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US4699787A
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Nitrogen-containing polysaccharide
Assignee: Kureha Corp
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Filing: 1984-03-06
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Granted: 1987-10-13
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Expires: 2004-03-06
Abstract
Abstract A method of restoring the immune response of a patient having a lowered immune response level is provided, in which the patient is given an effective amount of certain nitrogen-containing polysaccharides derived from Coriolus versicolor (Fr.) Quel, where the polymer units having a molecular weight of below about 5,000 have been removed therefrom.
Inventors
- 👤 Saburo Ueno
- 👤 Chikao Yoshikumi
- 👤 Yoshio Omura
- 👤 Takayoshi Fujii
- 👤 Toshihiko Wada
- 👤 Eiichi Takahashi
- 👤 Fumio Hirose
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 15:25
CPC Classifications
A; A61; A61K; A61K36/00; A61K36/06; A61K36/07; A61K36/074; A61P; A61P35/00; C; C12; C12P; C12P21/00; C12P21/005
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
113 words
A method of restoring the immune response of a patient having a lowered immune response level which comprises administering to said patient an effective amount of a nitrogen-containing polysaccharide substantially free of units having a molecular weight below about 5,000, said nitrogen-containing polysaccharide being a product produced by extracting Coriolus versicolor (Fr.) Quel. with an aqueous alkaline solution having a concentration within the range of from 0.01 to 2.0N at a temperature of from 50° C. to 100° C. for 20 to 600 minutes, neutralizing the resultant extract, and subjecting the thus neutralized extract to ultrafiltration and/or reverse osmosis to remove substantially all polymer units having a molecular weight below about 5000 therefrom.
Claim 2
Independent Claim
113 words
A method of restoring the immune response of a patient having a lowered immune response level which comprises administering to said patient an effective amount of a nitrogen-containing polysaccharide substantially free of units having a molecular weight below about 5,000, said nitrogen-containing polysaccharide being a product produced by extracting Coriolus versicolor (Fr.) Quel. with an aqueous alkaline solution having a concentration within the range of from 0.01 to 2.0N at a temperature of from 50° C. to 100° C. for 20 to 600 minutes, neutralizing the resultant extract, and subjecting the thus neutralized extract to ultrafiltration and/or reverse osmosis to remove substantially all polymer units having a molecular weight below about 5000 therefrom.
Claim 3
Dependent Claim
31 words
The method of restoring the immune response of a patient according to claim 1 wherein said lowered immune response level is caused by affliction with cancer, but without treating the cancer.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-10-12 | 1991-04-13 | 1991-10-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-10-12 | 1995-04-13 | 1995-10-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-10-12 | 1999-04-13 | 1999-10-13 | $7700.00 | Window Closed / Lapsed |