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US4656186A Expired / Lapsed US ⏱️ 0.0 years remaining

Tetrapyrrole therapeutic agents

Assignee: PORPHYRIN PRODUCTS Inc A CORP OF UTAH
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Filing: 1985-04-30
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Granted: 1987-04-07
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Expires: 2005-04-30
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Abstract

Abstract This invention relates to new fluorescent mono, di- or polyamide of an aminomonocarboxylic acid and a tetrapyrrole containing at least three carboxy groups of the structure: ##STR1## wherein Z is the amino acid residue and x is the tetrapyrrole residue and "n" is an integer from 1 to 4 inclusive.

Inventors

  • 👤 Jerry C. Bommer
  • 👤 Bruce F. Burnham

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 09:53
CPC Classifications
C; C07; C07D; C07D487/00; C07D487/22; A; A61; A61P; A61P35/00; A61P43/00

Claims Analysis

Total Claims: 23
Claim 1
Independent Claim 63 words
A fluorescent mono, di or polyamide of an amino acid containing one carboxy group and a tetrapyrrole compound of the formula: ##STR5## said amide being formed between the amino group of the amino acid and at least one of the carboxy moieties attached to said tetrapyrrole, wherein; X=H, vinyl, ethyl, acetyl or formyl; Y=methyl or formyl; M=methyl; and E=ethyl and pharmaceutically-acceptable salts thereof.
Claim 2
Dependent Claim 63 words
A fluorescent mono, di or polyamide of an amino acid containing one carboxy group and a tetrapyrrole compound of the formula: ##STR5## said amide being formed between the amino group of the amino acid and at least one of the carboxy moieties attached to said tetrapyrrole, wherein; X=H, vinyl, ethyl, acetyl or formyl; Y=methyl or formyl; M=methyl; and E=ethyl and pharmaceutically-acceptable salts thereof.
Claim 3
Dependent Claim 15 words
The amide according to claim 1 wherein the amino acid is an alpha amino acid.
Claim 4
Dependent Claim 16 words
The amide according to claim 1 wherein the amino acid is a polar alpha amino acid.
Claim 5
Dependent Claim 8 words
A mono- or diamide according to claim 1.
Claim 6
Dependent Claim 17 words
A mono- or diamide according to claim 1 wherein the amino acid is a polar amino acid.
Claim 7
Dependent Claim 7 words
Mono- or di-L-serinyl chlorin e 6 .
Claim 8
Dependent Claim 7 words
Mono- or di-L-serinyl chlorin e 6 .
Claim 9
Dependent Claim 7 words
Mono- or di-L-cysteinyl chlorin e 6 .
Claim 10
Dependent Claim 7 words
Mono- or di-L-cysteinyl chlorin e 6 .
Claim 11
Dependent Claim 7 words
Mono- or di-L-serinyl bacteriochlorin e 6 .
Claim 12
Dependent Claim 7 words
Mono- or di-L-serinyl bacteriochlorin e 6 .
Claim 13
Dependent Claim 7 words
Mono- or di-L-cysteinyl bacteriochlorin e 6 .
Claim 14
Dependent Claim 7 words
Mono- or di-L-cysteinyl bacteriochlorin e 6 .
Claim 15
Dependent Claim 7 words
Mono- or di-L-serinyl rhodin g 7 .
Claim 16
Dependent Claim 7 words
Mono- or di-L-serinyl rhodin g 7 .
Claim 17
Dependent Claim 7 words
Mono- or di-L-cysteinyl rhodin g 7 .
Claim 18
Dependent Claim 7 words
Mono- or di-L-cysteinyl rhodin g 7 .
Claim 19
Dependent Claim 7 words
Mono- or di-L-cysteinyl mesochlorin e 6 .
Claim 20
Dependent Claim 7 words
Mono- or di-L-cysteinyl mesochlorin e 6 .
Claim 21
Dependent Claim 7 words
Mono- or di-L-serinyl mesochlorin e 6 .
Claim 22
Dependent Claim 7 words
Mono- or di-L-serinyl mesochlorin e 6 .
Claim 23
Dependent Claim 20 words
A pharmaceutical composition comprising an effective therapeutic amount of a compound according to claim 1 and a pharmaceutical carrier therefor.

References Cited (Backward Citations)

US4393071A Cited
WO1984001382A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1990-04-06 1990-10-06 1991-04-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1994-04-06 1994-10-06 1995-04-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1998-04-06 1998-10-06 1999-04-07 $7700.00 Window Closed / Lapsed

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