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US4737284A Expired / Lapsed US ⏱️ 0.0 years remaining

Chromatography column

Assignee: Merck Patent GmbH
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Filing: 1986-06-02
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Granted: 1988-04-12
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Expires: 2006-06-02
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Abstract

Abstract The invention relates to a chromatography columns, consisting of metal tubes which are filled with sorbent and which are provided at both ends with distributed and sealing elements. Screw unions for connecting capillaries are utilized, which unions consist at least of a supporting nut fitted to the column tube and a cap nut. The supporting nuts consist of two half-shells which can be removed from the column tube after the cap nut has been unscrewed. By so configuring the columns, the same tube column can optionally accommodate precolumns.

Inventors

  • 👤 Gunter Hauke
  • 👤 Gunter Sattler

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 06:17
CPC Classifications
G; G01; G01N; G01N30/00; G01N30/02; G01N30/60; G01N30/6034; G01N30/6039; G01N30/04; G01N30/06; G01N30/08; G01N2030/085; G01N30/6004; G01N30/6017; G01N30/6026; G01N30/603

Claims Analysis

Total Claims: 2
Claim 1
Independent Claim 238 words
A chromatography column supply system wherein there are a plurality of chromatography columns containing sorbent and a lesser number of chromatography precolumns configured for use with some of the chromatogaphy columns, the improvement comprising: each chromatography column having first and second ends which are identical, the ends each column including an external groove and having internal, outwaradly facing shoulders; identical support nuts for each end, each support nut comprising two mirror image half-shells each having an internally projecting semicircular rib which is received in one half of the groove; a distribution element positioning in each column in abuttment with one of the shoulders and in engagement with the sorbent in the column; a thrust member for each column; the thrust member engaging the distribution element if the column does not use a precolumn, and engaging the precolumn if the column uses a precolumn; first cap nuts having selected lengths, internal threads for threadably engaging with the support nuts, and shoulders for engaging the thrust members to urge the thrust members into abutment with distribution element, and second cap nuts each having a length greater than the length of the first cap nuts, internal threads for threadably engaging the external threads of the support nuts and shoulders for engaging thrust members to urge the thrust members into abutment with precolumns; whereby more than one type of chromatography column need not be stocked for use either with or without precolumns.
Claim 2
Dependent Claim 238 words
A chromatography column supply system wherein there are a plurality of chromatography columns containing sorbent and a lesser number of chromatography precolumns configured for use with some of the chromatogaphy columns, the improvement comprising: each chromatography column having first and second ends which are identical, the ends each column including an external groove and having internal, outwaradly facing shoulders; identical support nuts for each end, each support nut comprising two mirror image half-shells each having an internally projecting semicircular rib which is received in one half of the groove; a distribution element positioning in each column in abuttment with one of the shoulders and in engagement with the sorbent in the column; a thrust member for each column; the thrust member engaging the distribution element if the column does not use a precolumn, and engaging the precolumn if the column uses a precolumn; first cap nuts having selected lengths, internal threads for threadably engaging with the support nuts, and shoulders for engaging the thrust members to urge the thrust members into abutment with distribution element, and second cap nuts each having a length greater than the length of the first cap nuts, internal threads for threadably engaging the external threads of the support nuts and shoulders for engaging thrust members to urge the thrust members into abutment with precolumns; whereby more than one type of chromatography column need not be stocked for use either with or without precolumns.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-04-12 1991-10-12 1992-04-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-04-12 1995-10-12 1996-04-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-04-12 1999-10-12 2000-04-12 $7700.00 Window Closed / Lapsed

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