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Device and method for chemical analysis of fluids with a reagent coated light source

Assignee: Bayer Corp
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Filing: 1986-09-11
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Granted: 1988-01-05
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Expires: 2006-09-11
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Abstract

Abstract A device for measuring transmittance of light comprises a light source, photodetector and signal processor. The concentration of a substance in a fluid sample can be accurately determined by coating the light source with a reagent that is chemically reactive with the substance and measuring light transmitted from the coating before and after the substance is applied to the coating. The coating can contain a solid support matrix, such as a translucent nonwoven paper web of the type used in reagent test strips and similar indicator devices. The invention is useful for making clinical analyses on body fluids.

Inventors

  • 👤 David A. N. Morris

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 04:06
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/75; G01N21/17; G01N21/25; G01N21/255; Y; Y10; Y10S; Y10S435/00; Y10S435/808; Y10S436/00; Y10S436/805

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 108 words
A device for determining the presence or concentration of a ligand in a specimen by measuring light, wherein the device consisting essentially of light source means for providing illumination; light responsive means for generating an electrical signal in response to light; and means for measuring the electrical signal from the light responsive means; wherein the light source has an end surface through which or from which light passes; and said end surface contains a reagent that is chemically reactive with a ligand in a specimen; and light from the light source passes through the end surface and through or from the end surface to the light responsive means.
Claim 2
Independent Claim 108 words
A device for determining the presence or concentration of a ligand in a specimen by measuring light, wherein the device consisting essentially of light source means for providing illumination; light responsive means for generating an electrical signal in response to light; and means for measuring the electrical signal from the light responsive means; wherein the light source has an end surface through which or from which light passes; and said end surface contains a reagent that is chemically reactive with a ligand in a specimen; and light from the light source passes through the end surface and through or from the end surface to the light responsive means.
Claim 3
Dependent Claim 11 words
Device according to claim 1, wherein the coating contains the ligand.
Claim 4
Dependent Claim 18 words
Device according to claim 2, wherein the coating contains the reaction product of the ligand and the reagent.
Claim 5
Dependent Claim 16 words
Device according to claim 1, wherein the coating contains a solid, transparent or translucent support matrix.
Claim 6
Dependent Claim 14 words
Device according to claim 4, wherein the support matrix is a non-woven paper web.
Claim 7
Dependent Claim 36 words
Device according to claim 4, wherein the light source is a light-emitting diode having a substantially flat transparent or translucent end surface through which the light passes, and wherein the coating is on the flat surface.
Claim 8
Dependent Claim 13 words
Device according to claim 6, wherein the light-emitting diode emits substantially monochromatic light.
Claim 9
Dependent Claim 39 words
Device according to claim 6, wherein the transmitted light from the coating has a longitudinal axis and the light responsive means is a photodetector having an optical axis that substantially coincides with the longitudinal axis of the transmitted light.

References Cited (Backward Citations)

US4050895A Cited
US4306877A Cited
US4321057A Cited
US4399099A Cited
US4368047A Cited
US4582809A Cited
US4447546A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-01-04 1991-07-06 1992-01-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-01-04 1995-07-06 1996-01-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-01-04 1999-07-06 2000-01-05 $7700.00 Window Closed / Lapsed

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