Patent US4760090A successfully refreshed from Google Patents.
US4760090A
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US
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Method of feeding ketoisocaproate to cattle and sheep
Assignee: Iowa State University Research Foundation Inc
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Filing: 1986-03-11
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Granted: 1988-07-26
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Expires: 2006-03-11
Abstract
Abstract Cattle and sheep are fed ketoisocaproate (KIC) with a diet of limited leucine content for enhancement of growth and feed efficiency. The method is especially applicable to beef cattle and sheep being raised for meat production, but it can also be used with veal calves and mature sheep being fed for wool production.
Inventors
- 👤 Steven L. Nissen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 15:04
CPC Classifications
A; A23; A23K; A23K50/00; A23K50/70; A23K50/75; A23K20/00; A23K20/10; A23K20/105; A23K50/10
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
124 words
The method of feeding protein-containing feeds to domestic animals selected from the group consisting of cattle being raised for meat production and sheep being raised for meat and/or wool production to increase the rate of weight gain for the animals being raised for meat production or to increase the amount of wool for the sheep being raised for wool production, wherein the improvement comprises orally administering to said animals from 2 to 1000 milligrams (mg) of alpha-keotisocaproate (KIC) per kilogram (kg) of body weight per 24 hours (hrs) while limiting the dietary intake of leucine to not over 12% of the dry weight of the total protein being fed to the ruminants, said amount of KIC being sodium KIC or the molar equivalent thereof.
Claim 2
Independent Claim
124 words
The method of feeding protein-containing feeds to domestic animals selected from the group consisting of cattle being raised for meat production and sheep being raised for meat and/or wool production to increase the rate of weight gain for the animals being raised for meat production or to increase the amount of wool for the sheep being raised for wool production, wherein the improvement comprises orally administering to said animals from 2 to 1000 milligrams (mg) of alpha-keotisocaproate (KIC) per kilogram (kg) of body weight per 24 hours (hrs) while limiting the dietary intake of leucine to not over 12% of the dry weight of the total protein being fed to the ruminants, said amount of KIC being sodium KIC or the molar equivalent thereof.
Claim 3
Dependent Claim
23 words
The method of claim 1 in which from 10 to 400 mg of KIC are administered per kg body weight per 24 hrs.
Claim 4
Dependent Claim
29 words
The method of claim 1 in which said leucine intake is limited to less than 10% of the dry weight of the total protein being fed to the animals.
Claim 5
Dependent Claim
12 words
The method of claim 1 in which said animals are beef cattle.
Claim 6
Dependent Claim
12 words
The method of claim 1 in which said animals are veal calves.
Claim 7
Dependent Claim
17 words
The method of claim 1 in which said animals are young lambs being raised for meat production.
Claim 8
Dependent Claim
17 words
The method of claim 1 in which said animals are mature sheep being raised for wool production.
Claim 9
Independent Claim
117 words
The method of raising beef cattle to increase the rate of weight gain, said cattle being selected from the group consisting of steers and heifers in which the beef cattle are fed an admixed feed composition containing at least 10% protein by weight on a dry matter basis, wherein the improvement comprises incorporating alpha-ketoisocaproate (KIC) in said feed composition prior to feeding to said beef cattle in an amount of from 0.01 to 2.0 weight percent (wt %) based on the dry weight of the feed composition, said amount of KIC being sodium KIC or the molar equivalent thereof, said feed composition containing not over 12 wt% leucine based on the dry weight of the protein therein.
Claim 10
Independent Claim
117 words
The method of raising beef cattle to increase the rate of weight gain, said cattle being selected from the group consisting of steers and heifers in which the beef cattle are fed an admixed feed composition containing at least 10% protein by weight on a dry matter basis, wherein the improvement comprises incorporating alpha-ketoisocaproate (KIC) in said feed composition prior to feeding to said beef cattle in an amount of from 0.01 to 2.0 weight percent (wt %) based on the dry weight of the feed composition, said amount of KIC being sodium KIC or the molar equivalent thereof, said feed composition containing not over 12 wt% leucine based on the dry weight of the protein therein.
Claim 11
Dependent Claim
25 words
The method of claim 8 in which from 0.5 to 1.5 wt.% of KIC is incorporated in said feed composition based on its dry weight.
Claim 12
Dependent Claim
17 words
The method of claim 8 in which said KIC is in the form of its sodium salt.
Claim 13
Dependent Claim
17 words
The method of claim 8 in which said KIC is in the form of its calcium salt.
Claim 14
Independent Claim
176 words
The method of feeding domestic animals to increase the rate of weight gain for animals being fed for meat production or to increase the amount of wool for sheep being raised for wool production, said animals being selected from the group consisting of (i) steers and heifers being raised for meat production, (ii) veal calves being raised for meat production, and (iii) wethers and ewes being raised for meat and/or wool production, in which the animals are fed an admixed feed composition containing at least 10% protein by weight on a dry matter basis, wherein the improvement comprises incorporating alpha-ketoisocaproate (KIC) in said feed composition prior to feeding to said animals in an amount of from 0.05 to 1.5 weight percent (wt.%) based on the dry weight of the feed composition, said feed composition containing not over 10 wt % leucine based on the dry weight of the protein therein, said KIC being sodium KIC or the molar equivalent amount of calcium KIC, and said KIC being fed in an amount effective for improving protein utilization.
Claim 15
Independent Claim
176 words
The method of feeding domestic animals to increase the rate of weight gain for animals being fed for meat production or to increase the amount of wool for sheep being raised for wool production, said animals being selected from the group consisting of (i) steers and heifers being raised for meat production, (ii) veal calves being raised for meat production, and (iii) wethers and ewes being raised for meat and/or wool production, in which the animals are fed an admixed feed composition containing at least 10% protein by weight on a dry matter basis, wherein the improvement comprises incorporating alpha-ketoisocaproate (KIC) in said feed composition prior to feeding to said animals in an amount of from 0.05 to 1.5 weight percent (wt.%) based on the dry weight of the feed composition, said feed composition containing not over 10 wt % leucine based on the dry weight of the protein therein, said KIC being sodium KIC or the molar equivalent amount of calcium KIC, and said KIC being fed in an amount effective for improving protein utilization.
Claim 16
Dependent Claim
12 words
The method of claim 12 in which said animals are beef cattle.
Claim 17
Dependent Claim
17 words
The method of claim 12 in which said animals are veal calves being raised for meat production.
Claim 18
Dependent Claim
17 words
The method of claim 12 in which said animals are young lambs being raised for meat production.
Claim 19
Dependent Claim
17 words
The method of claim 12 in which said animals are mature sheep being raised for wool production.
Claim 20
Dependent Claim
54 words
The method of claim 1 in which said KIC is orally administered without rumen protection thereof, the amount so administered being effective to increase the rate of weight gain of the animals being raised for meat production, or being effective to increase the amount of wool of the sheep being raised for wool production.
Claim 21
Dependent Claim
54 words
The method of claim 1 in which said KIC is orally administered in a rumen-protected form, the amount so administered being effective to increase the rate of weight gain of the animals being raised for meat production, or being effective to increase the amount of wool of the sheep being raised for wool production.
Claim 22
Dependent Claim
37 words
The method of claim 8 in which said KIC is incorporated in said feed composition without rumen protection thereof, the amount of KIC so incorporated being effective to increase the rate of weight gain of the cattle.
Claim 23
Dependent Claim
37 words
The method of claim 8 in which said KIC is incorporated in said feed composition in a rumen-protected form, the amount of KIC so incorporated being effective to increase the rate of weight gain of the cattle.
Claim 24
Dependent Claim
59 words
The method of claim 12 in which said KIC is incorporated in said feed composition without rumen protection thereof, the amount of KIC so incorporated being effective to increase the rate of weight gain of the animals being fed for meat production, or being effective to increase the amount of wool of the sheep being raised for wool production.
Claim 25
Dependent Claim
59 words
The method of claim 12 in which said KIC is incorporated in said feed composition in a rumen-protected form, the amount of KIC so incorporated being effective to increase the rate of weight gain of the animals being fed for meat production, or being effective to increase the amount of wool of the sheep being raised for wool production.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-07-26 | 1992-01-25 | 1992-07-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-07-26 | 1996-01-25 | 1996-07-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-07-26 | 2000-01-25 | 2000-07-26 | $7700.00 | Window Closed / Lapsed |