Patent US4716151A successfully refreshed from Google Patents.
US4716151A
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US
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Tripeptides and their use
Assignee: Rhone Poulenc Sante SA
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Filing: 1985-08-14
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Granted: 1987-12-29
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Expires: 2005-08-14
Abstract
Abstract Tripeptides composed of the amino acids glycine, leucine, and phenylalanine or tyrosine obtainable by fractionation of hydrolysis products of human casein or by direct synthesis can be used as immunostimulants.
Inventors
- 👤 Pierre Jolles
- 👤 Daniele Migliore-Samour
- 👤 Fabienne Parker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 04:14
CPC Classifications
C; C07; C07K; C07K5/00; C07K5/04; C07K5/08; C07K5/0802; C07K5/0804; C07K5/0806; A; A61; A61P; A61P37/00; A61P37/02; A61P37/04
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
38 words
A pharmaceutical composition having immunostimulant activity comprising an effective amount of a tripeptide selected from the group consisting of Gly-Leu-Phe, Gly-Leu-Tyr and Gly-Phe-Leu in combination with one or more diluents or adjuvants which are compatible and pharmaceutically acceptable.
Claim 2
Dependent Claim
38 words
A pharmaceutical composition having immunostimulant activity comprising an effective amount of a tripeptide selected from the group consisting of Gly-Leu-Phe, Gly-Leu-Tyr and Gly-Phe-Leu in combination with one or more diluents or adjuvants which are compatible and pharmaceutically acceptable.
Claim 3
Dependent Claim
24 words
A pharmaceutical composition according to claim 1 comprising the tripeptide Gly-Leu-Phe in combination with one or more diluents which are compatible and pharmaceutically acceptable.
Claim 4
Independent Claim
32 words
A method of stimulating the immune system in a subject which comprises administering to such subject an effective amount of a tripeptide selected from the group consisting of Gly-Leu-Phe, Gly-Leu-Tyr and Gly-Phe-Leu.
Claim 5
Independent Claim
32 words
A method of stimulating the immune system in a subject which comprises administering to such subject an effective amount of a tripeptide selected from the group consisting of Gly-Leu-Phe, Gly-Leu-Tyr and Gly-Phe-Leu.
Claim 6
Dependent Claim
20 words
A method according to claim 3 in which an effective amount of the tripeptide Gly-Leu-Phe is administered to said subject.
References Cited (Backward Citations)
FR1497536A
Cited
GB1158725A
Cited
GB1158727A
Cited
GB1158723A
Cited
GB1158726A
Cited
GB1158721A
Cited
GB1158724A
Cited
GB1158722A
Cited
CA1046441A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-12-28 | 1991-06-29 | 1991-12-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-12-28 | 1995-06-29 | 1995-12-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-12-28 | 1999-06-29 | 1999-12-29 | $7700.00 | Window Closed / Lapsed |