Patent US4657902A successfully refreshed from Google Patents.
US4657902A
Expired / Lapsed
US
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Therapeutic use of tin mesoporphyrin
Assignee: Rockefeller University
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Filing: 1985-03-25
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Granted: 1987-04-14
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Expires: 2005-03-25
Abstract
Abstract Use of the novel compound tin mesoporphyrin and compositions containing it to inhibit heme metabolism in mammals, to control the rate of tryptophan metabolism in mammals, and to increase the rate at which heme is excreted by mammals.
Inventors
- 👤 Attallah Kappas
- 👤 George S. Drummond
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 19:09
CPC Classifications
C; C07; C07D; C07D487/00; C07D487/22; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/40; A61P; A61P3/00; A61P7/00; A61P7/06
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
13 words
A pharmaceutical composition for parenteral administration comprising tin mesoporphyrin and pharmaceutically acceptable carrier.
Claim 2
Dependent Claim
13 words
A pharmaceutical composition for parenteral administration comprising tin mesoporphyrin and pharmaceutically acceptable carrier.
Claim 3
Dependent Claim
24 words
A pharmaceutical composition in dosage unit form for parenteral administration comprising tin mesoporphyrin at a concentration of 1-250 μm/liter in a pharmaceutically acceptable carrier.
Claim 4
Dependent Claim
24 words
A pharmaceutical composition in dosage unit form for parenteral administration comprising tin mesoporphyrin at a concentration of 1-250 μm/liter in a pharmaceutically acceptable carrier.
Claim 5
Dependent Claim
40 words
A pharmaceutical composition useful for decreasing the rate of metabolism of heme in mammals in need of such decreased rate comprising a buffered isotonic aqueous saline solution containing an amount of tin mesoporphyrin which is effective to decrease said rate.
Claim 6
Dependent Claim
40 words
A pharmaceutical composition useful for decreasing the rate of metabolism of heme in mammals in need of such decreased rate comprising a buffered isotonic aqueous saline solution containing an amount of tin mesoporphyrin which is effective to decrease said rate.
Claim 7
Dependent Claim
40 words
A pharmaceutical composition useful for decreasing the rate of metabolism of heme in mammals in need of such decreased rate comprising a buffered isotonic aqueous glucose solution containing an amount of tin mesoporphyrin which is effective to decrease said rate.
Claim 8
Dependent Claim
40 words
A pharmaceutical composition useful for decreasing the rate of metabolism of heme in mammals in need of such decreased rate comprising a buffered isotonic aqueous glucose solution containing an amount of tin mesoporphyrin which is effective to decrease said rate.
Claim 9
Dependent Claim
13 words
A pharmaceutical composition of claims 1, 3 or 4 in dosage unit form.
Claim 10
Independent Claim
37 words
A method of decreasing the rate of metabolism of heme in a mammal in need of such decreased rate which comprises parenteral administration of an amount of the tin mesoporphyrin which is sufficient to effect such decrease.
Claim 11
Independent Claim
37 words
A method of decreasing the rate of metabolism of heme in a mammal in need of such decreased rate which comprises parenteral administration of an amount of the tin mesoporphyrin which is sufficient to effect such decrease.
Claim 12
Dependent Claim
12 words
A method as in claim 6 wherein the mammal is a human.
Claim 13
Dependent Claim
23 words
A method as in claim 6 wherein the tin mesoporphyrin is parenterally administered in the form of a buffered isotonic aqueous saline solution.
Claim 14
Dependent Claim
12 words
A method as in claim 8 wherein the mammal is a human.
Claim 15
Dependent Claim
23 words
A method as in claim 6 wherein the tin mesoporphyrin is parenterally administered in the form of a buffered isotonic aqueous glucose solution.
Claim 16
Dependent Claim
12 words
A method as in claim 10 wherein the mammal is a human.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-04-13 | 1990-10-13 | 1991-04-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-04-13 | 1994-10-13 | 1995-04-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-04-13 | 1998-10-13 | 1999-04-14 | $7700.00 | Window Closed / Lapsed |