Derivatives of glycinamide, their preparation and their use

Abstract

Abstract A glycinamide derivative of the general formula I: <IMAGE> (I) wherein: R is a linear or ramified alkyl group C5-C18, a linear or ramified alkenyl group C5, C6, C7, C8, C9, C10, C11, C12, C13, C14, C15, C16, C17 or C18, a linear or ramified alkynyl group C4-C10, a linear or ramified acyl group C4-C18, a linear or ramified alkyl group C1-C10, substituted by a phenoxy group, by a hydroxy radical, by an acetoxy radical, by a carboxy radical, by a linear or ramified alkoxycarbonyl group C1-C4, by a carbonyl radical, by a carboxaldehyde group, by an acetal or cetal group, by one or more phenyl groups, by one or more phenyl groups substituted by a halogen atom such as fluorine, chlorine or bromine, R1 represents hydrogen, a linear or ramified alkyl group C1, C2, C3, C4, C5, C6, C7, C8, C9 or C10, a linear or ramified acyl group C1-C6, a benzoyl group, a linear or ramified alkoxycarbonyl group C1, C2, C3, C4, C5, C6, C7 or C8, a carboxamidomethyl group, R2 represents hydrogen, a linear or ramified alkyl C1, C2, C3, a phenyl group, R3 represents hydrogen, a linear or ramified alkyl group C1, C2, C3, C4, C5, C6, C7 or C8, a phenyl group, optionally substituted by a halogen atom, such as fluorine, chlorine or bromine, R4 represents hydrogen, a linear or ramified alkyl group C1, C2, C3, C4, C5, C6, C7 or C8 as well as salts of these derivatives with non toxic and pharmaceutically usable acids.

Inventors

• 👤 Romeo Roncucci
• 👤 Claude L. Gillet
• 👤 Alexis H. Cordi
• 👤 Mark A. Martens
• 👤 Joseph L. Roba
• 👤 Paul J. Niebes
• 👤 Georges E. Lambelin
• 👤 William R. Van Dorsser

Bibliographic Details