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Integral element for biological reaction and process for the preparation thereof

Assignee: Fujifilm Holdings Corp
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Filing: 1984-03-19
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Granted: 1987-04-14
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Expires: 2004-03-19
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Abstract

Abstract An integral element for biological reaction comprising at least two layers consisting essentially of: a composite porous biological reaction layer comprising a fibrous material and a particulate material to which an active substance capable of participating in a biochemical reaction is fixed, and a porous layer of a fibrous material, in which: (1) the weight ratio between the particulate material and the fibrous material ranges from 1:20 to 1:0.3 on dry basis; and (2) the particulate material is contained in an amount ranging from 1 to 60 g/m 2 .

Inventors

  • 👤 Yukio Yasuda
  • 👤 Nobuhito Masuda

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 15:23
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/74; G01N33/78; G01N33/52; G01N33/525; G01N33/53; G01N33/543; G01N33/54366; G01N33/54386; G01N33/54387; G01N33/54391; Y; Y10; Y10S; Y10S435/00; Y10S435/805; Y10S436/00; Y10S436/807; Y10S436/81

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 140 words
In an integral element for quantitative analysis of biochemically active components in a liquid sample which comprises a porous reaction layer comprising a fibrous material and an active substance being active to said biochemically active components and a second porous layer superposed on the porous reaction layer, the improvement which comprises: said porous reaction layer containing a particulate material in an amount ranging from 1 to 60 g/m 2 , the weight ratio of the particulate material to fibrous material being from 1:20 to 1:0.3 on a dry basis, the active substance being fixed to the particulate material, the porous reaction layer and the second porous layer being superposed under the condition that the fibrous material of the reaction layer and the fibrous material of the second porous layer are tangled with each other on the interface between these layers.
Claim 2
Dependent Claim 140 words
In an integral element for quantitative analysis of biochemically active components in a liquid sample which comprises a porous reaction layer comprising a fibrous material and an active substance being active to said biochemically active components and a second porous layer superposed on the porous reaction layer, the improvement which comprises: said porous reaction layer containing a particulate material in an amount ranging from 1 to 60 g/m 2 , the weight ratio of the particulate material to fibrous material being from 1:20 to 1:0.3 on a dry basis, the active substance being fixed to the particulate material, the porous reaction layer and the second porous layer being superposed under the condition that the fibrous material of the reaction layer and the fibrous material of the second porous layer are tangled with each other on the interface between these layers.
Claim 3
Dependent Claim 28 words
The integral element of claim 1 wherein said particulate material is in the form of sticks having a ratio between thickness and length ranging from 1:1 to 1:20.
Claim 4
Dependent Claim 22 words
The integral element of claim 1 wherein said particulate material is selected from the group consisting of agar, agarose and beaded agarose.
Claim 5
Dependent Claim 37 words
The integral element of claim 1 wherein the fibrous materials of the porous reaction layer and the second layer have a thickness ranging from 0.1 to 5 μm and a length ranging from 100 to 4,000 μm.
Claim 6
Dependent Claim 22 words
The integral element of claim 1 wherein the fibrous materials of the porous reaction layer and the second layer are glass fibers.

References Cited (Backward Citations)

US3306811A Cited
US3431162A Cited
US3992158A Cited
US4472498A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-04-13 1990-10-13 1991-04-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-04-13 1994-10-13 1995-04-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-04-13 1998-10-13 1999-04-14 $7700.00 Window Closed / Lapsed

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