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US4709015A Expired / Lapsed US ⏱️ 0.0 years remaining

Monoclonal antibody to human suppressor T cells

Assignee: Ortho Pharmaceutical Corp
•
Filing: 1984-08-09
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Granted: 1987-11-24
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Expires: 2004-08-09
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Abstract

Abstract Hybrid cell line for production of monoclonal antibody to an antigen found on normal human suppressor T cells. The hybrid is formed by fusing splenocytes from immunized CAF 1 mice with P3X63Ag8Ul myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.

Inventors

  • 👤 Patrick C. Kung
  • 👤 Gideon Goldstein

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-03 17:37
CPC Classifications
C; C07; C07K; C07K16/00; C07K16/18; C07K16/28; C07K16/2803; C07K16/2815; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/569; G01N33/56966; G01N33/56972; A; A61; A61K; A61K38/00; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/948

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 36 words
A monoclonai antibody produced by a hybridoma formed by fusion of cells from a mouse myeloma line and spleen cells from a mouse previously immunized with human thymocytes, which antibody reacts with human suppressor T cells.
Claim 2
Dependent Claim 36 words
A monoclonai antibody produced by a hybridoma formed by fusion of cells from a mouse myeloma line and spleen cells from a mouse previously immunized with human thymocytes, which antibody reacts with human suppressor T cells.
Claim 3
Dependent Claim 16 words
A monoclonai antibody which is produced from a hybridoma having the identifying characteristics of ATCC 8014.
Claim 4
Dependent Claim 16 words
A monoclonai antibody which is produced from a hybridoma having the identifying characteristics of ATCC 8014.
Claim 5
Dependent Claim 32 words
A monoclonai antibody having the identifying characteristics of the antibody secreted by ATCC 8014; said identifying characteristics comprising reacting with normal human suppressor T cells but not with normal human B cells.
Claim 6
Dependent Claim 32 words
A monoclonai antibody having the identifying characteristics of the antibody secreted by ATCC 8014; said identifying characteristics comprising reacting with normal human suppressor T cells but not with normal human B cells.

References Cited (Backward Citations)

US4196265A Cited
US4172124A Cited
US4349528A Cited
US4361550A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-11-23 1991-05-25 1991-11-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-11-23 1995-05-25 1995-11-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-11-23 1999-05-25 1999-11-24 $7700.00 Window Closed / Lapsed

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