US4761373A
Expired / Lapsed
US
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Herbicide resistance in plants
Assignee: MGI Pharma Inc
•
Filing: 1984-08-10
•
Granted: 1988-08-02
•
Expires: 2004-08-10
Abstract
Abstract This invention is directed to the production of plants, plant tissues and plant seeds which are resistant to inhibition by an herbicide which normally inhibits the growth and development of those plants, plant tissues and plant seeds. In particular this invention is directed to altered acetohydroxyacid synthase enzymes which are resistant to inhibition by herbicides which normally inhibit the activity of the synthase before such alteration. This invention further relates to genes encoding such enzymes, and to processes for utilizing these novel genes and enzymes. Further products of the invention include plants, plant tissues and seeds which exhibit resistance to such herbicides resulting from expression of genes encoding herbicide resistant acetohydroxyacid synthase enzyme.
Inventors
- 👤 Paul C. Anderson
- 👤 Kenneth A. Hibberd
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 04:55
CPC Classifications
C; C12; C12N; C12N15/00; C12N15/09; C12N15/11; C12N15/52; A; A01; A01H; A01H1/00; A01H1/06; A01H1/12; A01H1/122; A01H1/123; A01H1/124; A01H5/00; A01H5/10; A01H6/00; A01H6/46; A01H6/4684; C12N15/01; C12N15/63; C12N15/79; C12N15/82; C12N15/8241; C12N15/8261; C12N15/8271; C12N15/8274; C12N15/8278; C12N5/00; C12N5/04; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/948
Claims Analysis
Total Claims: 54
Claim 1
Independent Claim
64 words
A maize plant wherein the growth and development of said plant is resistant to inhibition by a 2-(2-imidazoline-2-yl)pyridine herbicide, or a derivative thereof at levels which normally inhibit the growth and development of said maize plant wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 2
Dependent Claim
64 words
A maize plant wherein the growth and development of said plant is resistant to inhibition by a 2-(2-imidazoline-2-yl)pyridine herbicide, or a derivative thereof at levels which normally inhibit the growth and development of said maize plant wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 3
Dependent Claim
13 words
The maize plant according to claim 1, wherein the herbicide is AC 263,499.
Claim 4
Dependent Claim
13 words
The maize plant according to claim 1, wherein the herbicide is AC 243,997.
Claim 5
Dependent Claim
64 words
A maize plant wherein the growth and development of said plant is resistant to inhibition by a 2-(2-imidazolin-2-yl)quinoline herbicide, or a derivative thereof at levels which normally inhibit the growth and development of said maize plant wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 6
Dependent Claim
64 words
A maize plant wherein the growth and development of said plant is resistant to inhibition by a 2-(2-imidazolin-2-yl)quinoline herbicide, or a derivative thereof at levels which normally inhibit the growth and development of said maize plant wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 7
Dependent Claim
13 words
The maize plant according to claim 4, wherin the herbicide is AC 252,214.
Claim 8
Dependent Claim
60 words
A maize plant wherein the growth and development of said plant is resistant to inhibition by a herbicidal sulfonamide at levels which normally inhibit the growth and development of said maize plant wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said heribicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 9
Dependent Claim
60 words
A maize plant wherein the growth and development of said plant is resistant to inhibition by a herbicidal sulfonamide at levels which normally inhibit the growth and development of said maize plant wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said heribicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 10
Dependent Claim
15 words
The maize plant according to claim 6 wherein the herbicide is a 2-chloro-N [(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl] benzenesulfonamide.
Claim 11
Dependent Claim
56 words
An herbicide resistant maize plant derived from maize cell line XA17, deposited with the ATCC and assigned accession No. 40100, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetogydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 12
Dependent Claim
56 words
An herbicide resistant maize plant derived from maize cell line XA17, deposited with the ATCC and assigned accession No. 40100, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetogydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 13
Dependent Claim
56 words
An herbicide resistant maize plat derived from maize cell line QJ22, deposited with the ATCC and assigned accession No. 40129, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 14
Dependent Claim
56 words
An herbicide resistant maize plat derived from maize cell line QJ22, deposited with the ATCC and assigned accession No. 40129, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 15
Dependent Claim
57 words
An herbicide resistant maize plant derived from maize cell line UV 18, deposited with the ATCC and assigned accession No. 40128, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 16
Dependent Claim
57 words
An herbicide resistant maize plant derived from maize cell line UV 18, deposited with the ATCC and assigned accession No. 40128, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 17
Dependent Claim
56 words
An herbicide resistant maize plant derived from seeds deposited with In Vitro International, Inc. and assigned IVI accession No. 10011, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered actohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 18
Dependent Claim
56 words
An herbicide resistant maize plant derived from seeds deposited with In Vitro International, Inc. and assigned IVI accession No. 10011, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered actohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 19
Dependent Claim
62 words
A maize tissue culture wherein the growth of said tissue culture is resistant to inhibition by a 2-(2-imidozolin-2-yl)pyridine herbicide, or a derivative thereof at levels which normally inhibit the growth of said tissue culture wherein said resistance is conferred by an altered acetohyroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 20
Dependent Claim
62 words
A maize tissue culture wherein the growth of said tissue culture is resistant to inhibition by a 2-(2-imidozolin-2-yl)pyridine herbicide, or a derivative thereof at levels which normally inhibit the growth of said tissue culture wherein said resistance is conferred by an altered acetohyroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 21
Dependent Claim
14 words
The maize tissue culture according to claim 12, wherein the herbicide is AC 263,499.
Claim 22
Dependent Claim
14 words
The maize tissue culture according to claim 12, wherein the herbicide is AC 243,997.
Claim 23
Dependent Claim
60 words
A maize tissue culture wherein the growth of said tissue culture is resistant to inhibition by a 2-(2-imidazolin-2-yl)quinoline herbicide, or a derivative thereof at levels which normally inhibit the growth of said tissue culture wherein said resistance is conferred by acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 24
Dependent Claim
60 words
A maize tissue culture wherein the growth of said tissue culture is resistant to inhibition by a 2-(2-imidazolin-2-yl)quinoline herbicide, or a derivative thereof at levels which normally inhibit the growth of said tissue culture wherein said resistance is conferred by acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 25
Dependent Claim
14 words
The maize tissue culture according to claim 15, wherein the herbicide is AC 252,214.
Claim 26
Dependent Claim
58 words
A maize tissue culture wherein the growth of said tissue culture is resistant to inhibition by a herbicidal sulfonamide at levels which normally inhibit the growth of said tissue culture wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said heribicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 27
Dependent Claim
58 words
A maize tissue culture wherein the growth of said tissue culture is resistant to inhibition by a herbicidal sulfonamide at levels which normally inhibit the growth of said tissue culture wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said heribicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 28
Dependent Claim
15 words
The maize tissue culture according to claim 17 wherein the herbicide is a 2-chloro-N[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbony] benzensulfonamide.
Claim 29
Dependent Claim
57 words
An herbicide resistant maize tissue culture derived from maize cell line XA17, deposisted with the ATCC and assigned accession No. 40100, and mutants, recombinants and geneticallly engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 30
Dependent Claim
57 words
An herbicide resistant maize tissue culture derived from maize cell line XA17, deposisted with the ATCC and assigned accession No. 40100, and mutants, recombinants and geneticallly engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 31
Dependent Claim
57 words
An herbicide resistant maize tissue culture derived from maize cell line QJ22, deposited with the ATCC and assigned accession No. 40129, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 32
Dependent Claim
57 words
An herbicide resistant maize tissue culture derived from maize cell line QJ22, deposited with the ATCC and assigned accession No. 40129, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 33
Dependent Claim
57 words
An heribcide resistant maize tissue culture derived from maize cell line UV18, deposited with the ATCC and assigned accession No. 40128, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 34
Dependent Claim
57 words
An heribcide resistant maize tissue culture derived from maize cell line UV18, deposited with the ATCC and assigned accession No. 40128, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 35
Dependent Claim
57 words
An herbicide resistant maize tissue culture derived from seeds deposited with In Vitro International, Inc. and assigned IVI accession No. 10011, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered actohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 36
Dependent Claim
57 words
An herbicide resistant maize tissue culture derived from seeds deposited with In Vitro International, Inc. and assigned IVI accession No. 10011, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered actohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 37
Dependent Claim
70 words
A maize seed from which a maize plant can be grown wherein the growth and development said plant is resistant to inhibition by a 2-(2-imidozolin-2-yl)pyridine herbicide, or a derivative thereof at levels which normally inhibit the growth and development of said plant wherein said resistance is conferred by an altered acetohyroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 38
Dependent Claim
70 words
A maize seed from which a maize plant can be grown wherein the growth and development said plant is resistant to inhibition by a 2-(2-imidozolin-2-yl)pyridine herbicide, or a derivative thereof at levels which normally inhibit the growth and development of said plant wherein said resistance is conferred by an altered acetohyroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 39
Dependent Claim
13 words
The maize seed according to claim 23, wherein the herbicide is AC 263,499.
Claim 40
Dependent Claim
13 words
The maize seed according to claim 23, wherein the herbicide is AC 243,997.
Claim 41
Dependent Claim
71 words
A maize seed from which a maize plant can be grown wherein the growth and development of said plant is resistant to inhibition by a 2-(2-imidazolin-2-yl)quinoline herbicide, or a derivative thereof at levels which normally inhibit the growth and development of said plant wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 42
Dependent Claim
71 words
A maize seed from which a maize plant can be grown wherein the growth and development of said plant is resistant to inhibition by a 2-(2-imidazolin-2-yl)quinoline herbicide, or a derivative thereof at levels which normally inhibit the growth and development of said plant wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 43
Dependent Claim
13 words
The maize seed according to claim 26, wherein the herbicide is AC 252,214.
Claim 44
Dependent Claim
67 words
A maize seed from which a maize plant can be grown wherein the growth and development of said plant is resistant to inhibition by a herbicidal sulfonamide at levels which normally inhibit the growth and development of said plant wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 45
Dependent Claim
67 words
A maize seed from which a maize plant can be grown wherein the growth and development of said plant is resistant to inhibition by a herbicidal sulfonamide at levels which normally inhibit the growth and development of said plant wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 46
Dependent Claim
14 words
The maize seed aocording to claim 28 wherein the herbicide is a 2-chloro-N[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbony] benzensulfonamide.
Claim 47
Dependent Claim
56 words
An herbicide resistant maize seed derived from maize cell line XA17, deposisted with the ATCC and assigned accession No. 40100, and mutants, recombinants and geneticallly engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 48
Dependent Claim
56 words
An herbicide resistant maize seed derived from maize cell line XA17, deposisted with the ATCC and assigned accession No. 40100, and mutants, recombinants and geneticallly engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 49
Dependent Claim
56 words
An herbicide resistant maize seed derived from maize cell line QJ22, deposited with the ATCC and assigned accession No 40129, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 50
Dependent Claim
56 words
An herbicide resistant maize seed derived from maize cell line QJ22, deposited with the ATCC and assigned accession No 40129, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 51
Dependent Claim
56 words
An heribcide resistant maize seed derived from maize cell line UV18, deposited with the ATCC and assigned accession No. 40128, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid stnthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 52
Dependent Claim
56 words
An heribcide resistant maize seed derived from maize cell line UV18, deposited with the ATCC and assigned accession No. 40128, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid stnthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 53
Dependent Claim
53 words
An herbicide resistant maize seed deposited with In Vitro International, Inc. and assigned IVI accession No. 10011, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
Claim 54
Dependent Claim
53 words
An herbicide resistant maize seed deposited with In Vitro International, Inc. and assigned IVI accession No. 10011, and mutants, recombinants and genetically engineered derivatives thereof wherein said resistance is conferred by an altered acetohydroxyacid synthase resistant to inhibition by said herbicide at levels which normally inhibit the activity of an unaltered acetohydroxyacid synthase.
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