US4604347A
Expired / Lapsed
US
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Analytical element for dry analysis
Assignee: Fujifilm Holdings Corp
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Filing: 1984-02-06
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Granted: 1986-08-05
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Expires: 2004-02-06
Abstract
Abstract An analytical element containing at least one reagent for dry analysis of analyte in a liquid sample, which contains a nondiffusive acid and a nondiffusive base in different phases, being capable of adjusting the surrounding pH of the reaction area of at least one reagent under fluid contact therebetween, and said at least one reagent is contained in said nondiffusive acid-containing phase or nondiffusive base-containing phase.
Inventors
- 👤 Fuminori Arai
- 👤 Mitsutoshi Tanaka
- 👤 Harumi Katsuyama
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 18:09
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/52; G01N33/525; G01N31/00; G01N31/22; G01N31/221; Y; Y10; Y10S; Y10S435/00; Y10S435/805
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
74 words
An analytical element for dry analysis of analyte in a liquid sample which contains a liquid-impermeable, light-transmissive support, a non-diffusive acid-containing layer, and a non-diffusive base-containing layer, the latter two layers being arranged on the support such that both layers upon liquid contact adjust the surrounding pH of a predetermined reaction area and wherein at least one of the latter two layers contains a reagent which participates in the analytical reaction which takes place.
Claim 2
Dependent Claim
74 words
An analytical element for dry analysis of analyte in a liquid sample which contains a liquid-impermeable, light-transmissive support, a non-diffusive acid-containing layer, and a non-diffusive base-containing layer, the latter two layers being arranged on the support such that both layers upon liquid contact adjust the surrounding pH of a predetermined reaction area and wherein at least one of the latter two layers contains a reagent which participates in the analytical reaction which takes place.
Claim 3
Dependent Claim
25 words
The analytical element as claimed in claim 1 in which the non-diffusive acid-containing layer and the non-diffusive base-containing layer are arranged adjacently to each other.
Claim 4
Dependent Claim
44 words
The analytical element as claimed in claim 1 in which a liquid sample-spreading layer is provided in the outermost position from the support and the non-diffusive acid-containing layer and the non-diffusive base containing-layer are each sandwiched between the support and the liquid sample-spreading layer.
Claim 5
Dependent Claim
34 words
The analytical element as claimed in claim 1 which comprises a liquid sample-spreading layer, a non-diffusive acid-containing reaction layer which contains the reagent, a non-diffusive base-containing layer, and a support arranged in this order.
Claim 6
Dependent Claim
28 words
The analytical element as claimed in claim 1, 2, or 3, in which said nondiffusive acid and nondiffusive base are an acidic polymer and a basic polymer, respectively.
Claim 7
Dependent Claim
63 words
The analytical element as claimed in claim 1, 2, or 3, in which said acidic polymer is a homopolymer or copolymer of an unsaturated monomer selected from the group consisting of p-styrenesulfonic acid, acrylic acid, methacrylic acid, maleic acid, maleic anhydride, maleic monoamide, monoester of maleic acid, N-(sulfoalkyl)acrylamide and N-(sulfoalkyl)methacrylamide, or a copolymer of said unsaturated monomer with other unsaturated monomer or monomers.
Claim 8
Dependent Claim
54 words
The analytical element as claimed in claim 1, 2, or 3, in which said basic polymer is a homopolymer or copolymer of an unsaturated monomer selected from the group consisting of 2-vinylpyridine, 4-vinylpyridine, N-vinylimidazole, 1-vinyl-3-alkyl-2,3-dihydroimidazole, 2-vinyl-1-alkylimidazole, (dialkylamino)alkylacrylate, (dialkylamino)alkylmethacrylate, N-/(dialkylamino)alkyl/acrylamide and N-/(dialkylamino)alkyl/methacrylamide, or a copolymer of said unsaturated monomer with other unsaturated monomer or monomers.
Claim 9
Dependent Claim
29 words
The analytical element as claimed in claim 1, 2, or 3, in which said reagent contained in said nondiffusive acid-containing phase or nondiffusive base-containing phase is a color-forming reagent.
Claim 10
Dependent Claim
24 words
The analytical element as claimed in claim 8, in which the reagent is capable of reacting with an enzyme or a substrate of enzyme.
Claim 11
Dependent Claim
17 words
The analytical element as claimed in claim 8, in which said color-forming reagent is a diazonium salt.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1989-08-04 | 1990-02-03 | 1990-08-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1993-08-04 | 1994-02-03 | 1994-08-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1997-08-04 | 1998-02-03 | 1998-08-05 | $7700.00 | Window Closed / Lapsed |