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US4694072A
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Peptides comprising an immunogenic site of poliovirus and DNAS containing nucleotide sequences coding for these peptides
Assignee: Institut Pasteur
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Filing: 1983-11-30
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Granted: 1987-09-15
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Expires: 2003-11-30
Abstract
Abstract PCT No. PCT/FR83/00241 Sec. 371 Date Jul. 27, 1984 Sec. 102(e) Date Jul. 27, 1984 PCT Filed Nov. 30, 1983.The invention relates to a DNA fragment containing at the most 315 parts of nucleotides coding for a peptide which can be recognized by antibodies acting both against the "C" and "D" particles of the same poliovirus and against the VP-1 structural polypeptide of the capsid of this poliovirus. This peptide contains in particular the following sequence: Asp Asn Pro Ala Ser Thr Thr Asn Lys Asp Lys Leu.
Inventors
- 👤 Marc Girard
- 👤 Sylvie van der Werf
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 16:06
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/005; A; A61; A61P; A61P31/00; A61P31/12; C12; C12Q; C12Q1/00; C12Q1/70; C12Q1/701; A61K; A61K39/00; C12N; C12N2770/00; C12N2770/00011; C12N2770/32011; C12N2770/32611; C12N2770/32622; C12N2770/32634; Y; Y02; Y02A; Y02A50/00; Y02A50/30
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
111 words
Polypeptide constituted by the sequence: Ser Arg Asp Ala Leu Pro Asn Thr GLu Ala Ser Gly Pro Thr His Ser Lys Glu Ile Pro Ala Leu Thr Ala Val Glu Thr Gly Ala Thr Asn Pro Leu Val Pro Ser Asp Thr Val Gln Thr Arg His Val Val Gin His Arg Ser Arg Ser Glu Ser Ser Ile Glu Ser Phe Phe Ala Arg Gly Ala Cys Val Thr Ile Met Thr Val Asp Asn Pro Ala Ser Thr Thr Asn Lys Asp Lys Leu Phe Ala Val Trp Lys Ile Thr Tyr Lys Asp Thr Val Gln Leu Arg Arg Lys Leu Glu Phe Phe Thr Tyr Ser.
Claim 2
Dependent Claim
111 words
Polypeptide constituted by the sequence: Ser Arg Asp Ala Leu Pro Asn Thr GLu Ala Ser Gly Pro Thr His Ser Lys Glu Ile Pro Ala Leu Thr Ala Val Glu Thr Gly Ala Thr Asn Pro Leu Val Pro Ser Asp Thr Val Gln Thr Arg His Val Val Gin His Arg Ser Arg Ser Glu Ser Ser Ile Glu Ser Phe Phe Ala Arg Gly Ala Cys Val Thr Ile Met Thr Val Asp Asn Pro Ala Ser Thr Thr Asn Lys Asp Lys Leu Phe Ala Val Trp Lys Ile Thr Tyr Lys Asp Thr Val Gln Leu Arg Arg Lys Leu Glu Phe Phe Thr Tyr Ser.
Claim 3
Dependent Claim
54 words
The polypeptide of claim 1 the sequence: ______________________________________
His Val Val Gln His
Arg Ser Arg Ser Glu Ser Ser Ile Glu Ser
70
Phe Phe Ala Arg Gly Ala Cys Val Thr Ile
80
Met Thr Val Asp Asn Pro Ala Ser Thr Thr
90
Asn Lys Asp Lys Leu Phe
100
______________________________________
Claim 4
Dependent Claim
60 words
The polypeptide of claim 1 the sequence: ______________________________________
His Val Val Gln His
Arg Ser Arg Ser Glu Ser Ser Ile Glu Ser
70
Phe Phe Ala Arg Gly Ala Cys Val Thr Ile
80
Met Thr Val Asp Asn Pro Ala Ser Thr Thr
90
Asn Lys Asp Lys Leu Phe Ala Val Trp Lys
100
Ile
110
______________________________________
Claim 5
Dependent Claim
18 words
The polypeptide of claim 1 sequence: Asp Asn Pro Ala Ser Thr Thr Asn Lys Asp Lys Leu.
Claim 6
Dependent Claim
40 words
Water-soluble oligomer, containing from 2 to 10 monomer units, wherein the monomeric unit consists of a polypeptide having a sequence Asp Asn Pro Ala Ser Thr Thr Asn Lys Asp Lys Leu, said monomeric unit containing less than 20 aminoacids.
Claim 7
Dependent Claim
40 words
Water-soluble oligomer, containing from 2 to 10 monomer units, wherein the monomeric unit consists of a polypeptide having a sequence Asp Asn Pro Ala Ser Thr Thr Asn Lys Asp Lys Leu, said monomeric unit containing less than 20 aminoacids.
References Cited (Backward Citations)
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| 3.5 Years (Year 4) | 1990-09-14 | 1991-03-16 | 1991-09-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-09-14 | 1995-03-16 | 1995-09-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-09-14 | 1999-03-16 | 1999-09-15 | $7700.00 | Window Closed / Lapsed |