Patent US2529010A successfully refreshed from Google Patents.
Patent US4755544A successfully refreshed from Google Patents.
US4755544A
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US
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Sustained release preparation
Assignee: Teijin Ltd
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Filing: 1986-06-04
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Granted: 1988-07-05
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Expires: 2006-06-04
Abstract
Abstract A sustained release preparation comprising: (a) a non-anionic cellulose ether (b) a methoxyethylene-maleic anhydride copolymer or the hydrolyzate thereof, and (c) pharmaceutically active agents. This sustained release preparation can provide the desired sustained-release or dissolution of the pharmaceutically active agents in human organs irrespective of the acidity (i.e., pH conditions) therein.
Inventors
- 👤 Yuji Makino
- 👤 Hideo Matugi
- 👤 Yoshiki Suzuki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 12:56
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/4841; A61K9/4866; A61K9/20; A61K9/2004; A61K9/2022; A61K9/2027; A61K9/205; A61K9/2054
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
40 words
A sustained release preparation comprising: (a) at least one non-anionic cellulose ether, (b) at least one anionic polymer compound selected from the group consisting of methoxyethylene-maleic anhydride copolymers and the hydrolyzates thereof, and (c) at least one pharmaceutically active agent.
Claim 2
Dependent Claim
40 words
A sustained release preparation comprising: (a) at least one non-anionic cellulose ether, (b) at least one anionic polymer compound selected from the group consisting of methoxyethylene-maleic anhydride copolymers and the hydrolyzates thereof, and (c) at least one pharmaceutically active agent.
Claim 3
Dependent Claim
24 words
A sustained release preparation as claimed in claim 1, wherein said non-anionic cellulose ethers are hydroxypropyl cellulose, hydroxypropylmethyl cellulose, methyl cellulose, and ethyl cellulose.
Claim 4
Dependent Claim
34 words
A sustained release preparation as claimed in claim 1, wherein the hydrolyzate of the methoxyethylene-maleic anhydride copolymer is the methoxyethylene-maleic anhydride copolymer of which at least 50% of the maleic anhydride moiety is hydrolyzed.
Claim 5
Dependent Claim
25 words
A sustained release preparation as claimed in claim 1, wherein the weight ratio of the component (b) to the component (a) is 95:5 to 10:90.
Claim 6
Dependent Claim
62 words
A sustained release preparation as claimed in claim 1, wherein the pharmaceutically active agent is at least one member selected from the group consisting of antipyretic, analgesic, or antiphlogistics, antiarrhythmics, hypotensors, vasodilators antiarteriosclerotics, agents for circulatory systems, antitussive expectorants, ulcer preventives, enzyme preparations, antimalignants, chemothoerapeutic agents, antiphlogistic steroid agents, antihistamine agents, local anesthetic agents, mouth disinfection agents, and bone metabolism controlling agents.
Claim 7
Dependent Claim
24 words
A sustained release preparation as claimed in claim 1, which is the form of tablets, granules, grains, powders, dental cones, films, or hard capsules.
Claim 8
Dependent Claim
22 words
A method for administering a sustained release preparation according to claim 1 whereby the pharmaceutically active agent contained therein is gradually released.
Claim 9
Dependent Claim
16 words
A method as claimed in claim 7, wherein the preparation is orally, intraorally or intranasally administered.
References Cited (Backward Citations)
FR2237620A1
Cited
GB1469133A
Cited
US4126672A
Cited
US4172055A
Cited
US4252786A
Cited
US4519801A
Cited
US4627977A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-07-05 | 1992-01-04 | 1992-07-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-07-05 | 1996-01-04 | 1996-07-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-07-05 | 2000-01-04 | 2000-07-05 | $7700.00 | Window Closed / Lapsed |