Patent US4681759A successfully refreshed from Google Patents.
US4681759A
Expired / Lapsed
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Rioprostil-PVP complex
Assignee: Ortho Pharmaceutical Corp
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Filing: 1985-05-08
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Granted: 1987-07-21
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Expires: 2005-05-08
Abstract
Abstract A rioprostil/PVP complex is disclosed which is formed by lyophilization, evaporation or spray drying processes, and formed into improved solid dosage form for oral administration of cytoprotection and gastrointestinal lesions.
Inventors
- 👤 Linda S. Porubcan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 22:33
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/557; A61K47/00; A61K47/50; A61K47/51; A61K47/56; A61K47/58
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
23 words
A rioprostil: non-crosslinked polyvinylpyrrolidone complex of 1 mole fraction of rioprostil per 21/2 mole fraction of polyvinylpyrrolidone monomeric subunits in dry solid form.
Claim 2
Dependent Claim
23 words
A rioprostil: non-crosslinked polyvinylpyrrolidone complex of 1 mole fraction of rioprostil per 21/2 mole fraction of polyvinylpyrrolidone monomeric subunits in dry solid form.
Claim 3
Dependent Claim
8 words
The complex of claim 1 in powdered form.
Claim 4
Dependent Claim
36 words
A pharmaceutical composition for oral administration to mammals to induce cytoprotection or prevent gastrointestinal lesions or treat gastrointestinal lesions comprising, as the active ingredient, the rioprostil: polyvinylpyrrolidone complex of claim 2 and a pharmaceutically acceptable carrier.
Claim 5
Dependent Claim
12 words
The pharmaceutical composition of claim 3 in the form of a tablet.
Claim 6
Dependent Claim
12 words
The pharmaceutical composition of claim 3 in the form of a capsule.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-07-20 | 1991-01-19 | 1991-07-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-07-20 | 1995-01-19 | 1995-07-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-07-20 | 1999-01-19 | 1999-07-21 | $7700.00 | Window Closed / Lapsed |