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US4703753A Expired / Lapsed US ⏱️ 0.0 years remaining

Radioactive aerosol inhalation apparatus

Assignee: CIS-US Inc A CORP OF
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Filing: 1986-11-10
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Granted: 1987-11-03
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Expires: 2006-11-10
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Abstract

Abstract A radioactive aerosol inhalation apparatus includes a lead-shielded container, having a lid or cover, and a disposable aerosol inhalation device for use in producing properly sized radioactive tagged particles. The disposable device includes a mouthpiece or air passageway communicating means attached to a wye connector for inhalation of the radioactive aerosol and exhalation to an entrapping filter. First and second conduits are respectively provided by flexible tubing from a nebulizer and to the filter. The first and second conduits are interconnected by a third conduit. A one-way valve is provided in the second conduit to allow a subject to exhale therethrough, while preventing inhalation therethrough. A further one-way valve is provided in the third conduit to allow fluid communication from the second conduit to the first conduit, while preventing fluid communication from the first conduit and the nebulizer to the second conduit. The optimum range of particle sizes is generated by producing an aerosol in the nebulizer which has an internal baffle. For ease of handling and to minimize radiation exposures, an entry is provided to add radioactive solution directly into the baffled nebulizer. A method involves using the apparatus to suply an aerosol containing radioactive tagged particles to a subject or patient for treatment and/or diagnosis.

Inventors

  • 👤 Maurice E. Bordoni
  • 👤 Ephraim Lieberman

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 19:25
CPC Classifications
A; A61; A61M; A61M15/00; A61M15/02; A61M16/00; A61M16/0057; A61M16/0063; A61M16/08; A61M16/0816; A61M16/0833; A61M16/0875

Claims Analysis

Total Claims: 55
Claim 1
Independent Claim 208 words
An aerosol inhalation apparatus for supplying an aerosol mist containing radioactive tagged particles to a subject, comprising a reusable radiation-shielding container having lid means, whereby the contents of the container are readily accessible, and a disposable radioactive aerosol inhalation device, the device including first and second conduit means in said container and passing therethrough, means for communicating with an air passageway of a subject connected to the first and second conduit means externally of said container, valve means for controlling exhalation from said second conduit means, a nebulizer within said container and connected to said first conduit means, means positioned at least in part within the container and in fluid communication with said nebulizer for allowing introduction of radioactive solution from outside said container into said nebulizer, means associated with said nebulizer for generating an aerosolized mist carrying radioactive tagged particles, means for introducing a mixture of air or oxygen and the mist into said first conduit means, third conduit means within said container interconnecting said first conduit means and said second conduit means, and entrapping filter means in said container and connected to said second conduit means for removing the aerosol exhaled, whereby the container may be reused and the device may be discarded after each use.
Claim 2
Dependent Claim 208 words
An aerosol inhalation apparatus for supplying an aerosol mist containing radioactive tagged particles to a subject, comprising a reusable radiation-shielding container having lid means, whereby the contents of the container are readily accessible, and a disposable radioactive aerosol inhalation device, the device including first and second conduit means in said container and passing therethrough, means for communicating with an air passageway of a subject connected to the first and second conduit means externally of said container, valve means for controlling exhalation from said second conduit means, a nebulizer within said container and connected to said first conduit means, means positioned at least in part within the container and in fluid communication with said nebulizer for allowing introduction of radioactive solution from outside said container into said nebulizer, means associated with said nebulizer for generating an aerosolized mist carrying radioactive tagged particles, means for introducing a mixture of air or oxygen and the mist into said first conduit means, third conduit means within said container interconnecting said first conduit means and said second conduit means, and entrapping filter means in said container and connected to said second conduit means for removing the aerosol exhaled, whereby the container may be reused and the device may be discarded after each use.
Claim 3
Dependent Claim 46 words
The aerosol inhalation apparatus according to claim 1, wherein said valve means is positioned within a portion of said second conduit means, said portion being within said container, and wherein said third conduit means is connected to said second conduit means downstream from said valve means.
Claim 4
Dependent Claim 17 words
The aerosol inhalation apparatus according to claim 2, wherein said valve means is a one-way valve means.
Claim 5
Dependent Claim 41 words
The aerosol inhalation apparatus according to claim 1, wherein said valve means comprises first one-way valve means positioned within a portion of said second conduit means and a second one-way valve means positioned with a portion of said third conduit means.
Claim 6
Dependent Claim 17 words
The aerosol inhalation apparatus according to claim 1, wherein said valve means is a one-way valve means.
Claim 7
Dependent Claim 54 words
The aerosol inhalation apparatus according to claim 1, wherein said means carried by said container for allowing introduction of a radioactive solution into said nebulizer comprises means in fluid communication with said nebulizer and with said first conduit means for permitting entry of atmospheric air into said nebulizer and into said first conduit means.
Claim 8
Dependent Claim 36 words
The aerosol inhalation apparatus according to claim 1, including means positioned within said container for removably fixing said device to said container, and means accessible from outside said container for unfixing said device from said container.
Claim 9
Dependent Claim 63 words
The aerosol inhalation apparatus according to claim 7, wherein said means accessible from outside said container for unfixing said device from said container includes a pivoted member, said pivoted member being pivoted about an axis intermediate its end portions, one of its end portions being positioned beneath said nebulizer, and an operator accessible to a user being coupled to its second end portion.
Claim 10
Dependent Claim 42 words
The aerosol inhalation apparatus according to claim 1, wherein said means for allowing introduction of a radioactive solution is an angulated port allowing a needle to extend into said container at an angle with respect to vertical to minimize exposure to radiation.
Claim 11
Dependent Claim 27 words
The aerosol inhalation apparatus according to claim 1, wherein said nebulizer includes a settling baffle to generate properly sized aerosol particles of less than substantially one micron.
Claim 12
Dependent Claim 43 words
The aerosol inhalation apparatus according to claim 10, wherein said nebulizer includes a diffuser and gas orifice, said settling baffle being positioned above said diffuser and said gas orifice for permitting aerosol particles larger than substantially one micron to remain in said nebulizer.
Claim 13
Dependent Claim 204 words
An aerosol inhalation apparatus for supplying an aerosol mist containing radioactive tagged particles to a subject, comprising a reusable generally cylindrical walled container having a closed bottom and an open top, radiation-shielding means within said wall and bottom of the container, the container having first, second and third openings formed therein, respectively, said openings being at the top portion of said container and being circumferentially spaced from each other, radiation-shielding lid means covering said container top portion, and a disposable pulmonary inhalation device including nebulizing means in said container, entrapping filter means within said container, means received in said first of said openings and including a conduit connected to said nebulizer means for introducing a radioactive liquid into said nebulizer means, means associated with said nebulizer means for generating an aerosolized mist having a plurality of radioactive tagged particles, inhalation conduit means received in said second of said openings and connected to said nebulizer means, and exhalation conduit means received in said third of said openings and connected to said filter means, and further conduit means within said container interconnecting said inhalation conduit means and said exhalation conduit means, whereby the container may be reused and the device may be discarded after each use.
Claim 14
Dependent Claim 204 words
An aerosol inhalation apparatus for supplying an aerosol mist containing radioactive tagged particles to a subject, comprising a reusable generally cylindrical walled container having a closed bottom and an open top, radiation-shielding means within said wall and bottom of the container, the container having first, second and third openings formed therein, respectively, said openings being at the top portion of said container and being circumferentially spaced from each other, radiation-shielding lid means covering said container top portion, and a disposable pulmonary inhalation device including nebulizing means in said container, entrapping filter means within said container, means received in said first of said openings and including a conduit connected to said nebulizer means for introducing a radioactive liquid into said nebulizer means, means associated with said nebulizer means for generating an aerosolized mist having a plurality of radioactive tagged particles, inhalation conduit means received in said second of said openings and connected to said nebulizer means, and exhalation conduit means received in said third of said openings and connected to said filter means, and further conduit means within said container interconnecting said inhalation conduit means and said exhalation conduit means, whereby the container may be reused and the device may be discarded after each use.
Claim 15
Dependent Claim 29 words
An aerosol inhalation apparatus according to claim 12, wherein said first, second and third openings are constituted by respective slots extending downwardly from a top edge of said container.
Claim 16
Dependent Claim 36 words
The aerosol inhalation apparatus according to claim 12, including means positioned within said container for removably fixing said device to said container, and means accessible from outside said container for unfixing said device from said container.
Claim 17
Dependent Claim 63 words
The aerosol inhalation apparatus according to claim 14, wherein said means accessible from outside said container for unfixing said device from said container includes a pivoted member, said pivoted member being pivoted about an axis intermediate its end portions, one of its end portions being positioned beneath said nebulizer, and an operator accessible to a user being coupled to its second end portion.
Claim 18
Dependent Claim 227 words
An aerosol inhalation apparatus for supplying an aerosol mist containing radioactive tagged particles and air and/or oxygen to a subject, comprising a reusable radiation-shielding container having lid means, whereby the contents of the container are readily accessible, and a disposable radioactive aerosol inhalation device, the device including first and second conduit means in said container and passing therethrough, means for communicating with an air passageway of a subject connected to the first and second conduit means externally of said container, valve means for controlling exhalation from said second conduit means, a nebulizer within said container and connected to said first conduit means, means positioned at least in part within the container and in fluid communication with said nebulizer for allowing introduction of radioactive solution from outside said container into said nebulizer, means in fluid communication with a source of air and/or oxygen, and with said nebulizer associated with said nebulizer for generating an aerosolized mist carrying airborne radioactive tagged particles, means for introducing a mixture of air and/or oxygen, and the mist into said first conduit means, third conduit means within said container interconnecting said first conduit means and said second conduit means, and entrapping filter means in said container and connected to said second conduit means for removing the aerosol exhaled, whereby the container may be reused and the device may be discarded after each use.
Claim 19
Dependent Claim 227 words
An aerosol inhalation apparatus for supplying an aerosol mist containing radioactive tagged particles and air and/or oxygen to a subject, comprising a reusable radiation-shielding container having lid means, whereby the contents of the container are readily accessible, and a disposable radioactive aerosol inhalation device, the device including first and second conduit means in said container and passing therethrough, means for communicating with an air passageway of a subject connected to the first and second conduit means externally of said container, valve means for controlling exhalation from said second conduit means, a nebulizer within said container and connected to said first conduit means, means positioned at least in part within the container and in fluid communication with said nebulizer for allowing introduction of radioactive solution from outside said container into said nebulizer, means in fluid communication with a source of air and/or oxygen, and with said nebulizer associated with said nebulizer for generating an aerosolized mist carrying airborne radioactive tagged particles, means for introducing a mixture of air and/or oxygen, and the mist into said first conduit means, third conduit means within said container interconnecting said first conduit means and said second conduit means, and entrapping filter means in said container and connected to said second conduit means for removing the aerosol exhaled, whereby the container may be reused and the device may be discarded after each use.
Claim 20
Dependent Claim 50 words
The aerosol inhalation apparatus according to claim 16, including further valve means positioned within said third conduit means for allowing fluid communication from said second conduit means to said first conduit means and for preventing fluid communication from said first conduit means and said nebulizer to said second conduit means.
Claim 21
Dependent Claim 57 words
The aerosol inhalation apparatus according to claim 16, wherein said means carried by said container for allowing introduction of a radioactive solution into said nebulizer comprises means in fluid communication wrth said nebulizer and with said first conduit means for permitting entry of atmospheric air or other ambient into said nebulizer and into said first conduit means.
Claim 22
Dependent Claim 45 words
The aerosol inhalation apparatus according to claim 18, wherein said nebulizer a diffuser, a settling baffle and gas orifice, said settling baffle being positioned above said diffuser and said gas orifice for permitting aersol particles larger than substantially one micron to remain in said nebulizer.
Claim 23
Dependent Claim 42 words
The aerosol inhalation apparatus according to claim 16, wherein said means fcr allowing introduction of a radioactive solution is an angulated port allowing a needle to extend into said container at an angle with respect to vertical to minimize exposure to radiation.
Claim 24
Dependent Claim 27 words
The aerosol inhalation apparatus according to claim 16, including a settling baffle in said nebulizer to generate properly sized aerosol particles of less than substantially one micron.
Claim 25
Dependent Claim 36 words
The aerosol inhalation apparatus according to claim 16, including means positioned within said container for removably fixing said device to said container, and means accessible from outside said container for unfixing said device from said container.
Claim 26
Dependent Claim 63 words
The aerosol inhalation apparatus according to claim 22, wherein said means accessible from outside said container for unfixing said device from said container includes a pivoted member, said pivoted member being pivoted about an axis intermediate its end portions, one of its end portions being positioned beneath said nebulizer, and an operator accessible to a user being coupled to its second end portion.
Claim 27
Dependent Claim 225 words
An aerosol inhalation apparatus for supplying an aerosol mist containing radioactive charged particles and air and/or oxygen to a subject, comprising a reusable generally cylindrical walled container having a closed bottom and an open top, lead radiation-shielding means within said wall and said bottom of the container, the container having first, second and third openings formed therein, respectively, said openings being at the top portion of said container and being circumferentially spaced from each other, lead radiation-shielding lid means covering said container top portion, a disposable pulmonary inhalation device including nebulizing means in said container, entrapping filter means within said container, means received in said first of said openings and including a conduit connected to said nebulizer means for introducing a radioactive liquid into said nebulizer means, means associated with nebulizer means for generating an aerosolized mist having a plurality of radioactive tagged particles, inhalation conduit means received in said second of said openings and connected to a source of air and/or oxygen and to said nebulizer means for receiving a mixture of air and/or oxygen and the mist, exhalation conduit means received in said third and of said openings and connected to said filter means, and further conduit means interconnecting said inhalation conduit means and said exhalation conduit means, whereby the container may be reused and the device may be discarded after each use.
Claim 28
Dependent Claim 225 words
An aerosol inhalation apparatus for supplying an aerosol mist containing radioactive charged particles and air and/or oxygen to a subject, comprising a reusable generally cylindrical walled container having a closed bottom and an open top, lead radiation-shielding means within said wall and said bottom of the container, the container having first, second and third openings formed therein, respectively, said openings being at the top portion of said container and being circumferentially spaced from each other, lead radiation-shielding lid means covering said container top portion, a disposable pulmonary inhalation device including nebulizing means in said container, entrapping filter means within said container, means received in said first of said openings and including a conduit connected to said nebulizer means for introducing a radioactive liquid into said nebulizer means, means associated with nebulizer means for generating an aerosolized mist having a plurality of radioactive tagged particles, inhalation conduit means received in said second of said openings and connected to a source of air and/or oxygen and to said nebulizer means for receiving a mixture of air and/or oxygen and the mist, exhalation conduit means received in said third and of said openings and connected to said filter means, and further conduit means interconnecting said inhalation conduit means and said exhalation conduit means, whereby the container may be reused and the device may be discarded after each use.
Claim 29
Dependent Claim 29 words
An aerosol inhalation apparatus according to claim 24, wherein said first, second and third openings are constituted by respective slots extending downwardly from a top edge of said container.
Claim 30
Dependent Claim 36 words
The aerosol inhalation apparatus according to claim 24, including means positioned within said container for removably fixing said device to said container, and means accessible from outside said container for unfixing said device from said container.
Claim 31
Dependent Claim 63 words
The aerosol inhalation apparatus according to claim 26, wherein said means accessible from outside said container for unfixing said device from said container includes a pivoted member, said pivoted member being pivoted about an axis intermediate its end portions, one of its end portions being positioned beneath said nebulizer, and an operator accessible to a user being coupled to its second end portion.
Claim 32
Dependent Claim 115 words
An aerosol inhalation device for supplying an aerosol mist to a subject, the device comprising first and second conduit means, means for communicating with an air passageway of a subject connected to the first and second conduit means, valve means for controlling exhalation from said second conduit means, a nebulizer coupled to said first conduit means, means in fluid communication with said nebulizer for allowing introduction of liquid into said nebulizer, means associated with said nebulizer for generating an aerosolized mist carrying airborne particles, third conduit means interconnecting said first conduit means and said second conduit means, and means for introducing a mixture of air and/or oxygen, and the mist into said first conduit means.
Claim 33
Dependent Claim 115 words
An aerosol inhalation device for supplying an aerosol mist to a subject, the device comprising first and second conduit means, means for communicating with an air passageway of a subject connected to the first and second conduit means, valve means for controlling exhalation from said second conduit means, a nebulizer coupled to said first conduit means, means in fluid communication with said nebulizer for allowing introduction of liquid into said nebulizer, means associated with said nebulizer for generating an aerosolized mist carrying airborne particles, third conduit means interconnecting said first conduit means and said second conduit means, and means for introducing a mixture of air and/or oxygen, and the mist into said first conduit means.
Claim 34
Dependent Claim 39 words
The aerosol inhalation device according to claim 28, wherein said valve means is positioned within said second conduit means, and wherein said third conduit means is in fluid communication with said second conduit means downstream from said valve means.
Claim 35
Dependent Claim 17 words
The aerosol inhalation device according to claim 29, wherein said valve means is a one-way valve means.
Claim 36
Dependent Claim 38 words
The aerosol inhalation device according to claim 28, wherein said valve means comprises first one-way valve means positioned within a portion of said second conduit means and a second one-way valve means positioned within said third conduit means.
Claim 37
Dependent Claim 49 words
The aerosol inhalation device according to claim 28, wherein said means for allowing introduction of a liquid into said nebulizer comprises means in fluid communication with said nebulizer and with said first conduit means for permitting entry of atmospheric air into said nebulizer and into said first conduit means.
Claim 38
Dependent Claim 26 words
The aerosol inhalation device according to claim 32, including a settling baffle within said nebulizer, said baffle having an inner surface defined by an arcuate dome.
Claim 39
Dependent Claim 24 words
The aerosol inhalation device according to claim 32, including throttle means disposed in fluid communication path between said nebulizer and said first conduit means.
Claim 40
Dependent Claim 15 words
The inhalation device according to claim 34, wherein said throttle means is changeable or adjustable.
Claim 41
Dependent Claim 25 words
The aerosol inhalation device according to claim 28, including a settling baffle in said nebulizer to generate aerosol particles of less than substantially one micron.
Claim 42
Dependent Claim 43 words
The aerosol inhalation device according to claim 36, wherein said nebulizer includes a diffuser and gas orifice, said settling baffle being positioned above said diffuser and said gas orifice for permitting aerosol particles larger than substantially one micron to remain in said nebulizer.
Claim 43
Dependent Claim 66 words
In an aerosol inhalation apparatus for supplying an aerosol mist containing radioactive tagged particles to a subject and including a disposable aerosol inhalation device and radiation-shielding container means, at least a portion of the device being removably fixed within said container means, an improvement comprising means at least partially positioned within said container and accessible from outside said container for unfixing, the device from said container.
Claim 44
Dependent Claim 66 words
In an aerosol inhalation apparatus for supplying an aerosol mist containing radioactive tagged particles to a subject and including a disposable aerosol inhalation device and radiation-shielding container means, at least a portion of the device being removably fixed within said container means, an improvement comprising means at least partially positioned within said container and accessible from outside said container for unfixing, the device from said container.
Claim 45
Dependent Claim 67 words
An improved aerosol inhalation apparatus according to claim 38, wherein said means positioned within said container and accessible from outside said container includes a pivoted member pivoted about an axis intermediate its end portions, one of said end positions being positioned beneath a portion of said device to unfix said device from said container, an operator accessible to a user being coupled to its other end portion.
Claim 46
Dependent Claim 123 words
An aerosol inhalation device for supplying an aerosol mist to a subject, the device comprising first and second conduit means, means for communicating with an air passageway of a subject connected the first and second conduit means, valve means for controlling exhalation from said second conduit means, throttle means coupled to said first conduit means, a nebulizer coupled to said first conduit means via said throttle means, means in fluid communication with said nebulizer for allowing introduction of liquid into said nebulizer, means associated with said nebulizer for generating an aerosolized mist, third conduit means interconnecting said first conduit means and said second conduit means, and means for introducing a mixture of air and/or oxygen, and the mist into said first conduit means.
Claim 47
Dependent Claim 123 words
An aerosol inhalation device for supplying an aerosol mist to a subject, the device comprising first and second conduit means, means for communicating with an air passageway of a subject connected the first and second conduit means, valve means for controlling exhalation from said second conduit means, throttle means coupled to said first conduit means, a nebulizer coupled to said first conduit means via said throttle means, means in fluid communication with said nebulizer for allowing introduction of liquid into said nebulizer, means associated with said nebulizer for generating an aerosolized mist, third conduit means interconnecting said first conduit means and said second conduit means, and means for introducing a mixture of air and/or oxygen, and the mist into said first conduit means.
Claim 48
Dependent Claim 39 words
The aerosol inhalation device according to claim 40, wherein said valve means is positioned within said second conduit means, and wherein said third conduit means is in fluid communication with said second conduit means downstream from said valve means.
Claim 49
Dependent Claim 17 words
The aerosol inhalation device according to claim 41, wherein said valve means is a one-way valve means.
Claim 50
Dependent Claim 38 words
The aerosol inhalation device according to claim 40, wherein said valve means comprises first one-way valve means positioned within a portion of said second conduit means and a second one-way valve means positioned within said third conduit means.
Claim 51
Dependent Claim 111 words
An aerosol inhalation device for supplying an aerosol mist to a subject, the device comprising first and second conduit means, means for communicating with an air passageway of a subject connected to the first and second conduit means, valve means for controlling exhalation from said second conduit means, throttle means coupled to said first conduit means, a nebulizer coupled to said first conduit means via said throttle means, means in fluid communication with said nebulizer for allowing introduction of liquid into said nebulizer, means associated with said nebulizer for generating an aerosolized mist, and means for introducing a mixture of air and/or oxygen, and the mist into said first conduit means.
Claim 52
Dependent Claim 111 words
An aerosol inhalation device for supplying an aerosol mist to a subject, the device comprising first and second conduit means, means for communicating with an air passageway of a subject connected to the first and second conduit means, valve means for controlling exhalation from said second conduit means, throttle means coupled to said first conduit means, a nebulizer coupled to said first conduit means via said throttle means, means in fluid communication with said nebulizer for allowing introduction of liquid into said nebulizer, means associated with said nebulizer for generating an aerosolized mist, and means for introducing a mixture of air and/or oxygen, and the mist into said first conduit means.
Claim 53
Dependent Claim 19 words
The aerosol inhalation device according to claim 44, wherein said valve means is positioned within said second conduit means.
Claim 54
Dependent Claim 17 words
The aerosol inhalation device according to claim 45, wherein said valve means is a one-way valve means.
Claim 55
Dependent Claim 49 words
The aerosol inhalation device according to claim 44, including third conduit means interconnecting said first and second conduit means, wherein said valve means comprises first one-way valve means positioned within a portion of said second conduit means and a second one-way valve means positioned within said third conduit means.

References Cited (Backward Citations)

US1839193A Cited
US3695254A Cited
US3881463A Cited
US3915386A Cited
US4116387A Cited
US4333450A Cited
US4251033A Cited
US4402315A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-11-02 1991-05-04 1991-11-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-11-02 1995-05-04 1995-11-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-11-02 1999-05-04 1999-11-03 $7700.00 Window Closed / Lapsed

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