Arylhydroxamates useful as antiallergy agents

Claim 1

A compound having the structure ##STR72## wherein R 1 is lower alkyl, aryl, lower alkenyl aralkyl, or ##STR73## wherein n is 2 to 4 and X is hydroxy, alkoxy, amino, C 1 -C 4 -alkylamino or C 1 -C 4 -dialkylamino; R 2 is hydrogen or lower alkyl; and R 3 is C 1 -C 20 alkyl, C 3 -C 20 alkenyl, aryl, aryl-alkyl, cycloalkyl, aryl-alkenyl, lower alkoxy, lower alkenyloxy, aryl-alkoxy, aryloxy or cycloalkyloxy, including pharmaceutically acceptable monobasic and dibasic salts whereof, and wherein the term alkyl by itself or as part of another group is unsubstituted or substituted with a substituent which is a halo, trifluoromethyl, alkoxy, aryl, alkyl-aryl, haloaryl, cycloalkyl, alkylcycloalkyl, hydroxy, alkylamino, alkanoylamino, arylcarbonylamino, nitro, cyano, thiol or an alkylthio substituent, the term aryl by itself or as part of another group is unsubstituted or substituted with 1 or 2 halogens, 1 or 2 lower alkyl groups, 1 or 2 lower alkoxy groups, an aryl group, 1 or 2 hydroxyls, 1 or 2 alkylamino groups, 1 or 2 alkanoylamino groups, 1 or 2 arylcarbonylamino groups, 1 or 2 amino groups, 1 or 2 nitro groups, 1 or 2 cyano groups, 1 or 2 thiol groups and/or 1 or 2 alkythio groups; and the term cycloalkyl by itself or as Part of another group is unsubstituted or substituted with 1 or 2 halogens 1 or 2 lower alkyl groups, 1 or 2 alkoxy groups, an aryl group, 1 or 2 hydroxyls, 1 or 2 alkylamino groups, 1 or 2 alkanoylamino, 1 or 2 arylcarbonylamino groups, 1 or 2 amino groups, 1 or 2 nitro groups, 1 or 2 cyano groups, 1 or 2 thiol groups and/or 1 or 2 alkylthio groups.