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US4757139A
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5-fluoro-2'-deoxyuridine derivative, processes for preparing same and antitumor composition containing the same
Assignee: Teijin Ltd
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Filing: 1984-07-20
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Granted: 1988-07-12
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Expires: 2004-07-20
Abstract
Abstract A 5-fluoro-2'-deoxyuridine derivative expressed by the following formula ##STR1## wherein R 1 and R 2 are the same or different from each other, each representing an alkyl group of 1 to 18 carbon atoms having a carboxyl group as a substituent, or an alkyl group of 9 to 14 carbon atoms, or its pharmacologically acceptable salt as the active ingredient. Said 5-fluoro-2'-deoxyuridine derivative displays a high-level antitumor effect in low doses and shows outstanding safety.
Inventors
- 👤 Takeo Kawaguchi
- 👤 Masahiko Saito
- 👤 Yoshiki Suzuki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 07:00
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/06
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
48 words
The 5-fluoro-2'-deoxyuridine derivative expressed by the following formula (I') ##STR7## wherein R 1 ' and R 2 ' are the same or different from each other, each representing an alkyl group of 1 to 18 carbon atoms having a carboxyl group as substituent, or its pharmacalogically acceptable salt.
Claim 2
Dependent Claim
48 words
The 5-fluoro-2'-deoxyuridine derivative expressed by the following formula (I') ##STR7## wherein R 1 ' and R 2 ' are the same or different from each other, each representing an alkyl group of 1 to 18 carbon atoms having a carboxyl group as substituent, or its pharmacalogically acceptable salt.
References Cited (Backward Citations)
US4097665A
Cited
US4503045A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-07-12 | 1992-01-11 | 1992-07-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-07-12 | 1996-01-11 | 1996-07-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-07-12 | 2000-01-11 | 2000-07-12 | $7700.00 | Window Closed / Lapsed |