Patent US4708802A successfully refreshed from Google Patents.
US4708802A
Expired / Lapsed
US
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Apparatus for hemodiafiltration
Assignee: B Braun Surgical AG
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Filing: 1986-08-18
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Granted: 1987-11-24
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Expires: 2006-08-18
Abstract
Abstract An apparatus for hemodiafiltration that maintains the blood concentration of the patient relatively constant. A pump is connected to a branch off the external flow path of the dialysator which pumps fluid to the circulation system of the patient to compensate for the patient's fluid loss through the hemodiafilter membrane. A suction pump which affects the transmembrane pressure across the hemodiafilter membrane is controlled to achieve the desired filtrate flow necessary to balance the return flow to the patient.
Inventors
- 👤 Dieter Rath
- 👤 Rolf Heitmeier
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 00:57
CPC Classifications
B; B01; B01D; B01D61/00; B01D61/14; B01D61/22; A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/34; A61M1/342; A61M1/3424; A61M1/3437; A61M1/3455; A61M1/3465; A61M1/3413
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
176 words
An apparatus for hemodiafiltration of a patient, comprising: a fluid source, a first volumetric pump connected to said fluid source for pumping fluid out of said source, a hemodiafilter containing a filter membrane disposed between a first chamber and a second chamber, one end of said first chamber being connected by a first conduit to said first volumetric pump for receiving said pumped fluid, one end of said second chamber being connected by a second conduit to the patient, a suction pump connected to the other end of said first chamber for removing fluid out of said first chamber, said suction pump being operable to maintain a constant transmembrane pressure across the filter membrane, and a second volumetric pump connected between said first conduit and said second conduit, said second volumetric pump being operable to deliver fluid from said first conduit to said second conduit, whereby fluid lost from the second chamber during hemodiafiltration is replaced in substantially equal quantity by fluid delivered from said first conduit to said second conduit by said second volumetric pump.
Claim 2
Independent Claim
176 words
An apparatus for hemodiafiltration of a patient, comprising: a fluid source, a first volumetric pump connected to said fluid source for pumping fluid out of said source, a hemodiafilter containing a filter membrane disposed between a first chamber and a second chamber, one end of said first chamber being connected by a first conduit to said first volumetric pump for receiving said pumped fluid, one end of said second chamber being connected by a second conduit to the patient, a suction pump connected to the other end of said first chamber for removing fluid out of said first chamber, said suction pump being operable to maintain a constant transmembrane pressure across the filter membrane, and a second volumetric pump connected between said first conduit and said second conduit, said second volumetric pump being operable to deliver fluid from said first conduit to said second conduit, whereby fluid lost from the second chamber during hemodiafiltration is replaced in substantially equal quantity by fluid delivered from said first conduit to said second conduit by said second volumetric pump.
Claim 3
Dependent Claim
26 words
An apparatus according to claim 1, further comprising a filter connected to said second volumetric pump for filtering the fluid delivered by said second volumetric pump.
Claim 4
Dependent Claim
37 words
An apparatus according to claim 1, further comprising air regulation means for regulating air quantity entering into said patient's circulatory system, said air regulation means being interconnected between said second volumetric pump and said patient's circulatory system.
Claim 5
Dependent Claim
39 words
An apparatus according to claim 1, further comprising measuring means for measuring a change in flow across said hemodiafilter, said measuring means being connected through a valve to said connection between said fluid source and said first volumetric pump.
Claim 6
Dependent Claim
53 words
An apparatus according to claim 4, wherein the outlet side of said suction pump is connected to the outlet side of said fluid source upstream of said measuring means via one or more valves, said one or more valves controllably diverting the outlet fluid flow from said suction pump to said fluid source.
Claim 7
Dependent Claim
84 words
An apparatus according to claim 1, further comprising: a first pressure meter interconnected between said first volumetric pump and said first chamber for measuring fluid pressure between said first volumetric pump and said first chamber, a second pressure meter interconnected between said suction pump and said first chamber for measuring fluid pressure between said suction pump and said first chamber, and a third pressure meter interconnected between said second chamber and said patient for measuring fluid pressure between said patient and said second chamber.
Claim 8
Dependent Claim
53 words
An apparatus according to claim 6, further comprising: control means operative on said suction pump for controlling pressure across said hemodiafilter, said control means including means for determining an actual transmembrane pressure of said hemodiafilter, and comparison means for comparing said actual transmembrane pressure to a predetermined desired value of a transmembrane pressure.
Claim 9
Dependent Claim
58 words
An apparatus according to claim 7, wherein said determination means calculates said acutal transmembrane pressure according to an algorithm, ##EQU2## where P 1 is the fluid pressure measured by said first pressue meter, P 2 is the fluid pressure measured by said second pressure meter, and P 3 is the fluid pressure measured by said third fluid meter.
Claim 10
Dependent Claim
12 words
An apparatus according to claim 7 wherein said control means is automatic.
Claim 11
Dependent Claim
29 words
An apparatus according to claim 1, further comprising a third pump interconnected between said second chamber and said patient for delivering blood from said patient to said second chamber.
Claim 12
Independent Claim
192 words
An apparatus for hemodiafiltration of a patient's blood comprising: a hemodiafilter having a filter membrane disposed between a first chamber and a second chamber, a first fluid conduit in communication with the first chamber, a first pump for delivering fluid through said first fluid conduit to said first chamber, a second pump in communication with said first chamber for removing fluid from said first chamber, said second pump being operable to maintain a constant pressure across the filter membrane of the hemodiafilter, a second fluid conduit in communication with the second chamber and in communication with the patient, a third fluid conduit in communication with the first fluid conduit at a location between the first pump and the first chamber and in communication with the second fluid conduit at a location between the second chamber and the patient, a third pump for delivering fluid through the third fluid conduit from the first fluid conduit to the second fluid conduit, whereby fluid lost from the second chamber during hemodiafiltration is replaced in substantially equal quantity by fluid delivered from the first fluid conduit to the second fluid conduit through the third fluid conduit.
Claim 13
Independent Claim
192 words
An apparatus for hemodiafiltration of a patient's blood comprising: a hemodiafilter having a filter membrane disposed between a first chamber and a second chamber, a first fluid conduit in communication with the first chamber, a first pump for delivering fluid through said first fluid conduit to said first chamber, a second pump in communication with said first chamber for removing fluid from said first chamber, said second pump being operable to maintain a constant pressure across the filter membrane of the hemodiafilter, a second fluid conduit in communication with the second chamber and in communication with the patient, a third fluid conduit in communication with the first fluid conduit at a location between the first pump and the first chamber and in communication with the second fluid conduit at a location between the second chamber and the patient, a third pump for delivering fluid through the third fluid conduit from the first fluid conduit to the second fluid conduit, whereby fluid lost from the second chamber during hemodiafiltration is replaced in substantially equal quantity by fluid delivered from the first fluid conduit to the second fluid conduit through the third fluid conduit.
Claim 14
Dependent Claim
20 words
An apparatus as in claim 11 further comprising: a sterile filter for filtering the fluid delivered through the third conduit.
Claim 15
Dependent Claim
35 words
An apparatus as in claim 11 further comprising: a buffer container in communication with the second conduit and the third conduit, the buffer container including an air detector for detecting air in the second conduit.
Claim 16
Dependent Claim
18 words
An apparatus as in claim 11 further comprising: monitoring means for monitoring the ultrafiltration rate of the hemodiafilter.
Claim 17
Dependent Claim
17 words
An apparatus as in claim 11 wherein said first pump and said second pump are volumetric pumps.
Claim 18
Dependent Claim
132 words
In a hemodiafiltration system of the type wherein blood from a patient is filtered through a hemodiafilter having a filter membrane disposed between a first chamber and a second chamber, a method of compensating for fluid loss from the second chamber during hemodiafiltration comprising the steps of: directing fluid from a fluid source to the first chamber through a first conduit, removing fluid from the first chamber at a rate such that the pressure across the filter membrane of the hemodiafilter remains constant, directing fluid from the second chamber to the patient through a second conduit, diverting fluid from the first conduit to the second conduit, whereby fluid lost from the second chamber during hemodiafiltration is replaced in substantially equal quantity by fluid diverted from the first conduit to the second conduit.
Claim 19
Dependent Claim
132 words
In a hemodiafiltration system of the type wherein blood from a patient is filtered through a hemodiafilter having a filter membrane disposed between a first chamber and a second chamber, a method of compensating for fluid loss from the second chamber during hemodiafiltration comprising the steps of: directing fluid from a fluid source to the first chamber through a first conduit, removing fluid from the first chamber at a rate such that the pressure across the filter membrane of the hemodiafilter remains constant, directing fluid from the second chamber to the patient through a second conduit, diverting fluid from the first conduit to the second conduit, whereby fluid lost from the second chamber during hemodiafiltration is replaced in substantially equal quantity by fluid diverted from the first conduit to the second conduit.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-11-23 | 1991-05-25 | 1991-11-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-11-23 | 1995-05-25 | 1995-11-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-11-23 | 1999-05-25 | 1999-11-24 | $7700.00 | Window Closed / Lapsed |