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US4740374A
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US
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Anti-inflammatory analgesic adhesive preparation
Assignee: Nitto Denko Corp
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Filing: 1986-10-09
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Granted: 1988-04-26
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Expires: 2006-10-09
Abstract
Abstract An anti-inflammatory analgesic adhesive preparation is disclosed, comprising a flexible support having laminated thereon a pressure-sensitive adhesive material layer which contains a non-steroidal anti-inflammatory analgesic agent having salt form and an organic acid. This adhesive preparation has excellent percutaneous absorption properties.
Inventors
- 👤 Yoshihisa Nakano
- 👤 Kazuhisa Ninomiya
- 👤 Tetuo Horiuchi
- 👤 Yuichi Inoue
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 12:09
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7053; A61K47/00; A61K47/06; A61K47/08; A61K47/12; A61K9/7061; A61L; A61L15/00; A61L15/16; A61L15/42; A61L15/58; A61P; A61P29/00
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
35 words
An anti-inflammatory analgesic adhesive preparation comprising a flexible support having laminated thereon a pressure-sensitive adhesive material layer which contains a non-steroidal anti-inflammatory analgesic agent having a salt form and a pharmaceutically acceptable organic carboxylic acid.
Claim 2
Dependent Claim
35 words
An anti-inflammatory analgesic adhesive preparation comprising a flexible support having laminated thereon a pressure-sensitive adhesive material layer which contains a non-steroidal anti-inflammatory analgesic agent having a salt form and a pharmaceutically acceptable organic carboxylic acid.
Claim 3
Dependent Claim
42 words
The preparation as in claim 1, wherein the non-steroidal anti-inflammatory analgesic agent having a salt form is at least one member selected from the group consisting of tolmetin sodium fenoprofen calcium, sodium meclofenamate, amfenac sodium, zomepirac sodium, loxoprofen sodium, and aluminum flufenamate.
Claim 4
Dependent Claim
32 words
The preparation as in claim 1, wherein the carboxylic acid is selected from the group consisting of citric acid, succinic acid, tartaric acid, maleic acid, fumaric acid, salicylic acid and acetic acid.
Claim 5
Dependent Claim
35 words
The preparation as in claim 1, wherein the amount of the organic acid is 5 to 100 parts by weight per 100 parts by weight of the non-steroidal anti-inflammatory analgesic agent having a salt form.
Claim 6
Dependent Claim
35 words
The preparation as in claim 4, wherein the amount of the organic acid is 10 to 50 parts by weight per 100 parts by weight of the non-steroidal anti-inflammatory analgesic agent having a salt form.
Claim 7
Dependent Claim
34 words
The preparation as in claim 1, wherein the amount of the non-steroidal anti-inflammatory analgesic agent having a salt form is 1 to 40% by weight based on the weight of the pressure-sensitive adhesive material.
Claim 8
Dependent Claim
34 words
The preparation as in claim 6, wherein the amount of the non-steroidal anti-inflammatory analgesic agent having a salt form is 5 to 30% by weight based on the weight of the pressure-sensitive adhesive material.
Claim 9
Dependent Claim
26 words
The preparation as in claim 1, wherein the amount of the non-steroidal anti-inflammatory analgesic agent having a salt form is 20 to 1,600 μg/cm 2 .
Claim 10
Dependent Claim
26 words
The preparation as in claim 8, wherein the amount of the non-steroidal anti-inflammatory analgesic agent having a salt form is 100 to 1,200 μg/cm 2 .
Claim 11
Dependent Claim
17 words
The preparation as in claim 1, wherein the pressure-sensitive adhesive material is an acrylic pressure-sensitive adhesive material.
Claim 12
Dependent Claim
39 words
The preparation as in claim 10, wherein the acrylic pressure-sensitive adhesive material is a copolymer of an alkyl ester of (meth)acrylic acid, an alkyl ester of (meth)acrylic acid containing an ether bond in the molecule, and other copolymerizable monomer.
Claim 13
Dependent Claim
39 words
The preparation as in claim 11, wherein the proportion of the alkyl ester of (meth)acrylic acid/the alkyl ester of (meth)acrylic acid containing an ether bond in the molecular/the other copolymerizable monomer is 40 to 80/59 to 10/1 to 40.
References Cited (Backward Citations)
EP0042290A2
Cited
EP0156080A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-04-26 | 1991-10-26 | 1992-04-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-04-26 | 1995-10-26 | 1996-04-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-04-26 | 1999-10-26 | 2000-04-26 | $7700.00 | Window Closed / Lapsed |