US4698326A
Expired / Lapsed
US
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Composition and method for osseous repair
Assignee: 3M Co
•
Filing: 1985-12-20
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Granted: 1987-10-06
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Expires: 2005-12-20
Abstract
Abstract A composition and method for the repair of an osseous defect comprising introducing into said defect a phosphophoryn calcium salt, preferably in combination with a matrix material such as type I collagen.
Inventors
- 👤 John J. Sauk
- 👤 Craig L. Van Kampen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 23:45
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/14; A61L27/22; A61L27/227; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/39; A61L24/00; A61L24/04; A61L24/043; A61L24/10; A61L24/102; A61L2430/00; A61L2430/38
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
58 words
A composition for osseous repair which is prepared by a process comprising mixing a phosphophoryn calcium salt and type I collagen in a ratio of the phosphophoryn calcium salt to the type I collagen of about 3.0-0.1:1 to yield a solid composition which is effective to promote new bone formation upon introduction of the composition into osseous defects.
Claim 2
Dependent Claim
58 words
A composition for osseous repair which is prepared by a process comprising mixing a phosphophoryn calcium salt and type I collagen in a ratio of the phosphophoryn calcium salt to the type I collagen of about 3.0-0.1:1 to yield a solid composition which is effective to promote new bone formation upon introduction of the composition into osseous defects.
Claim 3
Dependent Claim
14 words
The composition of claim 1 wherein the mixture contains a dentinal phosphophoryn calcium salt.
Claim 4
Dependent Claim
23 words
The composition of claim 1 wherein the weight ratio of the dentinal phosphophoryn calcium salt to the type I collagen is about 1:1.
Claim 5
Dependent Claim
29 words
The composition of claim 1 wherein a mixture of the phosphophoryn calcium salt and the type I collagen in water is prepared and the water is removed in vacuo.
Claim 6
Dependent Claim
12 words
The composition of claim 2 wherein the water is removed by lyophilization.
Claim 7
Independent Claim
30 words
A method for the repair of an osseous defect comprising introducing into said defect a composition comprising an amount of a phosphophoryn calcium salt effective to promote new bone formation.
Claim 8
Independent Claim
30 words
A method for the repair of an osseous defect comprising introducing into said defect a composition comprising an amount of a phosphophoryn calcium salt effective to promote new bone formation.
Claim 9
Independent Claim
34 words
A method for the repair of an osseous defect comprising introducing into said defect a composition comprising a mixture of a phosphophoryn calcium salt and type I collagen effective to promote new bone formation.
Claim 10
Independent Claim
34 words
A method for the repair of an osseous defect comprising introducing into said defect a composition comprising a mixture of a phosphophoryn calcium salt and type I collagen effective to promote new bone formation.
Claim 11
Dependent Claim
57 words
An osseous repair implant which is prepared by a process comprising introducing an amount of a solid composition containing an amount of a phosphophoryn calcium salt effective to promote new bone formation in an osseous defect having an exposed surface so that said composition presents a surface opposing and conformed to the exposed surface of said defect.
Claim 12
Dependent Claim
57 words
An osseous repair implant which is prepared by a process comprising introducing an amount of a solid composition containing an amount of a phosphophoryn calcium salt effective to promote new bone formation in an osseous defect having an exposed surface so that said composition presents a surface opposing and conformed to the exposed surface of said defect.
Claim 13
Dependent Claim
11 words
The composition of claim 8 wherein said composition fills said defect.
Claim 14
Dependent Claim
14 words
The composition of claim 8 wherein the composition contains a dentinal phosphophoryn calcium salt.
Claim 15
Dependent Claim
12 words
The composition of claim 10 wherein the composition contains type I collagen.
Claim 16
Dependent Claim
22 words
The composition of claim 11 wherein the weight ratio of the phosphophoryn calcium salt to the type I collagen is about 3.0-0.1:1.
Claim 17
Dependent Claim
22 words
The composition of claim 12 wherein the weight ratio of the phosphophoryn calcium salt to the type I collagen is about 1:1.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-10-05 | 1991-04-06 | 1991-10-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-10-05 | 1995-04-06 | 1995-10-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-10-05 | 1999-04-06 | 1999-10-06 | $7700.00 | Window Closed / Lapsed |