Patent US4702918A successfully refreshed from Google Patents.
US4702918A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical preparations and a method of manufacturing them
Assignee: Nippon Shinyaku Co Ltd
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Filing: 1985-08-02
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Granted: 1987-10-27
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Expires: 2005-08-02
Abstract
Abstract A sustained-release composition, which comprises (a) a substance which forms a gel in water, (b) a fat and/or oil which is solid at room temperature and (c) a pharmaceutical, said composition having a specific gravity of not more than about 1.
Inventors
- 👤 Koichi Ushimaru
- 👤 Koichi Nakamichi
- 👤 Hitoshi Saito
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 23:29
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0065; A61K9/48; A61K9/4841; A61K9/4858; A61K9/4866
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
137 words
A sustained-release composition in capsule form having a specific gravity of not more than about 1, said capsules containing a mixture of (a) from about 10 to about 90% by weight of a cellulose derivative or a starch derivative which forms a gel in water and (b) from about 90 to 10% by weight of a higher fatty acid glyceride or higher alcohol or a mixture thereof which is solid at room temperature, both based on the weight of (a) and (b), and (c) from 0.01 to about 85% by weight based on the weight of (a), (b) and (c) of a pharmaceutical, said capsules having been prepared by filling capsules with said mixture of (a), (b) and (c), heating said capsules to a temperature above the melting point of (b) and cooling and solidifying said mixture.
Claim 2
Dependent Claim
137 words
A sustained-release composition in capsule form having a specific gravity of not more than about 1, said capsules containing a mixture of (a) from about 10 to about 90% by weight of a cellulose derivative or a starch derivative which forms a gel in water and (b) from about 90 to 10% by weight of a higher fatty acid glyceride or higher alcohol or a mixture thereof which is solid at room temperature, both based on the weight of (a) and (b), and (c) from 0.01 to about 85% by weight based on the weight of (a), (b) and (c) of a pharmaceutical, said capsules having been prepared by filling capsules with said mixture of (a), (b) and (c), heating said capsules to a temperature above the melting point of (b) and cooling and solidifying said mixture.
Claim 3
Dependent Claim
18 words
The composition of claim 1, wherein (a) is hydroxypropylecllulose, methylcellose, carboxymethylcellulose, hydroxypropylmethylcellulose or alpha-starch or a mixture thereof.
Claim 4
Dependent Claim
29 words
The composition of claim 1, wherein (b) is stearic acid, palmitic acid, hardened castor oil, beeswax, stearyl alcohol or ethyl alcohol or a mixture of two or more thereof.
Claim 5
Dependent Claim
48 words
A method of making the sustained-release composition according to claim 1, in capsule form, wherein a mixture of (a), (b) and (c) is formed and filled into capsules, the capsules are heated to a temperature above the melting point of (b), whereafter the mixture is cooled and solidified.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-10-26 | 1991-04-27 | 1991-10-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-10-26 | 1995-04-27 | 1995-10-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-10-26 | 1999-04-27 | 1999-10-27 | $7700.00 | Window Closed / Lapsed |