the powder having been spray dried from a suspension of the acetaminophen in a solution of the ethylcellulose in an organic solvent selective for the ethylcellulose having a solids content of at least about 14% by weight.
Claim 5
Dependent Claim
17 words
The taste neutral powder of claim 1 wherein the solvent selective for ethyl cellulose is methylene chloride.
Claim 6
Dependent Claim
37 words
The taste neutral powder of claim 3 wherein the solids content of the suspension of acetaminophen in the solution of ethyl cellulose in methylene chloride is within the range of about 14% to about 19% by weight.
Claim 7
Dependent Claim
16 words
The dosage form of claim 2 wherein the solvent selective for ethyl cellulose is methylene chloride.
Claim 8
Dependent Claim
101 words
In a pharmaceutical dosage form for oral administration as a solid chewable taste-neutral tablet containing acetaminophen, the improvement which comprises incorporating into such tablet as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 76% by weight acetaminophen and about 24% to 40% by weight ethyl cellulose, the powder having been spray dried from a suspension of the acetaminophen in a solution of the ethylcellulose in an organic solvent selective for the ethyl cellulose having a solids content of at least about 14% by weight.
Claim 9
Dependent Claim
101 words
In a pharmaceutical dosage form for oral administration as a solid chewable taste-neutral tablet containing acetaminophen, the improvement which comprises incorporating into such tablet as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 76% by weight acetaminophen and about 24% to 40% by weight ethyl cellulose, the powder having been spray dried from a suspension of the acetaminophen in a solution of the ethylcellulose in an organic solvent selective for the ethyl cellulose having a solids content of at least about 14% by weight.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-08-30 | 1992-02-29 | 1992-08-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-08-30 | 1996-02-29 | 1996-08-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-08-30 | 2000-02-29 | 2000-08-30 | $7700.00 | Window Closed / Lapsed |