Patent US4639364A successfully refreshed from Google Patents.
US4639364A
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Methods and compositions for enhancing magnetic resonance imaging
Assignee: Mallinckrodt Inc
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Filing: 1984-11-14
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Granted: 1987-01-27
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Expires: 2004-11-14
Abstract
Abstract Water soluble, substantially nontoxic salts of compounds of the formula: CF.sub.3 R wherein R is --SO 3 H, --SO 2 NH 2 or --PO 3 H 2 , are useful for obtaining fluorine magnetic resonance images of body organs and tissues. Illustrative salts of such compounds include sodium trifluoromethane sulfonate, N-methylglucaminium trifluoromethanesulfonate and N-methylglucaminium trifluoromethanesulfonamide.
Inventors
- 👤 George B. Hoey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:19
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/06; Y; Y10; Y10S; Y10S436/00; Y10S436/806; Y10T; Y10T436/00; Y10T436/24
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
74 words
A method for obtaining fluorine magnetic resonance images of body organs and tissues which comprises administering to a mammal a composition comprising a water soluble, substantially nontoxic salt of a compound of the formula: CF.sub.3 R wherein R is --SO 3 H, --SO 2 NH 2 or --PO 3 H 2 , in a sufficient amount to provide fluorine magnetic resonance images of said body organs and tissues, and imaging said organs and tissues.
Claim 2
Independent Claim
74 words
A method for obtaining fluorine magnetic resonance images of body organs and tissues which comprises administering to a mammal a composition comprising a water soluble, substantially nontoxic salt of a compound of the formula: CF.sub.3 R wherein R is --SO 3 H, --SO 2 NH 2 or --PO 3 H 2 , in a sufficient amount to provide fluorine magnetic resonance images of said body organs and tissues, and imaging said organs and tissues.
Claim 3
Dependent Claim
20 words
A method as set forth in claim 1 wherein said salt is a sodium or N-methylglucamine salt of said compound.
Claim 4
Dependent Claim
14 words
A method as set forth in claim 1 wherein said compound is trifluoromethanesulfonic acid.
Claim 5
Dependent Claim
13 words
A method as set forth in claim 1 wherein said compound is trifluoromethanesulfonamide.
Claim 6
Dependent Claim
14 words
A method as set forth in claim 1 wherein said compound is trifluoromethanephosphonic acid.
Claim 7
Dependent Claim
14 words
A method as set forth in claim 1 wherein said composition is sodium trifluoromethanesulfonate.
Claim 8
Dependent Claim
14 words
A method as set forth in claim 1 wherein said composition is N-methylglucaminium trifluoromethanesulfonate.
Claim 9
Dependent Claim
14 words
A method as set forth in claim 1 wherein said composition is N-methylglucaminium trifluoromethanesulfonamide.
Claim 10
Dependent Claim
19 words
A method as set forth in claim 1 wherein magnetic resonance images of blood flow and perfusion are obtained.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-01-26 | 1990-07-28 | 1991-01-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-01-26 | 1994-07-28 | 1995-01-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-01-26 | 1998-07-28 | 1999-01-27 | $7700.00 | Window Closed / Lapsed |