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US4604198A Expired / Lapsed US ⏱️ 0.0 years remaining

Multicartridge chromatography cartridge housing

Assignee: AMF INCORPORATED A CORP OF NEW JERSEY
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Filing: 1984-05-18
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Granted: 1986-08-05
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Expires: 2004-05-18
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Abstract

Abstract A multicartridge chromatography cartridge housing for use in supporting several chromatography cartridges in a parallel array is disclosed. A number of elongated cylindrical cartridge holders extend between a lower support plate and an upper support plate. Each such cartridge holder receives a chromatography cartridge which is held within the holder by suitable end caps and tie rods. Several truss rods serve to space the support plates from each other and to support the housing assembly. Fluid flow manifolds are secured to the lower and upper support plates and serve to distribute the fluid to, and consolidate the fluid received from the cartridges within the individual holders. The multicartridge chromatography cartridge housing in accordance with the present invention handles high fluid flow volumes with a small pressure drop and with a minimum hold up volume.

Inventors

  • 👤 Nils Dailey
  • 👤 Vishva Rai
  • 👤 Kenneth Southall
  • 👤 Timothy J. Webster

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 22:17
CPC Classifications
B; B01; B01D; B01D15/00; B01D15/08; B01D15/10; B01D15/18; B01D15/1864; B01D15/1885; G; G01; G01N; G01N30/00; G01N30/02; G01N30/60; G01N30/6047; G01N30/6091

Claims Analysis

Total Claims: 21
Claim 1
Independent Claim 121 words
A multicartridge housing for cylindrical chromatographic cartridges, each cartridge effective for the chromatographic separation of a fluid passing radially therethrough, said housing comprising: support means; a plurality of cartridge holders secured to said support means, each of said cartridge holders being structured and sized to surround a cartridge therein and a volume surrounding the cartridge, said volume in fluid communication with said cartridge for radial distribution of the fluid through the cartridge; an inlet fluid manifold means for distributing the fluid being separated to each of said holders for passage of the fluid radially through the cartridges therein; and an outlet fluid manifold means for consolidating the fluid from the holders after passage of the fluid radially through the cartridges therein.
Claim 2
Dependent Claim 121 words
A multicartridge housing for cylindrical chromatographic cartridges, each cartridge effective for the chromatographic separation of a fluid passing radially therethrough, said housing comprising: support means; a plurality of cartridge holders secured to said support means, each of said cartridge holders being structured and sized to surround a cartridge therein and a volume surrounding the cartridge, said volume in fluid communication with said cartridge for radial distribution of the fluid through the cartridge; an inlet fluid manifold means for distributing the fluid being separated to each of said holders for passage of the fluid radially through the cartridges therein; and an outlet fluid manifold means for consolidating the fluid from the holders after passage of the fluid radially through the cartridges therein.
Claim 3
Dependent Claim 18 words
The multicartridge housing in accordance with claim 1 wherein said support means includes lower and upper support plates.
Claim 4
Dependent Claim 20 words
The multicartridge housing of claim 2 wherein said lower and upper plates include a plurality of cartridge holder receiving apertures.
Claim 5
Dependent Claim 29 words
The multicartridge housing of claim 3 wherein said cartridge holders are elongated cylinders extending between said lower and upper plates and being secured in said cartridge holder receiving apertures.
Claim 6
Dependent Claim 26 words
The multicartridge housing in accordance with claim 1 wherein each of said cartridge holders includes an elongated hollow cylinder closed at its ends with end caps.
Claim 7
Dependent Claim 39 words
The multicartridge housing of claim 5 wherein each of said end caps includes a cylindrical wall portion receivable within an end of said cylinder and a flange extending radially outwardly from said wall portion at a first end thereof.
Claim 8
Dependent Claim 24 words
The multicartridge housing in accordance with claim 6 wherein said cylindrical wall portion of each of said end caps includes an O-ring receiving groove.
Claim 9
Dependent Claim 24 words
The multicartridge housing of claim 6 wherein each of said end caps is held in said ends of said cartridge holders by tie rods.
Claim 10
Dependent Claim 19 words
The multicartridge housing of claim 8 wherein said tie rods pass through tie rod receiving bores in said flanges.
Claim 11
Dependent Claim 16 words
The multicartridge housing in accordance with claim 5 wherein said end caps include fluid flow nozzles.
Claim 12
Dependent Claim 17 words
The multicartridge housing of claim 10 wherein each of said end caps includes two fluid flow nozzles.
Claim 13
Dependent Claim 37 words
The multicartridge housing of claim 11 wherein a first of said fluid flow nozzles terminates in a hose adaptor and a second of said fluid flow nozzles on each of said end caps receives a closure cap.
Claim 14
Dependent Claim 35 words
The multicartridge housing in accordance with claim 2 wherein said lower and upper support plates are spaced from each other by truss rods which extend between, and pass through said lower and upper support plates.
Claim 15
Dependent Claim 33 words
The multicartridge housing in accordance with claim 13 wherein support legs are secured to ends of said truss rods and extend generally perpendicularly of, and outwardly from said lower and upper support plates.
Claim 16
Dependent Claim 22 words
The multicartridge housing of claim 1 wherein each of said manifolds includes a generally cupshaped body element and a cooperating closure plate.
Claim 17
Dependent Claim 47 words
The multicartridge housing of claim 15 wherein said closure plate includes a central plug which is disposed within said cup shaped body element and which cooperates therewith to define a fluid chamber when said cup-shaped body element and said closure plate are assembled to form said manifold.
Claim 18
Dependent Claim 21 words
The multicartridge housing of claim 16 wherein said cup-shaped element includes a planar web defining the base of said cup-shaped element.
Claim 19
Dependent Claim 39 words
The multicartridge housing of claim 17 wherein said planar web includes a central aperture and a plurality of radially spaced apertures, each of said apertures being in fluid communication with said fluid chamber and receiving a threaded hose adaptor.
Claim 20
Dependent Claim 35 words
The multicartridge housing of claim 18 wherein said central aperture is connected to a fluid inflow or outlet line and wherein each of said radially spaced apertures is connected to one of said cartridge holders.
Claim 21
Dependent Claim 24 words
The multicartridge housing in accordance with claim 1 wherein said inlet fluid manifold and said outlet fluid manifold are secured to said support means.

References Cited (Backward Citations)

US3926809A Cited
US3922223A Cited
US4079009A Cited
US4259186A Cited
US4424127A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1989-08-04 1990-02-03 1990-08-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1993-08-04 1994-02-03 1994-08-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1997-08-04 1998-02-03 1998-08-05 $7700.00 Window Closed / Lapsed

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