US4670248A
Expired / Lapsed
US
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Olivine bolus
Assignee: International Minerals and Chemical Corp
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Filing: 1985-08-15
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Granted: 1987-06-02
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Expires: 2005-08-15
Abstract
Abstract The present invention relates to a bolus adapted to be orally administered to ruminants. The bolus contains a mixture of a magnesium silicate, a binder, and a rumen-soluble material. The bolus of the present invention provides for the controlled release of supplemental magnesium as a means of preventing and combatting the disease known as hypomaganesemia. Optionally, the bolus of the present invention can serve as a carrier for various biologically active substances.
Inventors
- 👤 Brian R. Schricker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 23:21
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0053; A61K9/0068; A23; A23K; A23K40/00; A23K40/30; A23K40/35; A23K50/00; A23K50/10
Claims Analysis
Total Claims: 21
Claim 1
Independent Claim
113 words
A controlled release bolus for administering supplemental magnesium to ruminants over an extended period, comprising: from about 50 to about 95 weight percent of a magnesium silicate selected from the group consisting of olivine serpentine, dunite and peridot, from about 1 to about 50 weight percent of a rumen-soluble material selected from the group consisting of urea ammonium lactate, ammonium chloride, ammonium sodium phosphate, ammonium ferric citrate, ammonium cupric chloride, ammonium phosphate, ammonium sulfate, polyammonium phosphate, buiret, starch, glucose, fructose, lactose, galactose, calcium lactate, calcium glucose, sodium lactate, magnesium lactate, magnesium glucose, cupric glucose, cupric lactate, zinc glucose, and zinc lactate; and from about 0.5 to about 10 weight percent of a binder.
Claim 2
Dependent Claim
113 words
A controlled release bolus for administering supplemental magnesium to ruminants over an extended period, comprising: from about 50 to about 95 weight percent of a magnesium silicate selected from the group consisting of olivine serpentine, dunite and peridot, from about 1 to about 50 weight percent of a rumen-soluble material selected from the group consisting of urea ammonium lactate, ammonium chloride, ammonium sodium phosphate, ammonium ferric citrate, ammonium cupric chloride, ammonium phosphate, ammonium sulfate, polyammonium phosphate, buiret, starch, glucose, fructose, lactose, galactose, calcium lactate, calcium glucose, sodium lactate, magnesium lactate, magnesium glucose, cupric glucose, cupric lactate, zinc glucose, and zinc lactate; and from about 0.5 to about 10 weight percent of a binder.
Claim 3
Dependent Claim
11 words
The bolus of claim 1, wherein said magnesium silicate is olivine.
Claim 4
Dependent Claim
9 words
The bolus of claim 1, additionally containing a lubricant.
Claim 5
Dependent Claim
10 words
The bolus of claim 1, additionally containing further biological substances.
Claim 6
Dependent Claim
34 words
The bolus of claim 1, wherein said binder is selected from the group consisting of sodium bentonite, ethyl cellulose, stearic acid, calcium stearate, adipic acid, fumaric acid, polyethylene glycol, deacetylated chitlon and cellulose acetate.
Claim 7
Dependent Claim
31 words
The bolus of claim 3, wherein said lubricant is selected from the group consisting of magnesium stearate, sodium stearate, powdered stearic acid, talc, paraffin, cocoa butter, graphite, lycopodium or combinations thereof.
Claim 8
Dependent Claim
44 words
The bolus of claim 4, wherein said biological active substance is selected from the group consisting of nutritional trace elements, anti-bloat agents, sedatives, tranquilizers, anti-convulsants, muscle relaxants, antipyretics, anti-inflammatories, analgesics, antimicrobials, steroids, diuretics, neoplastics, hypoglycemics, amino acids, vitamins, ezymes, bacterial cultures, antibiotics and anthelmentics.
Claim 9
Dependent Claim
11 words
The bolus of claim 6, wherein said rumen-soluble material is urea.
Claim 10
Dependent Claim
27 words
The bolus of claim 7, wherein said trace element is selected from the group consisting of cobalt, nickel, copper, molybdenum, chromium, iron, iodine, zinc, selenium and manganese.
Claim 11
Dependent Claim
24 words
The bolus of claim 7, wherein said anti-bloat agent is selected from the group consisting of methylsilicones, acetbutdylate and polyoxyethylene derivatives of ricinoleic acid.
Claim 12
Dependent Claim
20 words
The bolus of claim 7, wherein said antibiotic is selected from the group consisting of penicillin, chlorotetrocycline, tetra-cycline and oxytetra-cyline.
Claim 13
Dependent Claim
39 words
The bolus of claim 7, wherein said antibiotic is a polyether ionophore antibiotic that is selected from the group consisting of monensn, nigericin, salinomycin, narasin, grisorixan, lonomycin, laidomycin, mutalomycin, alborixin, lasalocid, lysocellin, ionomycin, aabomycin, disnerycin, duamycin or mixtures thereof.
Claim 14
Dependent Claim
71 words
A controlled release bolus for administering supplemental magnesium to ruminants over an extended period, comprising: from about 50 to about 95 weight percent of a magnesium silicate selected from the group consisting of olivine, serpentine, dunite, and peridot; from about 1 to about 50 weight percent of a rumen-soluble material selected from the group consisting of urea and starch; and from about 0.5 to about 10 weight percent of a binder.
Claim 15
Dependent Claim
71 words
A controlled release bolus for administering supplemental magnesium to ruminants over an extended period, comprising: from about 50 to about 95 weight percent of a magnesium silicate selected from the group consisting of olivine, serpentine, dunite, and peridot; from about 1 to about 50 weight percent of a rumen-soluble material selected from the group consisting of urea and starch; and from about 0.5 to about 10 weight percent of a binder.
Claim 16
Dependent Claim
34 words
The bolus of claim 13, wherein said binder is selected from the group consisting of sodium bentonite, ethyl cellulose, stearic acid, calcium stearate, adipic acid, fumaric acid, polyethylene glycol, deacetylated chitlon and cellulose acetate.
Claim 17
Dependent Claim
31 words
The bolus of claim 13, additionally containing a lubricant selected from the group consisting of magnesium stearate, sodium stearate, powdered stearic acid, talc, paraffin, cocoa butter, graphite, lycopodium or combinations thereof.
Claim 18
Dependent Claim
47 words
A controlled release bolus for administering supplemental magnesium to ruminants over an extended period, comprising: from about 50 to about 95 weight percent of olivine; from about 1 to about 50 weight percent of urea; and from about 0.5 to about 10 weight percent of a binder.
Claim 19
Dependent Claim
47 words
A controlled release bolus for administering supplemental magnesium to ruminants over an extended period, comprising: from about 50 to about 95 weight percent of olivine; from about 1 to about 50 weight percent of urea; and from about 0.5 to about 10 weight percent of a binder.
Claim 20
Dependent Claim
34 words
The bolus of claim 16, wherein said binder is selected from the group consisting of sodium bentonite, ethyl cellulose, stearic acid, calcium stearate, adipic acid, fumaric acid, polyethylene glycol, deacetylated chitlon and cellulose acetate.
Claim 21
Dependent Claim
31 words
The bolus of claim 16, additionally containing a lubricant selected from the group consisting of magnesium stearate, sodium stearate, powdered stearic acid, talc, paraffin, cocoa butter, graphite, lycopodium or combinations thereof.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-06-01 | 1990-12-01 | 1991-06-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-06-01 | 1994-12-01 | 1995-06-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-06-01 | 1998-12-01 | 1999-06-02 | $7700.00 | Window Closed / Lapsed |