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US4737342A Expired / Lapsed US ⏱️ 0.0 years remaining

Test module

Assignee: Bayer Corp
•
Filing: 1982-08-06
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Granted: 1988-04-12
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Expires: 2002-08-06
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Abstract

Abstract A test module or reagent handling device for use with a clinical analyzer for conducting body serum assays and/or immunoassays; the test module coacting with the analyzer to selectively provide a plurality of liquid dilution and reagent materials to a serum sample, the test module having programmable valve means coacting with a dispense probe to serially: select a serum sample and to deposit said sample and liquid dilution material into a dilution cup or vessel; subsequentially withdraw a portion of the diluted serum from the dilution cup and to dispense said diluted serum portion along with at least one liquid reagent material into a reaction cup or vessel.

Inventors

  • 👤 Raymond J. Herrmann
  • 👤 Harry F. DeBevec
  • 👤 Randolph F. Bradshaw
  • 👤 Peter O. Botten

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-05 19:50
CPC Classifications
G; G01; G01N; G01N35/00; G01N35/10; G01N35/1081; G01N35/1083

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 251 words
A clinical analyzer instrument for spectrophotometrically assaying a liquid blood serum sample having; a reaction vessel, a sample vessel, a dilution vessel, a transport means for carrying the reaction vessel to a reading station, a dispensing probe, a means to withdraw and deposit a sample, and a microprocessor control means for dispensing serum samples, dilution materials, and liquid reagents into and out of these vessels; the improvement being a serial analyzer comprising: (a) a control valve means having a plurality of connection ports wherein a main connection port can communicate with any other single port; (b) a means connecting the valve means to the dispensing probe; (c) a means for connecting a diluent source to the control valve means; (d) a means for connecting at least one reagent source to the control valve means which is separate from the diluent source connection means; (e) a means for connecting the main port of the control valve means to the sample withdrawal and deposit means; (f) the transport means having a rotary motion, and separate serum, dilution, and reaction vessels being positioned thereon in a radial relationship; (g) a means for horizontally and vertically moving the dispensing probe whereby it can be positioned into a radially-spaced serum vessel to withdraw a sample, into a radially-spaced dilution vessel, first to deposit the sample and diluents, then to withdraw the diluted sample, and finally, into a radially-spaced reaction vessel to deposit at least a reagent and the diluted sample; and (h) a valve actuation means.
Claim 2
Dependent Claim 251 words
A clinical analyzer instrument for spectrophotometrically assaying a liquid blood serum sample having; a reaction vessel, a sample vessel, a dilution vessel, a transport means for carrying the reaction vessel to a reading station, a dispensing probe, a means to withdraw and deposit a sample, and a microprocessor control means for dispensing serum samples, dilution materials, and liquid reagents into and out of these vessels; the improvement being a serial analyzer comprising: (a) a control valve means having a plurality of connection ports wherein a main connection port can communicate with any other single port; (b) a means connecting the valve means to the dispensing probe; (c) a means for connecting a diluent source to the control valve means; (d) a means for connecting at least one reagent source to the control valve means which is separate from the diluent source connection means; (e) a means for connecting the main port of the control valve means to the sample withdrawal and deposit means; (f) the transport means having a rotary motion, and separate serum, dilution, and reaction vessels being positioned thereon in a radial relationship; (g) a means for horizontally and vertically moving the dispensing probe whereby it can be positioned into a radially-spaced serum vessel to withdraw a sample, into a radially-spaced dilution vessel, first to deposit the sample and diluents, then to withdraw the diluted sample, and finally, into a radially-spaced reaction vessel to deposit at least a reagent and the diluted sample; and (h) a valve actuation means.
Claim 3
Dependent Claim 28 words
In a clinical analyzer as is defined in claim 1 and wherein means are provided for connecting at least two liquid reagent materials separately to the valve means.
Claim 4
Dependent Claim 44 words
The clinical analyzer of claim 1 wherein: (a) the transport means is annular; and (b) the dispensing probe, the sample withdrawal and deposit means, the control valve means, and the dispensing probe movement means are within the central opening of the annular transport means.
Claim 5
Dependent Claim 27 words
A clinical analyzer as defined in claim 1 and wherein the means in said valve means further comprises a valve plug member rotatably mounted in a housing.
Claim 6
Dependent Claim 32 words
A clinical analyzer as defined in claim 4 and wherein the valve plug member is provided with channel means selectively communicatable with each said port means upon rotation of said plug member.
Claim 7
Dependent Claim 17 words
A clinical analyzer as defined in claim 1 and wherein the valve actuating means comprises motor means.
Claim 8
Dependent Claim 28 words
A clinical analyzer as defined in claim 6 and wherein the motor means is a step motor actuatable to sequentially step the valve means along a predetermined path.
Claim 9
Dependent Claim 37 words
A clinical analyzer as is defined in claim 1 having an encoder means adapted to coact with the control valve means of said analyzer and operable to cause a predetermined sequence of actuation to said valve means.
Claim 10
Dependent Claim 24 words
A clinical analyzer as is defined in claim 8 and wherein the encoder means has sensor means adapted to coact with the control means.

References Cited (Backward Citations)

US3449959A Cited
US3536450A Cited
CA950703A Cited
US3802782A Cited
US3788816A Cited
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US4315891A Cited
US4322216A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-04-12 1991-10-12 1992-04-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-04-12 1995-10-12 1996-04-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-04-12 1999-10-12 2000-04-12 $7700.00 Window Closed / Lapsed

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