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Method of desensitizing hypersensitive dentin employing compositions containing potassium chloride

Assignee: Columbia University
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Filing: 1986-04-14
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Granted: 1988-06-14
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Expires: 2006-04-14
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Abstract

Abstract A method for reducing sensory nerve activity in a hypersensitive tooth and for desensitizing hypersensitive dentin involves applying to the surface of exposed dentin of a subject's tooth a potassium salt selected from the group consisting of potassium bicarbonate and potassium chloride in an amount effective to reduce sensory nerve activity and to desensitize hypersensitive dentin of hypersensitive teeth. In the presently preferred embodiment of the invention, potassium bicarbonate is the potassium salt and is applied in a formulation, for example, an aqueous solution containing from about 1.0 to about 360.0 mg of potassium bicarbonate per ml of solution.

Inventors

  • 👤 Syngcuk Kim

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 14:12
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/19; A61K8/20; A61P; A61P1/00; A61P1/02; A61P25/00; A61P25/02; A61Q; A61Q11/00

Claims Analysis

Total Claims: 12
Claim 1
Independent Claim 52 words
A method for reducing sensory nerve activity in a hypersensitive tooth of a subject which comprises applying to the surface of exposed dentin of the hypersensitive tooth a formulation consisting essentially of potassium chloride as the desensitizing agent in an amount effective to reduce the sensory nerve activity of the hypersensitive tooth.
Claim 2
Independent Claim 52 words
A method for reducing sensory nerve activity in a hypersensitive tooth of a subject which comprises applying to the surface of exposed dentin of the hypersensitive tooth a formulation consisting essentially of potassium chloride as the desensitizing agent in an amount effective to reduce the sensory nerve activity of the hypersensitive tooth.
Claim 3
Dependent Claim 13 words
A method according to claim 1, wherein the subject is a human being.
Claim 4
Dependent Claim 17 words
A method according to claim 1, wherein the formulation is a dentrifice, mouthwash or chewing gum formulation.
Claim 5
Dependent Claim 31 words
A method according to claim 1, wherein the formulation is an aqueous solution and the amount of potassium chloride is from about 0.7 mg/ml to about 360 mg/ml of the formulation.
Claim 6
Dependent Claim 21 words
A method according to claim 4, wherein the amount is from about 3.5 mg/ml to about 185 mg/ml of the formulation.
Claim 7
Independent Claim 39 words
A method for desensitizing hypersensitive dentin which comprises applying to the surface of exposed dentin a formulation consisting essentially of potassium chloride as the desensitizing agent in an amount effective to reduce the sensory nerve activity of hypersensitive dentin.
Claim 8
Independent Claim 39 words
A method for desensitizing hypersensitive dentin which comprises applying to the surface of exposed dentin a formulation consisting essentially of potassium chloride as the desensitizing agent in an amount effective to reduce the sensory nerve activity of hypersensitive dentin.
Claim 9
Dependent Claim 13 words
A method according to claim 6, wherein the subject is a human being.
Claim 10
Dependent Claim 17 words
A method according to claim 6, wherein the formulation is a dentrifice, mouthwash or chewing gum formulation.
Claim 11
Dependent Claim 31 words
A method according to claim 6, wherein the formulation is an aqueous solution and the amount of potassium chloride is from about 0.7 mg/ml to about 360 mg/ml of the formulation.
Claim 12
Dependent Claim 21 words
A method according to claim 9, wherein the amount is from about 3.5 mg/ml to about 185 mg/ml of the formulation.

References Cited (Backward Citations)

US380700A Cited
US420186A Cited
US1551638A Cited
US3337404A Cited
US3689636A Cited
US3863006A Cited
US3863006B1 Cited
US4057621A Cited
US4327079A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-06-14 1991-12-14 1992-06-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-06-14 1995-12-14 1996-06-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-06-14 1999-12-14 2000-06-14 $7700.00 Window Closed / Lapsed

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