Patent US4683133A successfully refreshed from Google Patents.
US4683133A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for treating periodontal disease
Assignee: Vipont Pharmaceutical Inc
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Filing: 1985-08-20
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Granted: 1987-07-28
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Expires: 2005-08-20
Abstract
Abstract A self-administerable method of treating periodontal disease by providing a dilute aqueous solution of a non-toxic benzo-c-phenanthridine salt, pumping the solution through an orifice to provide a pulsating jet stream that is capable of penetrating directly into the periodontal pockets associated with periodontal disease, and applying the jet stream to diseased gingival tissue and into the periodontal pockets.
Inventors
- 👤 G. Lee Southard
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 14:07
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/49; A61K8/19; A61K8/27; A61Q; A61Q11/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
120 words
A self-administerable method for the treatment and control of periodontal disease by supragingival irrigation comprising, pumping a dilute aqueous solution of a non-toxic benzo-c-phenanthridine alkaloid salt at concentrations from about 22.5 ug/ml to about 10 mg/ml through an orifice to provide a jet stream at a rate of 250 cc/minute to 600 cc/minute and a pulsation rate of 20 to 200 cycles per second penetrating directly into periodontal pockets associated with periodontal disease, and applying the jet stream of dilute benzo-c-phenanthridine alkaloid salt solution along the margins between the teeth and gums and into the periodontal pockets of an individual with periodontal disease so as to cleanse the diseased tissues and to provide a residue of said benzo-c-phenanthridine alkaloid salt.
Claim 2
Dependent Claim
120 words
A self-administerable method for the treatment and control of periodontal disease by supragingival irrigation comprising, pumping a dilute aqueous solution of a non-toxic benzo-c-phenanthridine alkaloid salt at concentrations from about 22.5 ug/ml to about 10 mg/ml through an orifice to provide a jet stream at a rate of 250 cc/minute to 600 cc/minute and a pulsation rate of 20 to 200 cycles per second penetrating directly into periodontal pockets associated with periodontal disease, and applying the jet stream of dilute benzo-c-phenanthridine alkaloid salt solution along the margins between the teeth and gums and into the periodontal pockets of an individual with periodontal disease so as to cleanse the diseased tissues and to provide a residue of said benzo-c-phenanthridine alkaloid salt.
Claim 3
Dependent Claim
31 words
The method of claim 1 wherein said benzo-c-phenanthridine alkaloid salt is selected from the group consisting of non-toxic salts of sanguinarine, chelerythrine, protopine, sanguirubine, sanguilutine, chelylutine, macarpine, hemochelidonene, and mixtures thereof.
Claim 4
Dependent Claim
11 words
The method of claim 2 wherein the salt is sanguinarine chloride.
Claim 5
Dependent Claim
17 words
The method of claim 1 wherein the salt is a mixture of sanguinarine chloride and chelerythrine chloride.
Claim 6
Dependent Claim
13 words
The method of claim 3 wherein the dilute aqueous solution includes zinc chloride.
Claim 7
Dependent Claim
15 words
The method of claim 1 wherein the jet stream of fluid is a pulsating stream.
Claim 8
Dependent Claim
18 words
The method of claim 1 wherein the jet stream flow is interrupted in an interval between pulse peaks.
References Cited (Backward Citations)
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US4406881A
Cited
US4376115A
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US4489750A
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-07-27 | 1991-01-26 | 1991-07-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-07-27 | 1995-01-26 | 1995-07-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-07-27 | 1999-01-26 | 1999-07-28 | $7700.00 | Window Closed / Lapsed |