Patent NL167252B successfully refreshed from Google Patents.
Patent US4668677A successfully refreshed from Google Patents.
US4668677A
Expired / Lapsed
US
⏱️ 0.0 years remaining
4-phenylphthalazine derivatives, their preparation and their use as pharmaceuticals
Assignee: Mitsubishi Chemical Corp
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Filing: 1985-04-11
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Granted: 1987-05-26
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Expires: 2005-04-11
Abstract
Abstract Certain new 1-alkylamino-4-phenylphthalazine derivatives, 1-neopentylamino-4-phenylphthalazine and 1-(1-ethylpropylamino)-4-phenylphthalazine, having prominent activity to ameliorate circulatory disorders and prepared from the corresponding phthalazinones.
Inventors
- 👤 Yasuhiro Morinaka
- 👤 Katsuhiko Iseki
- 👤 Toshiji Kanayama
- 👤 Toshiaki Watanabe
- 👤 Hiroyoshi Nishi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 20:41
CPC Classifications
C; C07; C07D; C07D237/00; C07D237/26; C07D237/30; C07D237/34; A; A61; A61P; A61P7/00; A61P7/02; A61P9/00
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
22 words
A 1-alkylamino-4-phenylphthalazine compound of the formula ##STR8## wherein R is a neopentyl group or a 1-ethylpropyl group, and pharmaceutically acceptable salts thereof.
Claim 2
Dependent Claim
22 words
A 1-alkylamino-4-phenylphthalazine compound of the formula ##STR8## wherein R is a neopentyl group or a 1-ethylpropyl group, and pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim
7 words
1-Neopentylamino-4-phenylphthalazine of the formula of claim 1.
Claim 4
Dependent Claim
7 words
1-(1-Ethylpropylamino)-4-phenylphthalazine of the formula of claim 1.
Claim 5
Dependent Claim
41 words
A pharmaceutical composition comprising an effective amount of active ingredient with activity to treat ischemic cardiac diseases, cerebrovasculatory diseases and peripheral circulatory disturbance in combination with a pharmaceutical carrier, wherein said active ingredient is a compound as claimed in claim 1.
Claim 6
Dependent Claim
14 words
The pharmaceutical composition as claimed in claim 4, wherein said active ingredient is 1-neopentylamino-4-phenylphthalazine.
Claim 7
Dependent Claim
14 words
The pharmaceutical composition as claimed in claim 4, wherein said active ingredient is 1-(1-ethylpropylamino)-4-phenylphthalazine.
Claim 8
Dependent Claim
40 words
A method for the treatment of ischemic cardiac diseases, cerebrovasculatory diseases and peripheral circulatory disturbance in humans which comprises administering to humans suffering from these dysfunctions an effective amount of a compound as claimed in claim 1 for said treatment.
References Cited (Backward Citations)
US3274185A
Cited
GB1303061A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-05-25 | 1990-11-24 | 1991-05-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-05-25 | 1994-11-24 | 1995-05-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-05-25 | 1998-11-24 | 1999-05-26 | $7700.00 | Window Closed / Lapsed |