US4681872A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Erythromycin A 11,12-carbonate and method of use
Assignee: Abbott Laboratories
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Filing: 1985-11-12
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Granted: 1987-07-21
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Expires: 2005-11-12
Abstract
Abstract An erythromycin A derivative with high antimicrobial activity and improved pharmacokinetics is disclosed. 4''-Deoxyerythromycin A 11,12-carbonate and derivatives show superior in vitro and in vivo antimicrobial activity compared to erythromycin A, and when administered to animals has a serum half-life much prolonged over that of erythromycin A.
Inventors
- 👤 Leslie A. Freiberg
- 👤 Howard E. Gracey
- 👤 Andre G. Pernet
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 02:05
CPC Classifications
C; C07; C07H; C07H17/00; C07H17/04; C07H17/08
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
25 words
A compound of the formula ##STR3## where R is hydroxyl, or acyl of 1 to 6 carbon atoms, and pharmaceutically acceptable salts and esters thereof.
Claim 2
Dependent Claim
25 words
A compound of the formula ##STR3## where R is hydroxyl, or acyl of 1 to 6 carbon atoms, and pharmaceutically acceptable salts and esters thereof.
Claim 3
Dependent Claim
10 words
A compound according to claim 1 wherein R is hydroxyl.
Claim 4
Dependent Claim
25 words
A pharmaceutical composition in unit dosage form, comprising a therapeutically effective amount of a compound according to claim 1 in combination with a pharmaceutical carrier.
Claim 5
Dependent Claim
36 words
A method of treating and preventing bacterial infections in humans and lower animals in need of such treatment, comprising administering to the human or lower animal a therapeutically effective amount of the composition of claim 3.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-07-20 | 1991-01-19 | 1991-07-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-07-20 | 1995-01-19 | 1995-07-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-07-20 | 1999-01-19 | 1999-07-21 | $7700.00 | Window Closed / Lapsed |