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US4716151A Expired / Lapsed US ⏱️ 0.0 years remaining

Tripeptides and their use

Assignee: Rhone Poulenc Sante SA
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Filing: 1985-08-14
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Granted: 1987-12-29
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Expires: 2005-08-14
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Abstract

Abstract Tripeptides composed of the amino acids glycine, leucine, and phenylalanine or tyrosine obtainable by fractionation of hydrolysis products of human casein or by direct synthesis can be used as immunostimulants.

Inventors

  • 👤 Pierre Jolles
  • 👤 Daniele Migliore-Samour
  • 👤 Fabienne Parker

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 03:59
CPC Classifications
C; C07; C07K; C07K5/00; C07K5/04; C07K5/08; C07K5/0802; C07K5/0804; C07K5/0806; A; A61; A61P; A61P37/00; A61P37/02; A61P37/04

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 38 words
A pharmaceutical composition having immunostimulant activity comprising an effective amount of a tripeptide selected from the group consisting of Gly-Leu-Phe, Gly-Leu-Tyr and Gly-Phe-Leu in combination with one or more diluents or adjuvants which are compatible and pharmaceutically acceptable.
Claim 2
Dependent Claim 38 words
A pharmaceutical composition having immunostimulant activity comprising an effective amount of a tripeptide selected from the group consisting of Gly-Leu-Phe, Gly-Leu-Tyr and Gly-Phe-Leu in combination with one or more diluents or adjuvants which are compatible and pharmaceutically acceptable.
Claim 3
Dependent Claim 24 words
A pharmaceutical composition according to claim 1 comprising the tripeptide Gly-Leu-Phe in combination with one or more diluents which are compatible and pharmaceutically acceptable.
Claim 4
Independent Claim 32 words
A method of stimulating the immune system in a subject which comprises administering to such subject an effective amount of a tripeptide selected from the group consisting of Gly-Leu-Phe, Gly-Leu-Tyr and Gly-Phe-Leu.
Claim 5
Independent Claim 32 words
A method of stimulating the immune system in a subject which comprises administering to such subject an effective amount of a tripeptide selected from the group consisting of Gly-Leu-Phe, Gly-Leu-Tyr and Gly-Phe-Leu.
Claim 6
Dependent Claim 20 words
A method according to claim 3 in which an effective amount of the tripeptide Gly-Leu-Phe is administered to said subject.

References Cited (Backward Citations)

FR1497536A Cited
GB1158725A Cited
GB1158727A Cited
GB1158723A Cited
GB1158726A Cited
GB1158721A Cited
GB1158724A Cited
GB1158722A Cited
CA1046441A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-12-28 1991-06-29 1991-12-29 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-12-28 1995-06-29 1995-12-29 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-12-28 1999-06-29 1999-12-29 $7700.00 Window Closed / Lapsed

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