US4717718A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for the controlled delivery of a beneficial agent
Assignee: Alza Corp
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Filing: 1986-08-11
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Granted: 1988-01-05
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Expires: 2006-08-11
Abstract
Abstract A device for the controlled delivery of a beneficial agent is disclosed. The device comprises (a) a formulation layer and (b) a layer comprising means for pushing the formualtion layer from said device. The formulation layer comprises the beneficial agent avermectin or ivermectin.
Inventors
- 👤 James B. Eckenhoff
- 👤 Richard Cortese
- 👤 Felix A. Landrau
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 17:55
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0002; A61K9/0004; A61M; A61M31/00; A61M31/002
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
48 words
A device for the controlled delivery of a beneficial agent comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the formulation layer comprises the beneficial agent avermectin and a copolymer of 1,2-butylene oxide and ethylene oxide.
Claim 2
Independent Claim
48 words
A device for the controlled delivery of a beneficial agent comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the formulation layer comprises the beneficial agent avermectin and a copolymer of 1,2-butylene oxide and ethylene oxide.
Claim 3
Independent Claim
75 words
A device for the controlled delivery of a beneficial agent comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the formulation layer comprises a beneficial agent selected from the group consisting of avermectin and ivermectin, and a member selected from the group consisting of a monoglyceride of a fatty acid, a diglyceride of a fatty acid, and a triglyceride of a fatty acid.
Claim 4
Independent Claim
75 words
A device for the controlled delivery of a beneficial agent comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the formulation layer comprises a beneficial agent selected from the group consisting of avermectin and ivermectin, and a member selected from the group consisting of a monoglyceride of a fatty acid, a diglyceride of a fatty acid, and a triglyceride of a fatty acid.
Claim 5
Dependent Claim
72 words
A delivery device for the controlled administration of a beneficial agent comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the formulation layer comprises a beneficial agent selected from the group consisting of avermectin and ivermectin, and a member selected from the group consisting of partially hydrogenated plant, vegetable and animal fats, and completely hydrogenated plant, vegetable and animal fats.
Claim 6
Dependent Claim
72 words
A delivery device for the controlled administration of a beneficial agent comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the formulation layer comprises a beneficial agent selected from the group consisting of avermectin and ivermectin, and a member selected from the group consisting of partially hydrogenated plant, vegetable and animal fats, and completely hydrogenated plant, vegetable and animal fats.
Claim 7
Dependent Claim
70 words
A delivery device for the controlled administration of a beneficial agent comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the formulation layer comprises a beneficial agent selected from the group consisting of avermectin and ivermectin and a member selected from the group consisting of an alkylene glycol fatty acid ester, and a polyalkylene glycol fatty acid ester.
Claim 8
Dependent Claim
70 words
A delivery device for the controlled administration of a beneficial agent comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the formulation layer comprises a beneficial agent selected from the group consisting of avermectin and ivermectin and a member selected from the group consisting of an alkylene glycol fatty acid ester, and a polyalkylene glycol fatty acid ester.
Claim 9
Dependent Claim
42 words
A delivery device for the controlled administration of a beneficial agent comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and wherein the formulation layer comprises avermectin and a pharmaceutically acceptable wax.
Claim 10
Dependent Claim
42 words
A delivery device for the controlled administration of a beneficial agent comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and wherein the formulation layer comprises avermectin and a pharmaceutically acceptable wax.
Claim 11
Dependent Claim
40 words
The delivery device for the controlled administration of the beneficial agent according to claim 5, comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the avermectin is ivermectin.
Claim 12
Dependent Claim
46 words
The delivery device for the controlled administration of a beneficial agent according to claim 5, comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; wherein the wax softens continuously at a temperature greater than 25° C.
Claim 13
Dependent Claim
68 words
A delivery device for the controlled dispensing of a beneficial agent to an environment of use comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the formulation layer comprises (c) an avermectin and (d) means for absorbing heat from the environment of use for dispensing the avermectin from the delivery device to the environment of use.
Claim 14
Dependent Claim
68 words
A delivery device for the controlled dispensing of a beneficial agent to an environment of use comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and, wherein the formulation layer comprises (c) an avermectin and (d) means for absorbing heat from the environment of use for dispensing the avermectin from the delivery device to the environment of use.
Claim 15
Dependent Claim
82 words
A delivery device for the controlled dispensing of a beneficial agent to an environment of use having a temperature greater than 25° C. comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and wherein the formulation layer comprises means for absorbing thermal energy from the environment for forming a carrier for dispensing a beneficial agent to the environment, and a dosage unit amount of the beneficial agent ivermectin present in the means.
Claim 16
Dependent Claim
82 words
A delivery device for the controlled dispensing of a beneficial agent to an environment of use having a temperature greater than 25° C. comprising: (a) a formulation layer and (b) a layer comprising means for pushing the formulation layer from said device; and wherein the formulation layer comprises means for absorbing thermal energy from the environment for forming a carrier for dispensing a beneficial agent to the environment, and a dosage unit amount of the beneficial agent ivermectin present in the means.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-01-04 | 1991-07-06 | 1992-01-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-01-04 | 1995-07-06 | 1996-01-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-01-04 | 1999-07-06 | 2000-01-05 | $7700.00 | Window Closed / Lapsed |