Patent US4690822A successfully refreshed from Google Patents.
US4690822A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Novel drug carrier and pharmaceutical preparation comprising the same
Assignee: Astellas Pharma Inc
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Filing: 1986-03-12
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Granted: 1987-09-01
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Expires: 2006-03-12
Abstract
Abstract The invention relates to a pharmaceutical oral capsule preparation filled with a substantially anhydrous mixture which is in solid or semi-solid form comprising: (a) a drug or a drug treated by a conventional manner, each of which is in solid form, and (b) a drug carrier which is a semi-solid mixture comprising a selected aqueous polymer and a selected liquid oil, the ratio of aqueous polymer to liquid oil by weight being 2:1 to 1:40.
Inventors
- 👤 Toshinobu Uemura
- 👤 Toshiaki Okhuma
- 👤 Kiyohide Shinooka
- 👤 Hiroshi Ishikuro
- 👤 Yoshio Ueda
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 14:59
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/48; A61K9/50; A61K9/5073; A61K9/5078; A61K9/4841; A61K9/4858; A61K9/4866
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
144 words
A pharmaceutical oral capsule preparation filled with a substantially anhydrous mixture which is in solid or semi-solid form comprising: (a) a drug or a drug treated by a conventional manner, each of which is in solid form, and (b) a drug carrier which is a semi-solid mixture comprising an aqueous polymer selected from the group consisting of polyethylene oxide, polyvinyl alcohol, polyvinyl pyrrolidone, hydroxypropylmethylcellulose, methylceullose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, sodium carboxymethylcellulose, dextran, gelatin, pectin, sodium poly(acrylic acid), carboxypolymethylene, poly-L-lysin, pullulan, sodium alginate, chitosan, acacia, gum tragacanth, xanthan gum, guar gum and karaya gum, and liquid oil selected from the group consisting of arachis oil, cottonseed oil, sesame oil, medium chain monoglyceride, medium chain diglyceride, medium chain triglyceride, liquid paraffin, squalene, squalane, oleic acid, linoleic acid, ethylene glycol, propylene glycol and glycerin, the ratio of aqueous polymer to liquid oil by weight being 2:1 to 1:40.
Claim 2
Dependent Claim
144 words
A pharmaceutical oral capsule preparation filled with a substantially anhydrous mixture which is in solid or semi-solid form comprising: (a) a drug or a drug treated by a conventional manner, each of which is in solid form, and (b) a drug carrier which is a semi-solid mixture comprising an aqueous polymer selected from the group consisting of polyethylene oxide, polyvinyl alcohol, polyvinyl pyrrolidone, hydroxypropylmethylcellulose, methylceullose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, sodium carboxymethylcellulose, dextran, gelatin, pectin, sodium poly(acrylic acid), carboxypolymethylene, poly-L-lysin, pullulan, sodium alginate, chitosan, acacia, gum tragacanth, xanthan gum, guar gum and karaya gum, and liquid oil selected from the group consisting of arachis oil, cottonseed oil, sesame oil, medium chain monoglyceride, medium chain diglyceride, medium chain triglyceride, liquid paraffin, squalene, squalane, oleic acid, linoleic acid, ethylene glycol, propylene glycol and glycerin, the ratio of aqueous polymer to liquid oil by weight being 2:1 to 1:40.
Claim 3
Dependent Claim
17 words
The pharmaceutical oral capsule preparation of claim 1, wherein the aqueous polymer is polyethylene oxide or hydroxypropylmethylcellulose.
Claim 4
Dependent Claim
16 words
The pharmaceutical oral capsule preparation of claim 1, wherein the liquid oil is medium chain triglyceride.
Claim 5
Dependent Claim
25 words
The pharmaceutical oral capsule preparation of claim 1, wherein the aqueous polymer is polyethylene oxide or hydroxypropylmethylcellulose and the liquid oil is medium chain triglyceride.
Claim 6
Dependent Claim
22 words
The pharmaceutical oral capsule preparation of claim 1, wherein the drug treated by a conventional manner is an enteric particle containing drug.
Claim 7
Dependent Claim
25 words
A method of controlling the gastrointestional transit rate of a pharmaceutical preparation which comprises orally administering to a subject the pharmaceutical preparation of claim 1.
References Cited (Backward Citations)
US3126321A
Cited
US2149005A
Cited
US2805977A
Cited
US2875130A
Cited
US3108046A
Cited
US3147187A
Cited
US3374146A
Cited
US3549555A
Cited
US3539465A
Cited
US3857933A
Cited
US3851051A
Cited
US4235870A
Cited
US3984494A
Cited
DE2553026A1
Cited
US4137300A
Cited
US4343789A
Cited
US4404183A
Cited
US4438847A
Cited
US4421736A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-08-31 | 1991-03-02 | 1991-09-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-08-31 | 1995-03-02 | 1995-09-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-08-31 | 1999-03-02 | 1999-09-01 | $7700.00 | Window Closed / Lapsed |