Patent US3104086A successfully refreshed from Google Patents.
Patent US4623484A successfully refreshed from Google Patents.
US4623484A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for peptide synthesis
Assignee: Research Corp
•
Filing: 1985-12-05
•
Granted: 1986-11-18
•
Expires: 2005-12-05
Abstract
Abstract This invention relates to polymers of the formula ##STR1## wherein Z is polystyrene, or a copolymer comprising styrene and a comonomer or comonomers. Y is selected from the group comprising nitro, acyl, carboxyl, formyl, cyano, carbalkoxy, sulfone, carboxyamide, or halogen; and R is hydroxy, aryloxy, alkoxy, halogen, formyloxy, acyloxy, cyano, amino, substituted amino, carboxyamine, thiol, alkylthio, arylthio, aralkylthio or acylthio, useful in peptide synthesis.
Inventors
- 👤 Louis A. Carpino
- 👤 Beri Cohen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 15:30
CPC Classifications
C; C08; C08F; C08F8/00; C08F8/14
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
88 words
In a process for producing peptides by reacting a protected amino acid with an activated polymeric support or substrate, the improvement comprising employing as said polymeric support or substrate compounds of the formula ##STR8## wherein Z is polystyrene, or a copolymer comprising styrene and a divinyl benzene comonomer. Y is selected from the group comprising nitro, acyl, carboxyl, formyl, cyano, carbalkoxy, aryl sulfone, alkyl sulfone, carboxyamide, or halogen; and R is hydroxy, aryloxy, alkoxy, halogen, formyloxy, acyloxy, cyano, amino acylamino, alkylamino, carboxyamine, thiol, alkylthio, arylthio, aralkylthio or acylthio.
Claim 2
Dependent Claim
88 words
In a process for producing peptides by reacting a protected amino acid with an activated polymeric support or substrate, the improvement comprising employing as said polymeric support or substrate compounds of the formula ##STR8## wherein Z is polystyrene, or a copolymer comprising styrene and a divinyl benzene comonomer. Y is selected from the group comprising nitro, acyl, carboxyl, formyl, cyano, carbalkoxy, aryl sulfone, alkyl sulfone, carboxyamide, or halogen; and R is hydroxy, aryloxy, alkoxy, halogen, formyloxy, acyloxy, cyano, amino acylamino, alkylamino, carboxyamine, thiol, alkylthio, arylthio, aralkylthio or acylthio.
Claim 3
Dependent Claim
12 words
The process of claim 1 wherein Y is nitro, acyl or carboxy.
Claim 4
Dependent Claim
11 words
The process of claim 1 wherein the compound is 3-nitro-4-hydroxybenzosulfonated polystryene.
References Cited (Backward Citations)
US3457243A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-11-17 | 1990-05-19 | 1990-11-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-11-17 | 1994-05-19 | 1994-11-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-11-17 | 1998-05-19 | 1998-11-18 | $7700.00 | Window Closed / Lapsed |