US4382085A
Expired / Lapsed
US
⏱️ 0.0 years remaining
4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents
Assignee: Pfizer Inc
•
Filing: 1982-03-01
•
Granted: 1983-05-03
•
Expires: 2002-03-01
Abstract
Abstract 4''-Epi erythromycin A and 9-dihydro-4''-epi erythromycin A and derivatives thereof as useful antibacterial agents.
Inventors
- 👤 Frank C. Sciavolino
- 👤 Mark A. Guadliana
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 23:43
CPC Classifications
C; C07; C07H; C07H17/00; C07H17/04; C07H17/08; A; A61; A61P; A61P31/00; A61P31/04
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
91 words
A compound selected from the group consisting of a macrolide antibiotic of the formula: ##STR4## and the pharmaceutically acceptable acid addition salts thereof, wherein R is selected from the group consisting of hydrogen, alkanoyl having from two to three carbon atoms and ethyl succinyl; R 1 and R 2 when considered separately are, respectively, hydroxy and hydrogen; R 1 and R 2 when considered together are an oxo group; R 3 and R 4 when considered separately are each hydrogen; and R 3 and R 4 when considered together are >C═O.
Claim 2
Dependent Claim
91 words
A compound selected from the group consisting of a macrolide antibiotic of the formula: ##STR4## and the pharmaceutically acceptable acid addition salts thereof, wherein R is selected from the group consisting of hydrogen, alkanoyl having from two to three carbon atoms and ethyl succinyl; R 1 and R 2 when considered separately are, respectively, hydroxy and hydrogen; R 1 and R 2 when considered together are an oxo group; R 3 and R 4 when considered separately are each hydrogen; and R 3 and R 4 when considered together are >C═O.
Claim 3
Dependent Claim
18 words
A compound of claim 1 wherein R 1 and R 2 when considered together are an oxo group.
Claim 4
Dependent Claim
18 words
The compound of claim 2 wherein R is hydrogen and R 3 and R 4 are each hydrogen.
Claim 5
Dependent Claim
18 words
The compound of claim 2 wherein R is acetyl and R 3 and R 4 are each hydrogen.
Claim 6
Dependent Claim
18 words
The compound of claim 2 wherein R is hydrogen and R 3 and R 4 together are >C═O.
Claim 7
Dependent Claim
18 words
The compound of claim 2 wherein R is acetyl and R 3 and R 4 together are >C═O.
Claim 8
Dependent Claim
23 words
A compound of claim 1 wherein R 1 is hydroxy, R 2 is hydrogen and R 3 and R 4 together are >C═C.
Claim 9
Dependent Claim
9 words
The compound of claim 7 wherein R is hydrogen.
Claim 10
Dependent Claim
9 words
The compound of claim 7 wherein R is acetyl.
Claim 11
Dependent Claim
23 words
A compound of claim 1 wherein R 1 is hydroxy, R 2 is hydrogen and R 3 and R 4 are each hydrogen.
Claim 12
Dependent Claim
9 words
The compound of claim 10 wherein R is hydrogen.
Claim 13
Dependent Claim
9 words
The compound of claim 10 wherein R is acetyl.
Claim 14
Dependent Claim
29 words
An antibacterial pharmaceutical composition comprising from about 0.5 to about 90 percent by weight of the total composition a compound as claimed in claim 1 and a pharmaceutical carrier.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1986-05-02 | 1986-11-01 | 1987-05-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1990-05-02 | 1990-11-01 | 1991-05-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1994-05-02 | 1994-11-01 | 1995-05-03 | $7700.00 | Window Closed / Lapsed |