Patent US4627836A successfully refreshed from Google Patents.
US4627836A
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Cardiovascular prosthetic devices and implants with porous systems
Assignee: Pacesetter Inc
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Filing: 1983-06-30
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Granted: 1986-12-09
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Expires: 2003-06-30
Abstract
Abstract Novel cardiovascular prosthetic devices or implants having many useful cardiovascular applications comprise a porous surface and a network of interconnected interstitial pores below the surface in fluid flow communication with the surface pores. Tissue forms a smooth thin adherent coating of self-determining thickness on the porous surface making it resistant to the formation of the blood clots normally associated with the presence of foreign bodies in the blood stream. The device has particular utility in heart valves, pacemaker electrodes, blood pumps, blood stream filters, an artificial pancreas, vascular access tubes, small and large bore vascular grafts, blood pump diaphragms and vascular and intracardiac patches.
Inventors
- 👤 David C. MacGregor
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:22
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/05; A61N1/056; A61N1/0565; A61F; A61F2/00; A61F2/0077; A61F2/02; A61F2/04; A61F2/06; A61L; A61L27/00; A61L27/14; A61L27/18; A61L27/28; A61L27/34; A61L27/50; A61L27/56; A61L33/00; A61L33/02; A61L33/022; Y; Y10; Y10T; Y10T428/00; Y10T428/12; Y10T428/12014; Y10T428/12028; Y10T428/12042
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
120 words
A blood stream controlled release device comprising a hollow chamber containing a source of material to be released to blood and a porous surface of said chamber adapted to interface with a blood stream to establish communication between the blood stream and the interior of the chamber to permit said material release into the blood through a network of interconnected pores, said porous surface being formed of rigid material inert to blood and selected from metals, polymeric materials, ceramics and carbon, said porous surface having a porosity of at least 8% by volume up to the limit of coherence of the surface, an interstitial pore size of about 1 to about 1000 microns and a thickness up to 1 cm.
Claim 2
Dependent Claim
120 words
A blood stream controlled release device comprising a hollow chamber containing a source of material to be released to blood and a porous surface of said chamber adapted to interface with a blood stream to establish communication between the blood stream and the interior of the chamber to permit said material release into the blood through a network of interconnected pores, said porous surface being formed of rigid material inert to blood and selected from metals, polymeric materials, ceramics and carbon, said porous surface having a porosity of at least 8% by volume up to the limit of coherence of the surface, an interstitial pore size of about 1 to about 1000 microns and a thickness up to 1 cm.
Claim 3
Dependent Claim
14 words
The device of claim 1 wherein said substance is a hormone or a drug.
Claim 4
Dependent Claim
26 words
The device of claim 1 wherein said porosity is about 10 to about 50% by volume and said thickness is about 25 to about 500 microns.
Claim 5
Independent Claim
96 words
A method for the control of the release of substances into the blood stream, which comprises positioning a cardiovascular implant in the blood stream, said implant having a porous surface interfacing the blood and a network of interconnected pores in a subsurface in fluid flow communication with the porous surface, providing a source of a substance to be released into the blood in fluid flow communication with said subsurface on the opposite side thereof from said blood-interfacing surface, and releasing said substance through said subsurface and tissue growth on said blood-interfacing surface into said blood stream.
Claim 6
Independent Claim
96 words
A method for the control of the release of substances into the blood stream, which comprises positioning a cardiovascular implant in the blood stream, said implant having a porous surface interfacing the blood and a network of interconnected pores in a subsurface in fluid flow communication with the porous surface, providing a source of a substance to be released into the blood in fluid flow communication with said subsurface on the opposite side thereof from said blood-interfacing surface, and releasing said substance through said subsurface and tissue growth on said blood-interfacing surface into said blood stream.
Claim 7
Dependent Claim
14 words
The method of claim 4 wherein said substance is a drug or a hormone.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-12-08 | 1990-06-09 | 1990-12-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-12-08 | 1994-06-09 | 1994-12-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-12-08 | 1998-06-09 | 1998-12-09 | $7700.00 | Window Closed / Lapsed |