Veterinary dispenser delivering beneficial agent by gas power generated in situ

Claim 1

A dispenser for delivering a beneficial agent formulation to an environment of use, the dispenser comprising: (a) wall means for surrounding and forming an internal compartment; (b) passageway means in the wall for connecting the internal compartment with the exterior of the dispenser; (c) formulation means in the internal compartment comprising a beneficial agent formulation for absorbing thermal energy from the environment of use for making the beneficial agent formulation a deliverable formulation; and, (d) gas-generating means in the compartment for generating a gas in the presence of a fluid that passes through the wall means causing the gas-generating means to react and generate a gas that exerts pressure against the deliverable thermal energy sensitive formulation, thereby urging the deliverable formulation through the passageway means from the dispenser to the environment of use over time.

Claim 30

A method of administering to a ruminant a biologically active substance, said method comprising: (a) admitting orally into the ruminant a dispenser, the dispenser comprising: (1) a wall that surrounds and defines an internal lumen, the wall comprising a material permeable to the passage of fluid and substantially impermeable to the passage of biologically active substance; (2) first means in the lumen for containing a biologically active substance, said means a heat responsive composition that absorbs heat from the ruminant and thereby forms a dispensable composition for administering the biologically active substance; (3) a passageway in the dispenser communicating with the lumen for administering the biologically active substance from the dispenser; (4) second means in the lumen for generating a gas in the presence of fluid imbibed into the lumen for producing gaseous pressure against the first means for urging is from the lumen; (5) third means in the lumen for maintaining the dispenser in the ruminant over time, said third means having a density greater than the density of a fluid present in the rumen of a ruminant; and (6) administering the biologically active substance by the means containing the biologically active substance absorbing heat and the means for generating gas producing a gas, whereby through the combined operations the beneficial substance is delivered.

Claim 31

A method of administering to a ruminant a biologically active substance, said method comprising: (a) admitting orally into the ruminant a dispenser, the dispenser comprising: (1) a wall that surrounds and defines an internal lumen, the wall comprising a material permeable to the passage of fluid and substantially impermeable to the passage of biologically active substance; (2) first means in the lumen for containing a biologically active substance, said means a heat responsive composition that absorbs heat from the ruminant and thereby forms a dispensable composition for administering the biologically active substance; (3) a passageway in the dispenser communicating with the lumen for administering the biologically active substance from the dispenser; (4) second means in the lumen for generating a gas in the presence of fluid imbibed into the lumen for producing gaseous pressure against the first means for urging is from the lumen; (5) third means in the lumen for maintaining the dispenser in the ruminant over time, said third means having a density greater than the density of a fluid present in the rumen of a ruminant; and (6) administering the biologically active substance by the means containing the biologically active substance absorbing heat and the means for generating gas producing a gas, whereby through the combined operations the beneficial substance is delivered.