US4747683A — Method and device for in vivo wetting determinati…

Claim 1

Independent Claim 91 words

A method of measuring the in vivo wetting quality of a contact lens worn by a subject, such method comprising the steps of supporting the subject's head so as to maintain the lens in a fixed location illuminating the pre-lens tear film with coherent light recording a time sequence image of the pattern of interference bands formed by specular reflectance of the light from the pre-lens film, and correlating the position of sequential recorded images of at least one interference band so as to obtain a measurement of said wetting quality.

Claim 2

Independent Claim 91 words

A method of measuring the in vivo wetting quality of a contact lens worn by a subject, such method comprising the steps of supporting the subject's head so as to maintain the lens in a fixed location illuminating the pre-lens tear film with coherent light recording a time sequence image of the pattern of interference bands formed by specular reflectance of the light from the pre-lens film, and correlating the position of sequential recorded images of at least one interference band so as to obtain a measurement of said wetting quality.

Claim 3

Dependent Claim 40 words

The method of claim 1 wherein the step of correlating includes the step of determining the spacing between adjacent pairs of interference bands proximate to an edge of the film, and wherein the measured wetting quality is the contact angle.

Claim 4

Dependent Claim 53 words

The method of claim 1 wherein the step of correlating includes correlating the sequential motion of interference bands past a fixed position so as to identify the formation of a dry spot, and wherein the measured wetting quality is the time interval between the subject's blink and the onset of tear film break-up.

Claim 5

Dependent Claim 33 words

The method of claim 1, wherein the step of corrolating includes comparing local irregularities in the interference pattern at different locations on the lens to determine the existence of variations in wetting quality.

Claim 6

Dependent Claim 25 words

The method of claim 1 further including the step of treating the lens with a treatment fluid before performing said steps of recording and correlating.

Claim 7

Dependent Claim 66 words

The method of claim 5 wherein the step of correlating includes correlating so as to obtain a measurement of a said quality for a new lens, correlating so as to obtain a measurement of the same quality for a lens which has been worn for a known time interval, and comparing the two said measurements to develop a measurement of change in the said wetting quality.

Claim 8

Independent Claim 82 words

A method of determining a wetting quality of a contact lens worn by a subject, such method comprising the steps of supporting the subject's head so as to determine a fixed location of the contact lens illuminating the pre-lens tear film with coherent light recording a time sequence image of the light specularly reflected by the tear film and determining the tear film thickness from the recorded time sequence image, said thickness at a particular time being indicative of the wetting quality.

Claim 9

Independent Claim 82 words

A method of determining a wetting quality of a contact lens worn by a subject, such method comprising the steps of supporting the subject's head so as to determine a fixed location of the contact lens illuminating the pre-lens tear film with coherent light recording a time sequence image of the light specularly reflected by the tear film and determining the tear film thickness from the recorded time sequence image, said thickness at a particular time being indicative of the wetting quality.

Claim 10

Dependent Claim 181 words

Apparatus for the evaluation of an ophthalmic wetting characteristic, such wetting characteristic being a function of tear film thickness, wherein the apparatus comprises light means for directing incident light at a tear film on a subject's eye when the subject's head is supported in an observation position, and light collection means for collecting incident light which has been specularly reflected from, and for focusing an image of a surface region of, the tear film, for providing an image of the tear film, such image including a pattern of interference bands localized in said tear film surface region and formed by interference between incident light reflected from front and rear surfaces of said tear film so as to be indicative of tear film thickness, such light means and light collection means being arranged such that the light from the tear film collected and focused by the collection means consists substantially of light specularly reflected from the tear film whereby the interference bands are clearly defined throughout the region, thus enabling the wetting characteristic to be evaluated by determining the thickness over time.

Claim 11

Dependent Claim 181 words

Apparatus for the evaluation of an ophthalmic wetting characteristic, such wetting characteristic being a function of tear film thickness, wherein the apparatus comprises light means for directing incident light at a tear film on a subject's eye when the subject's head is supported in an observation position, and light collection means for collecting incident light which has been specularly reflected from, and for focusing an image of a surface region of, the tear film, for providing an image of the tear film, such image including a pattern of interference bands localized in said tear film surface region and formed by interference between incident light reflected from front and rear surfaces of said tear film so as to be indicative of tear film thickness, such light means and light collection means being arranged such that the light from the tear film collected and focused by the collection means consists substantially of light specularly reflected from the tear film whereby the interference bands are clearly defined throughout the region, thus enabling the wetting characteristic to be evaluated by determining the thickness over time.

Claim 12

Dependent Claim 50 words

Apparatus according to claim 8, wherein the light means directs coherent light at the eye, and wherein the light collection means includes a motion picture camera focused on the tear film and positioned to image the light from the light means specularly reflected from the tear film over said region.

Claim 13

Dependent Claim 16 words

Apparatus according to claim 9, wherein the light means directs substantially monochromatic light at the eye.

Claim 14

Dependent Claim 48 words

Apparatus according to claim 10, wherein the light means directs the light at the eye via converging optics having a central aperture, and the camera images the prelens tear film through said central aperture, whereby the camera images specularly reflected light from a region of the tear film.

Claim 15

Dependent Claim 12 words

Apparatus according to claim 8, wherein the light means includes a laser.

Claim 16

Dependent Claim 128 words

Apparatus for the evaluation of a wetting characteristic of a contact lens being worn by a subject, such wetting characteristic being a function of prelens tear film thickness, wherein the apparatus comprises means for supporting the subject's head so as to determine a fixed location of the contact lens, light means for directing coherent light at the lens, means for recording a time sequence image of the light specularly reflected from the prelens tear film, such image including a pattern of interference bands indicative of tear film thickness, and means operative on the time sequence recording of the image for determining time and space coordinates of the recorded interference bands, and for developing output signals indicative thereof whereby the wetting characteristic may be evaluated by determining the thickness.

Claim 17

Dependent Claim 128 words

Apparatus for the evaluation of a wetting characteristic of a contact lens being worn by a subject, such wetting characteristic being a function of prelens tear film thickness, wherein the apparatus comprises means for supporting the subject's head so as to determine a fixed location of the contact lens, light means for directing coherent light at the lens, means for recording a time sequence image of the light specularly reflected from the prelens tear film, such image including a pattern of interference bands indicative of tear film thickness, and means operative on the time sequence recording of the image for determining time and space coordinates of the recorded interference bands, and for developing output signals indicative thereof whereby the wetting characteristic may be evaluated by determining the thickness.

Claim 18

Dependent Claim 19 words

Apparatus according to claim 13, further including computer means for computing the wetting characteristic from the said output signals.

Claim 19

Dependent Claim 32 words

Apparatus according to claim 14, wherein the means for determining coordinates determines coordinates of consecutive interference bands along line normal to a dry edge, and wherein the computer computes the contact angle.

Claim 20

Dependent Claim 169 words

Apparatus for the evaluation of a wetting characterstic of a contact lens being worn by a subject, such wetting characteristic being a function of prelens tear film thickness, wherein the apparatus comprises means for supporting the subject's head so as to determine a fixed location of the contact lens, light means for directing a scanning beam of coherent light at the lens via a first scanning mirror such that the light strikes a point x on the lens at an angle φ(x) to the normal, a second scanning mirror controlled to scan the point x in synchrony with the first mirror so as to receive light reflected from the point x at the angle φ(x), and camera means located to receive the light reflected from the second scanning mirror, for recording a time sequence image of the light specularly reflected from the prelens tear film, such image including a pattern of interference bands indicative of tear film thickness, whereby the wetting characteristic may be evaluated by determining the thickness.

Claim 21

Dependent Claim 169 words

Apparatus for the evaluation of a wetting characterstic of a contact lens being worn by a subject, such wetting characteristic being a function of prelens tear film thickness, wherein the apparatus comprises means for supporting the subject's head so as to determine a fixed location of the contact lens, light means for directing a scanning beam of coherent light at the lens via a first scanning mirror such that the light strikes a point x on the lens at an angle φ(x) to the normal, a second scanning mirror controlled to scan the point x in synchrony with the first mirror so as to receive light reflected from the point x at the angle φ(x), and camera means located to receive the light reflected from the second scanning mirror, for recording a time sequence image of the light specularly reflected from the prelens tear film, such image including a pattern of interference bands indicative of tear film thickness, whereby the wetting characteristic may be evaluated by determining the thickness.

Annuity Stage	Window Opens	Payment Deadline	Surcharge Period Until	Estimated Fee	Status
3.5 Years (Year 4)	1991-05-31	1991-11-30	1992-05-31	$2000.00	Window Closed / Lapsed
7.5 Years (Year 8)	1995-05-31	1995-11-30	1996-05-31	$3760.00	Window Closed / Lapsed
11.5 Years (Year 12)	1999-05-31	1999-11-30	2000-05-31	$7700.00	Window Closed / Lapsed

Method and device for in vivo wetting determinations

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