US4608350A
Expired / Lapsed
US
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Precursor solutions for biologically active glass
Assignee: EIDP Inc
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Filing: 1983-10-27
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Granted: 1986-08-26
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Expires: 2003-10-27
Abstract
Abstract An aqueous solution of precursors for biologically active glass, support particles coated with the solution, support particles coated with the glass, spheroidal particles of biologically active glass, processes for making the solution, coating the support, and for making the coated support and the spheroidal glass particles. The materials that comprise the biologically active glass are useful in prosthetic devices and implants for the human body.
Inventors
- 👤 Edward G. Howard, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 14:08
CPC Classifications
C; C03; C03C; C03C3/00; C03C3/04; C03C3/076; C03C3/089; A; A61; A61L; A61L27/00; A61L27/02; A61L27/10; A61L27/12; C03C1/00; C03C3/078; C03C3/097; A61F; A61F2310/00; A61F2310/00005; A61F2310/00179; A61F2310/00293; Y; Y10; Y10T; Y10T428/00; Y10T428/29; Y10T428/2982; Y10T428/2991; Y10T428/2993
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
118 words
A stable, aqueous acid solution consisting essentially of precursors that correspond to the components of a biologically active glass, the precursors being convertible to the biologically active glass by heat, the precursor solution showing no substantial amount of precipitation in one hour, the biologically active glass consisting essentially of these components: SiO 2 , 40 to 62 weight percent; Na 2 O, 10 to 32 weight percent; CaO, 10 to 32 weight percent; CaF 2 , 0 to 18 weight percent; P 2 O 5 , 0.1 to 12 weight percent; and B 2 O 3 , 0 to 20 weight percent; provided that Na 2 O and CaO, taken together, are at least about 30 weight percent.
Claim 2
Dependent Claim
118 words
A stable, aqueous acid solution consisting essentially of precursors that correspond to the components of a biologically active glass, the precursors being convertible to the biologically active glass by heat, the precursor solution showing no substantial amount of precipitation in one hour, the biologically active glass consisting essentially of these components: SiO 2 , 40 to 62 weight percent; Na 2 O, 10 to 32 weight percent; CaO, 10 to 32 weight percent; CaF 2 , 0 to 18 weight percent; P 2 O 5 , 0.1 to 12 weight percent; and B 2 O 3 , 0 to 20 weight percent; provided that Na 2 O and CaO, taken together, are at least about 30 weight percent.
Claim 3
Dependent Claim
61 words
A solution according to claim 1, consisting essentially of precursors that correspond to the components of a biologically active glass consisting essentially of: SiO 2 , about 40 weight percent; Na 2 O, about 24.5 weight percent; CaO, about 24.5 weight percent; P 2 O 5 , about 6 weight percent; and B 2 O 3 , about 5 weight percent.
Claim 4
Dependent Claim
13 words
A solution according to claim 1, having a pH less than about 5.
Claim 5
Dependent Claim
13 words
A solution according to claim 3, having a pH less than about 4.6.
Claim 6
Dependent Claim
13 words
A solution according to claim 4, having a pH less than about 3.8.
Claim 7
Dependent Claim
12 words
A solution according to claim 5, wherein the acid is nitric acid.
Claim 8
Dependent Claim
12 words
A solution according to claim 5, wherein the acid is formic acid.
Claim 9
Dependent Claim
266 words
A solution according to claim 1 wherein the precursors are selected from the group for SiO 2 : Na 2 O(SiO 2 ) 3 .38, Na 2 SiO 3 , (NaO) 2 Si(CH 3 ) 2 , silicic acid and colloidal SiO 2 ; for Na 2 O: Na 2 O(SiO 2 ) 3 .38, Na 2 SiO 3 , (NaO) 2 Si(CH 3 ) 2 , Na 3 PO 4 , Na 2 HPO 4 , NaH 2 PO 4 , Na 2 H 2 P 2 O 7 , NaNO 3 , Na 3 PO 3 , Na 2 HPO 3 , NaH 2 PO 3 , Na 3 PO 4 .H 2 O, and Na borates; for CaO: Ca salts of C 1 to C 4 alkanoic acid and Ca(NO 3 ) 2 ; for P 2 O 5 : H 3 PO 4 , Na 3 PO 4 , (NH 4 ) 3 PO 4 , Na 2 HPO 4 , (NH 4 ) 2 HPO 4 , NaH 2 PO 4 , NH 4 H 2 PO 4 , Na 2 H 2 P 2 O 7 , (NH 4 ) 2 H 2 P 2 O 7 , Na 3 PO 3 , (NH 4 ) 3 PO 3 , Na 2 HPO 3 , (NH 4 ) 2 HPO 3 , NaH 2 PO 3 , NH 4 H 2 PO 3 , Na 3 PO 4 .12H 2 O and (NH 4 ) 3 PO 4 .12H 2 O; and for B 2 O 3 : Na borates.
Claim 10
Dependent Claim
72 words
A solution according to claim 8 wherein the precursors are selected from the group for SiO 2 and Na 2 O: Na 2 O(SiO 2 ) 3 .38, for CaO: Ca(O 2 CH 2 ) 2 , for P 2 O 5 and Na 2 O: Na 3 PO 4 .12H 2 O, and for B 2 O 3 and Na 2 O: Na 2 B 4 O 7 .10H 2 O.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-08-25 | 1990-02-24 | 1990-08-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-08-25 | 1994-02-24 | 1994-08-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-08-25 | 1998-02-24 | 1998-08-26 | $7700.00 | Window Closed / Lapsed |