US4657542A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Medical instrument used for storage of blood
Assignee: TEMUMO TRADING AS TERUMO Corp KK
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Filing: 1985-01-25
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Granted: 1987-04-14
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Expires: 2005-01-25
Abstract
Abstract A medical instrument is disclosed which is a shaped article of a resin composition comprising 100 parts by weight of a vinyl chloride type resin, 10 to 80 parts by weight of a di-n-alkyl ester of phthalic acid whose alkyl groups each possess 8 to 14 carbon atoms and whose numbers of carbon atoms in said alkyl groups average 9 to 14, and 1 to 18 parts by weight of a stabilizer. The medical instrument exudes only an extremely small amount of plasticizer and excels in permeability to gas.
Inventors
- 👤 Yoshinori Ohachi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 02:27
CPC Classifications
A; A61; A61L; A61L33/00; A61L33/06; A61L33/064; A61L33/0005; A61L33/0052; A61L33/0058; C; C08; C08K; C08K5/00; C08K5/04; C08K5/10; C08K5/12
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
148 words
A medical instrument used for at least one of storage of blood and as a conduit for blood, said medical instrument having at least a part thereof which is in contact with blood when said medical instrument is in service, said part comprising a shaped resin composition, said composition comprising 100 parts by weight of a vinyl chloride type resin, from 10 to 80 parts by weight of a di-n-alkyl ester of phthalic acid of the formula ##STR2## wherein, m and n each is an integer of from 8 to 14 and (m+n)/2 has a value of from 9 to 14, from 1 to 15 parts by weight of an epoxy compound; and from 0.01 to 8 parts by weight of a metallic soap; the permeability coefficient of said shaped resin composition to carbon dioxide gas is not less than 2.5×10 3 ml·mm/m 2 ·day·atm (at 30° C.).
Claim 2
Dependent Claim
148 words
A medical instrument used for at least one of storage of blood and as a conduit for blood, said medical instrument having at least a part thereof which is in contact with blood when said medical instrument is in service, said part comprising a shaped resin composition, said composition comprising 100 parts by weight of a vinyl chloride type resin, from 10 to 80 parts by weight of a di-n-alkyl ester of phthalic acid of the formula ##STR2## wherein, m and n each is an integer of from 8 to 14 and (m+n)/2 has a value of from 9 to 14, from 1 to 15 parts by weight of an epoxy compound; and from 0.01 to 8 parts by weight of a metallic soap; the permeability coefficient of said shaped resin composition to carbon dioxide gas is not less than 2.5×10 3 ml·mm/m 2 ·day·atm (at 30° C.).
Claim 3
Dependent Claim
19 words
The medical instrument of claim 1, wherein m and n each is an integer of from 9 to 12.
Claim 4
Dependent Claim
16 words
The medical instrument of claim 1, wherein said di-n-alkyl ester of phthalic acid is di-n-decyl phthalate.
Claim 5
Dependent Claim
63 words
The medical instrument of claim 1, wherein said at least one part is flexible, and said resin composition comprises 100 parts by weight of said vinyl chloride type resin, 40 to 70 parts by weight of said di-n-alkyl ester of phthalic acid, 5 to 10 parts by weight of said epoxy compound, and 0.05 to 5 parts by weight of the metallic soap.
Claim 6
Dependent Claim
24 words
The medical instrument of claim 4, wherein said epoxy compound is an epoxidized vegetagle oil and said metallic soap is a Ca-Zn metallic soap.
Claim 7
Dependent Claim
13 words
The medical instrument of claim 1, wherein the instrument is a blood bag.
Claim 8
Dependent Claim
19 words
The medical instrument of claim 6, wherein m and n each is an integer of from 9 to 12.
Claim 9
Dependent Claim
25 words
The medical instrument of claim 7, wherein said vinyl chloride type resin is polyvinyl chloride having an average polymerization degree of from 700 to 3000.
Claim 10
Dependent Claim
27 words
The medical instrument of claim 8, wherein said average polymerization degree is from 1000 to 2400 and wherein said di-n-alkyl ester of phthalic acid is di-n-decyl phthalate.
Claim 11
Independent Claim
131 words
The method of preserving blood comprising storing blood in a blood bag, said blood bag having internal portions which contact the blood, said internal portions comprising a shaped resin composition, said composition comprising 100 parts by weight of a vinyl chloride type resin, from 10 to 80 parts by weight of a di-n-alkyl ester of phthalic acid of the formula ##STR3## wherein, m and n each is an integer of from 8 to 14 and (m+n)/2 has a value of from 9 to 14, from 1 to 15 parts by weight of an epoxy compound; and from 0.01 to 8 parts by weight of a metallic soap; the permeability coefficient of said shaped resin composition to carbon dioxide gas is not less than 2.5×10 3 ml·mm/m 2 ·day·atm (at 30° C.).
Claim 12
Independent Claim
131 words
The method of preserving blood comprising storing blood in a blood bag, said blood bag having internal portions which contact the blood, said internal portions comprising a shaped resin composition, said composition comprising 100 parts by weight of a vinyl chloride type resin, from 10 to 80 parts by weight of a di-n-alkyl ester of phthalic acid of the formula ##STR3## wherein, m and n each is an integer of from 8 to 14 and (m+n)/2 has a value of from 9 to 14, from 1 to 15 parts by weight of an epoxy compound; and from 0.01 to 8 parts by weight of a metallic soap; the permeability coefficient of said shaped resin composition to carbon dioxide gas is not less than 2.5×10 3 ml·mm/m 2 ·day·atm (at 30° C.).
Claim 13
Dependent Claim
18 words
The process of claim 10, wherein m and n each is an integer of from 9 to 12.
Claim 14
Dependent Claim
15 words
The process of claim 10, wherein said di-n-alkyl ester of phthalic acid is di-n-decyl phthalate.
Claim 15
Dependent Claim
62 words
The process of claim 10, wherein said at least one part is flexible, and said resin composition comprises 100 parts by weight of said vinyl chloride type resin, 40 to 70 parts by weight of said di-n-alkyl ester of phthalic acid, 5 to 10 parts by weight of said epoxy compound, and 0.05 to 5 parts by weight of the metallic soap.
Claim 16
Dependent Claim
23 words
The process of claim 13, wherein said epoxy compound is an epoxidized vegetagle oil and said metallic soap is a Ca-Zn metallic soap.
Claim 17
Dependent Claim
17 words
The process of claim 14, wherein m and n is an integer of from 9 to 12.
Claim 18
Dependent Claim
23 words
The process of claim 15, said vinyl chloride type resin is polyvinyl chloride having an average polymerization degree of from 700 to 3000.
Claim 19
Dependent Claim
26 words
The process of claim 16, wherein said average polymerization degree is from 1000 to 2400 and wherein said di-n-alkyl ester of phthalic acid is di-n-decyl phthalate.
References Cited (Backward Citations)
GB875999A
Cited
GB1301312A
Cited
GB1447853A
Cited
US3940802A
Cited
US4082711A
Cited
US4193898A
Cited
GB2017112A
Cited
US4451259A
Cited
US4300559A
Cited
EP0054221A1
Cited
EP0057470A2
Cited
US4478961A
Cited
US4495312A
Cited
EP0095526A2
Cited
FR2542320A1
Cited
JPS59164066A
Cited
GB2139231A
Cited
JPS59189858A
Cited
DE3318875A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-04-13 | 1990-10-13 | 1991-04-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-04-13 | 1994-10-13 | 1995-04-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-04-13 | 1998-10-13 | 1999-04-14 | $7700.00 | Window Closed / Lapsed |