Procedure for photometric measurement of liquids in reaction vessels, and reaction vessel

Claim 2

A procedure for photometric measurement of liquids contained in reaction vessels in an automatic analyzer by utilizing a radiation flow along a path substantially perpendicular to a row of the reaction vessels, comprising: filling each reaction vessel in a row of vessels with liquid to be photometrically measured, each vessel being contiguous with an adjacent vessel and separated by a common wall so as to form a unitary cuvette; continuously moving the cuvette and contained liquid past a radiation flux source and a photometric detector measuring unit by engaging a mating member provided at one end of the cuvette with an engagement member in an automatic analyzer capable of moving the cuvette continuously in a longitudinal direction, wherein the reaction vessels are each in continuous movement relative to the photometric detector; and passing the radiation flow continuously through side walls of each reaction vessel and the liquid contained therein and continuously photometrically measuring the contained liquid and also measuring the distance between adjacent reaction vessels, and determining a mean value of the radiation response from signals generated by the photometric measuring unit, so that the mean value of the radiation response is measured over substantially the entire length of each reaction vessel of the cuvette.

Claim 3

A photometric measurement procedure according to claim 1, wherein any portion of the photometric measurement signals deviating substantially from an average signal level is disregarded for determining a mean value of the radiation response from each contained liquid.

Claim 4

A photometric measuring procedure according to claim 1, wherein luminescence from the liquid in each said reaction vessel of the cuvette is additionally measured through a convex shaped lens which lens comprises a bottom of each reaction vessel.

Claim 5

A row of reaction vessels for continuous photometric measurement of liquids, each reaction vessel in the row being contiguous with an adjacent vessel and separated by a common wall so as to form a unitary cuvette, wherein opposite sides of each reaction vessel are flat for receiving a continuous radiation flow from a radiation source, and the bottom of each reaction vessel of the cuvette comprises a lens, said lens having a convex shaped radius on its lower side for directing luminescent radiation from a liquid in the vessel; and at least one end of the cuvette being provided with a mating member adapted for being engaged with an engagement member for use in moving the cuvette continuously past a radiation source by means of the engagement member.

Claim 6

A row of reaction vessels for continuous photometric measurement of liquids, each reaction vessel in the row being contiguous with an adjacent vessel and separated by a common wall so as to form a unitary cuvette, wherein opposite sides of each reaction vessel are flat for receiving a continuous radiation flow from a radiation source, and the bottom of each reaction vessel of the cuvette comprises a lens, said lens having a convex shaped radius on its lower side for directing luminescent radiation from a liquid in the vessel; and at least one end of the cuvette being provided with a mating member adapted for being engaged with an engagement member for use in moving the cuvette continuously past a radiation source by means of the engagement member.

Claim 7

A row of reaction vessels according to claim 4, wherein the mating member comprises a projection having a bevelled face which is bevelled upwardly towards the cuvette whereby an engagement member can engage the projection and move the row of reaction vessels continuously past the radiation source.

Claim 8

A row of reaction vessels according to claim 4, wherein the mating member comprises a piece of magnetic material for contact by a magnetic engagement member for moving the row of reaction vessels continuously past the radiation source.

Claim 9

A procedure for photometric measurement of liquids contained in adjacent reaction vessels in an automatic analyzer by utilizing a radiation flow along a path substantially perpendicular to a row of the reaction vessels, comprising: (a) filling each reaction vessel in the row of vessels with a liquid to be photometrically measured, each reaction vessel being contiguous with an adjacent vessel and separated by a common wall so as to form a unitary cuvette; (b) continuously moving the cuvette and liquid contained in the vessels past a radiation flux source and a photometric detector measuring unit by engaging a mating member provided at one end of the cuvette with an engagement member in an automatic analyzer capable of moving the cuvette continuously in a longitudinal direction, wherein the reaction vessels are each in continuous movement relative to the photometric detector, and passing the radiation flow continuously through side walls of the reaction vessels and liquid contained therein and continuously measuring the radiation response from signals received by the photometric detector measuring unit; (c) continuously measuring the distance between adjacent reaction vessels and determining a mean value of the radiation response for each liquid sample in each reaction vessel over a length of the vessel by disregarding any portion of the measurement signal deviating substantially from an average signal level for determining the mean value of the radiation response from the contained liquid, so that the radiation is measured over substantially the entire length of each vessel; and (d) continuously measuring luminescence from the liquid sample in each said reaction vessel through a lens located at a bottom end of each reaction vessel.

Claim 10

A procedure for photometric measurement of liquids contained in adjacent reaction vessels in an automatic analyzer by utilizing a radiation flow along a path substantially perpendicular to a row of the reaction vessels, comprising: (a) filling each reaction vessel in the row of vessels with a liquid to be photometrically measured, each reaction vessel being contiguous with an adjacent vessel and separated by a common wall so as to form a unitary cuvette; (b) continuously moving the cuvette and liquid contained in the vessels past a radiation flux source and a photometric detector measuring unit by engaging a mating member provided at one end of the cuvette with an engagement member in an automatic analyzer capable of moving the cuvette continuously in a longitudinal direction, wherein the reaction vessels are each in continuous movement relative to the photometric detector, and passing the radiation flow continuously through side walls of the reaction vessels and liquid contained therein and continuously measuring the radiation response from signals received by the photometric detector measuring unit; (c) continuously measuring the distance between adjacent reaction vessels and determining a mean value of the radiation response for each liquid sample in each reaction vessel over a length of the vessel by disregarding any portion of the measurement signal deviating substantially from an average signal level for determining the mean value of the radiation response from the contained liquid, so that the radiation is measured over substantially the entire length of each vessel; and (d) continuously measuring luminescence from the liquid sample in each said reaction vessel through a lens located at a bottom end of each reaction vessel.

Claim 11

A row of reaction vessels for making continuous photometric measurements of liquids, each reaction vessel in the row being contiguous with an adjacent vessel and separated by a common wall so as to form a unitary cuvette, wherein opposite sides of each reaction vessel are flat for receiving a continuous radiation flow from a radiation source, and the bottom of each reaction vessel of the cuvette comprises a lens for focusing luminescent radiation from liquid in the vessel, said lens having a convex shaped radius on its lower side for directing luminescent radiation from the liquid in the vessel; and wherein at one end of said row of vessels there is provided a mating member having a bevelled face bevelled upwardly towards the the cuvette and for engaging and moving the vessel row continuously past the radiation source by an engagement member.

Claim 12

A row of reaction vessels for making continuous photometric measurements of liquids, each reaction vessel in the row being contiguous with an adjacent vessel and separated by a common wall so as to form a unitary cuvette, wherein opposite sides of each reaction vessel are flat for receiving a continuous radiation flow from a radiation source, and the bottom of each reaction vessel of the cuvette comprises a lens for focusing luminescent radiation from liquid in the vessel, said lens having a convex shaped radius on its lower side for directing luminescent radiation from the liquid in the vessel; and wherein at one end of said row of vessels there is provided a mating member having a bevelled face bevelled upwardly towards the the cuvette and for engaging and moving the vessel row continuously past the radiation source by an engagement member.